Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384407629> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W4384407629 endingPage "0194" @default.
- W4384407629 startingPage "jrheum.2023" @default.
- W4384407629 abstract "To explore residual disease, defined as substantial symptoms and disease burden despite a remission or low disease activity (LDA) state, in patients with axial spondyloarthritis (axSpA), and to determine which factors are associated with residual disease.For this cross-sectional observational study, 1 timepoint per patient was used from SpA-Net, a web-based monitoring registry for SpA. Patients with an Ankylosing Spondylitis Disease Activity Score (ASDAS) < 2.1 (LDA) were included. Indicators of residual disease (outcomes) included fatigue (primary outcome), pain, physical functioning, health-related quality of life (HRQOL), and peripheral symptoms. Sex was the primary explanatory factor for residual disease. Other explanatory factors included demographics and disease-related factors. Associations between these factors and presence and extent of residual disease were explored using logistic and linear regression.In total, 267 patients in an LDA state were included. Mean age was 50.6 (SD 14.3) years and 100 (37.5%) were female. Residual disease occurred frequently (n = 114 [42.7%] had fatigue scores > 4/10; n = 34 [17.8%] had pain scores > 4/10), including in those in remission (ASDAS < 1.3). Physical HRQOL was reduced in 27% and moderate/poor in 33%. Multivariable regression analyses showed that reported fatigue was more severe and prevalent in female patients (fatigue severity [0-10]: Bfemale = 0.78, 95% CI 0.18- 1.38; fatigue > 4/10: ORfemale = 3.29, 95% CI 1.74-6.20). Other indicators of residual disease (ie, pain, peripheral symptoms, physical HRQOL) were also more severe and/or more prevalent in females.Residual disease is frequent in patients with axSpA who are in an LDA state, including remission, and it is particularly prevalent in female patients. Future studies should address how to manage or prevent residual disease in axSpA." @default.
- W4384407629 created "2023-07-16" @default.
- W4384407629 creator A5028817810 @default.
- W4384407629 creator A5031008536 @default.
- W4384407629 creator A5062170314 @default.
- W4384407629 creator A5091151755 @default.
- W4384407629 date "2023-07-15" @default.
- W4384407629 modified "2023-09-25" @default.
- W4384407629 title "Factors associated with residual disease in axial spondyloarthritis: results from a clinical practice registry" @default.
- W4384407629 doi "https://doi.org/10.3899/jrheum.2023-0194" @default.
- W4384407629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37453735" @default.
- W4384407629 hasPublicationYear "2023" @default.
- W4384407629 type Work @default.
- W4384407629 citedByCount "0" @default.
- W4384407629 crossrefType "journal-article" @default.
- W4384407629 hasAuthorship W4384407629A5028817810 @default.
- W4384407629 hasAuthorship W4384407629A5031008536 @default.
- W4384407629 hasAuthorship W4384407629A5062170314 @default.
- W4384407629 hasAuthorship W4384407629A5091151755 @default.
- W4384407629 hasConcept C126322002 @default.
- W4384407629 hasConcept C142052008 @default.
- W4384407629 hasConcept C142724271 @default.
- W4384407629 hasConcept C151956035 @default.
- W4384407629 hasConcept C159110408 @default.
- W4384407629 hasConcept C1862650 @default.
- W4384407629 hasConcept C2777402515 @default.
- W4384407629 hasConcept C2779134260 @default.
- W4384407629 hasConcept C2779951463 @default.
- W4384407629 hasConcept C30036603 @default.
- W4384407629 hasConcept C71924100 @default.
- W4384407629 hasConceptScore W4384407629C126322002 @default.
- W4384407629 hasConceptScore W4384407629C142052008 @default.
- W4384407629 hasConceptScore W4384407629C142724271 @default.
- W4384407629 hasConceptScore W4384407629C151956035 @default.
- W4384407629 hasConceptScore W4384407629C159110408 @default.
- W4384407629 hasConceptScore W4384407629C1862650 @default.
- W4384407629 hasConceptScore W4384407629C2777402515 @default.
- W4384407629 hasConceptScore W4384407629C2779134260 @default.
- W4384407629 hasConceptScore W4384407629C2779951463 @default.
- W4384407629 hasConceptScore W4384407629C30036603 @default.
- W4384407629 hasConceptScore W4384407629C71924100 @default.
- W4384407629 hasLocation W43844076291 @default.
- W4384407629 hasLocation W43844076292 @default.
- W4384407629 hasOpenAccess W4384407629 @default.
- W4384407629 hasPrimaryLocation W43844076291 @default.
- W4384407629 hasRelatedWork W192322703 @default.
- W4384407629 hasRelatedWork W2042791083 @default.
- W4384407629 hasRelatedWork W2102900383 @default.
- W4384407629 hasRelatedWork W2109158678 @default.
- W4384407629 hasRelatedWork W2318568462 @default.
- W4384407629 hasRelatedWork W2389709268 @default.
- W4384407629 hasRelatedWork W2991673254 @default.
- W4384407629 hasRelatedWork W3090239339 @default.
- W4384407629 hasRelatedWork W4247812811 @default.
- W4384407629 hasRelatedWork W49165275 @default.
- W4384407629 isParatext "false" @default.
- W4384407629 isRetracted "false" @default.
- W4384407629 workType "article" @default.