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• W4384343732 abstract "BackgroundThis study aimed to assess the effects of COVID-19 nonpharmaceutical interventions (NPIs) on the human papillomavirus (HPV) epidemic among men who have sex with men (MSM) in Xinjiang, China.MethodsIn our cohort study, we enrolled and followed HIV negative MSM in Xinjiang, China, between 2016 and 2022. Anal swab samples were collected to test for HPV DNA. We used interrupted time series analysis to characterize the temporal trends in HPV prevalence, incidence, and clearance before (1 September 2016 to 16 July 2020) and during the implementation of COVID-19 NPIs in Xinjiang (17 July 2020 to 31 March 2022). We used binomial segmented regression models to estimate the impact of COVID-19 NPIs on the HPV prevalence, incidence, and clearance.ResultsWe recruited 1296 MSM who contributed to a total of 5374 HPV tests in our study.COVID-19 NPIs were associated with a 37.9% decrease in the prevalence (prevalence ratio [PR], 0.621; 95% CI, 0.465 to 0.830), 52.2% decrease in the incidence (risk ratio [RR], 0.478; 0.377 to 0.606), and 40.4% increase in the clearance (RR, 1.404; 1.212 to 1.627) of HPV of any genotype after the implementation of COVID-19 NPIs in Xinjiang.ConclusionsCOVID-19 NPIs may lead to lower transmission and higher clearance of HPV among MSM. Future studies are needed to clarify longer-term impact of COVID-19 on the transmission and natural history of HPV among MSM." @default.
• W4384343732 created "2023-07-15" @default.
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• W4384343732 date "2023-09-01" @default.
• W4384343732 modified "2023-09-27" @default.
• W4384343732 title "Changes in human papillomavirus prevalence, incidence, and clearance among men who have sex with men in Xinjiang, China after implementation of nonpharmaceutical interventions to control COVID-19: An interrupted time series analysis" @default.
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• W4384343732 doi "https://doi.org/10.1016/j.ijid.2023.07.003" @default.
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