FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384407424> ?p ?o ?g. }

• W4384407424 abstract "Abstract Genome size variation, largely driven by repeat content, is poorly understood within and among populations, limiting our understanding of its significance for adaptation. Here we characterize intraspecific variation in genome size and repeat content across 186 individuals of Amaranthus tuberculatus , a ubiquitous native weed that shows flowering time adaptation to climate across its range and in response to agriculture. K-mer based genome size estimates vary by up to 20% across individuals, with transposable elements, unknown repeats, and rDNAs being the primary contributors to this variability. The additive effect of this variation has important phenotypic consequences—individuals with more repeats, and thus larger genomes, show slower flowering times and growth rates. Compared to newly-characterized gene copy number and polygenic nucleotide changes underlying variation in flowering time, we show that genome size remains a modest but significant contributor to the genetic basis of flowering time. Differences in flowering time across sexes and habitats are not mirrored by genome size variation, but rather polygenic variation and a gene copy number variant within the ATP synthesis pathway. Repeat content nonetheless shows non-neutral distributions across the genome, and across latitudinal and environmental gradients, reflecting numerous governing processes that in turn influence quantitative genetic variation for phenotypes key to plant adaptation. Author Summary The remarkable and seemingly inconsequential variation in genome size across species has long been an enigma in evolutionary biology. Calling this viewpoint into question, correlations between genome size variation and traits linked to fitness are increasingly uncovered. While this suggests that DNA content itself may be a source of adaptive genetic variation, repeat elements that propagate at the cost of the host are known to largely mediate this variation and may thus limit adaptive potential. Here we look to disentangle these multi-level dynamics, characterizing repeat dynamics across the genome and among individuals across diverse collections of a widespread agricultural weed, linking repeat content to genome size variation, and characterizing the relative importance of its phenotypic consequences. In Amaranthus tuberculatus , we find non-neutral repeat distributions across individuals across the range, and while this repeat variation underlies both variation in genome size and flowering time, we show that it makes a relatively minor contribution to variation in a fitness-related trait across the landscape relative to monogenic and polygenic features. Together, this work broadens our perspective on the complex selective dynamics that govern intraspecific variation in genome size and traits key to fitness in plants." @default.
• W4384407424 created "2023-07-16" @default.
• W4384407424 creator A5029215028 @default.
• W4384407424 creator A5032227468 @default.
• W4384407424 creator A5034837242 @default.
• W4384407424 creator A5052676181 @default.
• W4384407424 date "2023-07-15" @default.
• W4384407424 modified "2023-09-25" @default.
• W4384407424 title "Genome size and repeat content contribute to a complex architecture of flowering time in<i>Amaranthus tuberculatus</i>" @default.
• W4384407424 cites W1494075612 @default.
• W4384407424 cites W16257422 @default.
• W4384407424 cites W1972071155 @default.
• W4384407424 cites W1972815947 @default.
• W4384407424 cites W1976439018 @default.
• W4384407424 cites W1980168725 @default.
• W4384407424 cites W1980340421 @default.
• W4384407424 cites W1988714210 @default.
• W4384407424 cites W1997724443 @default.
• W4384407424 cites W2004778468 @default.
• W4384407424 cites W2005874634 @default.
• W4384407424 cites W2007576706 @default.
• W4384407424 cites W2032970677 @default.
• W4384407424 cites W2042086471 @default.
• W4384407424 cites W2044231545 @default.
• W4384407424 cites W2045051799 @default.
• W4384407424 cites W2045843097 @default.
• W4384407424 cites W2047763053 @default.
• W4384407424 cites W2054254276 @default.
• W4384407424 cites W2064359884 @default.
• W4384407424 cites W2069712815 @default.
• W4384407424 cites W2076124986 @default.
• W4384407424 cites W2089901889 @default.
• W4384407424 cites W2101184565 @default.
• W4384407424 cites W2102362153 @default.
• W4384407424 cites W2102619694 @default.
• W4384407424 cites W2103297704 @default.
• W4384407424 cites W2104844659 @default.
• W4384407424 cites W2106963975 @default.
• W4384407424 cites W2116360795 @default.
• W4384407424 cites W2119451273 @default.
• W4384407424 cites W2126653400 @default.
• W4384407424 cites W2138556224 @default.
• W4384407424 cites W2143201739 @default.
• W4384407424 cites W2148591934 @default.
• W4384407424 cites W2148967384 @default.
• W4384407424 cites W2152123303 @default.
• W4384407424 cites W2159129223 @default.
• W4384407424 cites W2166976364 @default.
• W4384407424 cites W2170157588 @default.
• W4384407424 cites W2253646948 @default.
• W4384407424 cites W2254186441 @default.
• W4384407424 cites W2268449056 @default.
• W4384407424 cites W2279483750 @default.
• W4384407424 cites W2394727514 @default.
• W4384407424 cites W2437865583 @default.
• W4384407424 cites W2529327441 @default.
• W4384407424 cites W2536321379 @default.
• W4384407424 cites W2560831462 @default.
• W4384407424 cites W2567849983 @default.
• W4384407424 cites W2583363792 @default.
• W4384407424 cites W2606666366 @default.
• W4384407424 cites W2611735579 @default.
• W4384407424 cites W2751405513 @default.
• W4384407424 cites W2767660457 @default.
• W4384407424 cites W2772231999 @default.
• W4384407424 cites W2785895330 @default.
• W4384407424 cites W2793814349 @default.
• W4384407424 cites W2794163654 @default.
• W4384407424 cites W2794395750 @default.
• W4384407424 cites W2884952480 @default.
• W4384407424 cites W2894625652 @default.
• W4384407424 cites W2903245274 @default.
• W4384407424 cites W2904216625 @default.
• W4384407424 cites W2913738804 @default.
• W4384407424 cites W2917498696 @default.
• W4384407424 cites W2923400604 @default.
• W4384407424 cites W2924359406 @default.
• W4384407424 cites W2949086682 @default.
• W4384407424 cites W2949616733 @default.
• W4384407424 cites W2950006249 @default.
• W4384407424 cites W2950097532 @default.
• W4384407424 cites W2952596949 @default.
• W4384407424 cites W2952719668 @default.
• W4384407424 cites W2956150032 @default.
• W4384407424 cites W2958787013 @default.
• W4384407424 cites W2964583472 @default.
• W4384407424 cites W2975214507 @default.
• W4384407424 cites W2977595467 @default.
• W4384407424 cites W2978623500 @default.
• W4384407424 cites W2994632914 @default.
• W4384407424 cites W3008105842 @default.
• W4384407424 cites W3012094285 @default.
• W4384407424 cites W3017049640 @default.
• W4384407424 cites W3040417581 @default.
• W4384407424 cites W3134486295 @default.
• W4384407424 cites W3134709103 @default.
• W4384407424 cites W3153877471 @default.
• W4384407424 cites W3160915485 @default.
• W4384407424 cites W3205442753 @default.
• W4384407424 cites W3211362509 @default.

• next