Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384397960> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4384397960 abstract "Several rare anaplastic lymphoma kinase (ALK) fusions have been identified in patients with non-small cell lung cancer (NSCLC); however, their treatment is not currently uniform. alectinib has been commonly used to treat rare ALK fusions in patients with NSCLC. This is the first study to report the occurrence of a uridine diphosphate-glucose pyrophosphorylase 2 (UGP2)-ALK fusion in a patient with NSCLC. The patient, who was hospitalized because of shortness of breath lasting 20 days, showed hydrothorax of the left lung under a computerized tomography chest scan. Pathological histology revealed lung adenocarcinoma in the patient. The UGP2-ALK mutation was found by next-generation sequencing. Subsequently, the patient was administered alectinib, and thereafter, the tumor lesion was observed to gradually shrink over the follow-up period. Progression-free survival reached 10 months as of the follow-up date, with no adverse events detected. This case report provides valuable insights into the clinical management of NSCLC patients with UGP2-ALK fusions. Moreover, alectinib is confirmed to be an appropriate therapeutic agent for such patients." @default.
- W4384397960 created "2023-07-16" @default.
- W4384397960 creator A5019585911 @default.
- W4384397960 creator A5020385603 @default.
- W4384397960 creator A5085642649 @default.
- W4384397960 creator A5086792966 @default.
- W4384397960 date "2023-09-20" @default.
- W4384397960 modified "2023-09-27" @default.
- W4384397960 title "Non-small cell lung cancer patient with a rare UGP2-ALK fusion protein responded well to alectinib: a case report" @default.
- W4384397960 cites W2041753434 @default.
- W4384397960 cites W2236017705 @default.
- W4384397960 cites W2239287815 @default.
- W4384397960 cites W2586889471 @default.
- W4384397960 cites W2839057355 @default.
- W4384397960 cites W2988002600 @default.
- W4384397960 cites W2991400485 @default.
- W4384397960 cites W3109932998 @default.
- W4384397960 cites W3112504741 @default.
- W4384397960 cites W3169719877 @default.
- W4384397960 cites W3184494519 @default.
- W4384397960 cites W3186371259 @default.
- W4384397960 cites W4290802163 @default.
- W4384397960 cites W4292980546 @default.
- W4384397960 cites W4295560716 @default.
- W4384397960 cites W4313648382 @default.
- W4384397960 doi "https://doi.org/10.1097/cad.0000000000001531" @default.
- W4384397960 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37450292" @default.
- W4384397960 hasPublicationYear "2023" @default.
- W4384397960 type Work @default.
- W4384397960 citedByCount "0" @default.
- W4384397960 crossrefType "journal-article" @default.
- W4384397960 hasAuthorship W4384397960A5019585911 @default.
- W4384397960 hasAuthorship W4384397960A5020385603 @default.
- W4384397960 hasAuthorship W4384397960A5085642649 @default.
- W4384397960 hasAuthorship W4384397960A5086792966 @default.
- W4384397960 hasConcept C117643217 @default.
- W4384397960 hasConcept C121608353 @default.
- W4384397960 hasConcept C126322002 @default.
- W4384397960 hasConcept C143998085 @default.
- W4384397960 hasConcept C2776232967 @default.
- W4384397960 hasConcept C2776256026 @default.
- W4384397960 hasConcept C2779220645 @default.
- W4384397960 hasConcept C2779422266 @default.
- W4384397960 hasConcept C2781182431 @default.
- W4384397960 hasConcept C71924100 @default.
- W4384397960 hasConceptScore W4384397960C117643217 @default.
- W4384397960 hasConceptScore W4384397960C121608353 @default.
- W4384397960 hasConceptScore W4384397960C126322002 @default.
- W4384397960 hasConceptScore W4384397960C143998085 @default.
- W4384397960 hasConceptScore W4384397960C2776232967 @default.
- W4384397960 hasConceptScore W4384397960C2776256026 @default.
- W4384397960 hasConceptScore W4384397960C2779220645 @default.
- W4384397960 hasConceptScore W4384397960C2779422266 @default.
- W4384397960 hasConceptScore W4384397960C2781182431 @default.
- W4384397960 hasConceptScore W4384397960C71924100 @default.
- W4384397960 hasLocation W43843979601 @default.
- W4384397960 hasLocation W43843979602 @default.
- W4384397960 hasOpenAccess W4384397960 @default.
- W4384397960 hasPrimaryLocation W43843979601 @default.
- W4384397960 hasRelatedWork W2400744927 @default.
- W4384397960 hasRelatedWork W2516942920 @default.
- W4384397960 hasRelatedWork W2624310346 @default.
- W4384397960 hasRelatedWork W2941535758 @default.
- W4384397960 hasRelatedWork W3035529108 @default.
- W4384397960 hasRelatedWork W3197633853 @default.
- W4384397960 hasRelatedWork W3199005851 @default.
- W4384397960 hasRelatedWork W4224235778 @default.
- W4384397960 hasRelatedWork W4226257711 @default.
- W4384397960 hasRelatedWork W4308551119 @default.
- W4384397960 isParatext "false" @default.
- W4384397960 isRetracted "false" @default.
- W4384397960 workType "article" @default.