Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384339990> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4384339990 endingPage "109" @default.
- W4384339990 startingPage "101" @default.
- W4384339990 abstract "Mucopolysaccharidosis is a lysosomal storage disorder, caused due to deficiency of enzymes required for the breakdown of Mucopolysaccharides. These undegraded Mucopolysaccharides accumulate in various tissues and cause characteristic features like neurological deficit, impaired motor function, developmental delay, hearing loss, behavioral problems, corneal clouding, glaucoma, respiratory distress, coarse facial features, skeletal deformities, and organomegaly. Based on deficient enzymes they have divided into subtypes Mucopolysaccharidosis I (MPS I) Hunter syndrome (I H / I HS / I S), Mucopolysaccharidosis II(MPS II) Hunter syndrome (severe and mild form), Mucopolysaccharidosis III (MPS III) Sanfilippo syndrome, Mucopolysaccharidosis IV(MPS IV) Morquio syndrome, Mucopolysaccharidosis VI(MPS VI) Maroteaux Lamy syndrome, Mucopolysaccharidosis VI (MPS VII) Sly syndrome. Diagnosis is classically based on clinical examination and urine analysis. Enzyme assay can also aid in diagnosis. Chorionic villi sampling and amniocentesis are also becoming popular. The main objective of treatment is to improve the quality of life. Symptomatic management includes daily exercise, physiotherapy, tonsillectomy, shunting surgery, and corneal transplantation. There are various recent concepts utilized for the treatment of Mucopolysaccharidosis. This review article emphasizes such treatment aspects as Hematopoietic stem cell therapy, Enzyme replacement therapy, Gene therapy, Nano-enabled therapy, and Substrate reduction therapy." @default.
- W4384339990 created "2023-07-15" @default.
- W4384339990 creator A5018803735 @default.
- W4384339990 creator A5034529932 @default.
- W4384339990 creator A5065376099 @default.
- W4384339990 creator A5075932024 @default.
- W4384339990 date "2023-07-15" @default.
- W4384339990 modified "2023-10-18" @default.
- W4384339990 title "Mucopolysaccharidosis: An overview and new treatment modalities" @default.
- W4384339990 cites W1508308889 @default.
- W4384339990 cites W1516985315 @default.
- W4384339990 cites W1541729841 @default.
- W4384339990 cites W1980579070 @default.
- W4384339990 cites W1981497391 @default.
- W4384339990 cites W1985193566 @default.
- W4384339990 cites W2011668168 @default.
- W4384339990 cites W2012973972 @default.
- W4384339990 cites W2048686056 @default.
- W4384339990 cites W2048865940 @default.
- W4384339990 cites W2089570508 @default.
- W4384339990 cites W2094919922 @default.
- W4384339990 cites W2106843179 @default.
- W4384339990 cites W2117675141 @default.
- W4384339990 cites W2343880322 @default.
- W4384339990 cites W2402092843 @default.
- W4384339990 cites W2901767113 @default.
- W4384339990 cites W2912843979 @default.
- W4384339990 cites W2916274774 @default.
- W4384339990 cites W2964480830 @default.
- W4384339990 cites W2994175683 @default.
- W4384339990 cites W2996122052 @default.
- W4384339990 cites W3109649824 @default.
- W4384339990 cites W3197088548 @default.
- W4384339990 cites W4236682734 @default.
- W4384339990 cites W4313225885 @default.
- W4384339990 doi "https://doi.org/10.18231/j.ijcbr.2023.016" @default.
- W4384339990 hasPublicationYear "2023" @default.
- W4384339990 type Work @default.
- W4384339990 citedByCount "0" @default.
- W4384339990 crossrefType "journal-article" @default.
- W4384339990 hasAuthorship W4384339990A5018803735 @default.
- W4384339990 hasAuthorship W4384339990A5034529932 @default.
- W4384339990 hasAuthorship W4384339990A5065376099 @default.
- W4384339990 hasAuthorship W4384339990A5075932024 @default.
- W4384339990 hasBestOaLocation W43843399901 @default.
- W4384339990 hasConcept C126322002 @default.
- W4384339990 hasConcept C142724271 @default.
- W4384339990 hasConcept C187212893 @default.
- W4384339990 hasConcept C21850170 @default.
- W4384339990 hasConcept C2778551932 @default.
- W4384339990 hasConcept C2779134260 @default.
- W4384339990 hasConcept C2779416428 @default.
- W4384339990 hasConcept C2779969927 @default.
- W4384339990 hasConcept C2910727661 @default.
- W4384339990 hasConcept C71924100 @default.
- W4384339990 hasConceptScore W4384339990C126322002 @default.
- W4384339990 hasConceptScore W4384339990C142724271 @default.
- W4384339990 hasConceptScore W4384339990C187212893 @default.
- W4384339990 hasConceptScore W4384339990C21850170 @default.
- W4384339990 hasConceptScore W4384339990C2778551932 @default.
- W4384339990 hasConceptScore W4384339990C2779134260 @default.
- W4384339990 hasConceptScore W4384339990C2779416428 @default.
- W4384339990 hasConceptScore W4384339990C2779969927 @default.
- W4384339990 hasConceptScore W4384339990C2910727661 @default.
- W4384339990 hasConceptScore W4384339990C71924100 @default.
- W4384339990 hasIssue "2" @default.
- W4384339990 hasLocation W43843399901 @default.
- W4384339990 hasOpenAccess W4384339990 @default.
- W4384339990 hasPrimaryLocation W43843399901 @default.
- W4384339990 hasRelatedWork W1772430936 @default.
- W4384339990 hasRelatedWork W1774028754 @default.
- W4384339990 hasRelatedWork W1996799982 @default.
- W4384339990 hasRelatedWork W2001982317 @default.
- W4384339990 hasRelatedWork W2002593000 @default.
- W4384339990 hasRelatedWork W2085691459 @default.
- W4384339990 hasRelatedWork W2112422433 @default.
- W4384339990 hasRelatedWork W2327110361 @default.
- W4384339990 hasRelatedWork W4296252931 @default.
- W4384339990 hasRelatedWork W2225131080 @default.
- W4384339990 hasVolume "10" @default.
- W4384339990 isParatext "false" @default.
- W4384339990 isRetracted "false" @default.
- W4384339990 workType "article" @default.