Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384408317> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4384408317 endingPage "54" @default.
- W4384408317 startingPage "47" @default.
- W4384408317 abstract "Signet-ring cell sinus histiocytosis (SRCSH) represents a distinctly rare reactive phenomenon predominantly affecting axillary and pelvic lymph nodes (LNs) of individuals with breast or prostatic adenocarcinoma. Reports of SRCSH in the literature are sparse with only 12 previous examples, thus underscoring the rarity of this process. Here, we report 4 additional SRCSH cases affecting 2 women and 2 men (M:F = 1:1; age range: 50 to 71 years; mean age = 61 years). In the 2 men, pelvic LNs were excised during radical cystoprostatectomy for genito-urinary cancer, while in one woman SRCSH was incidentally discovered in axillary LNs during mastectomy for breast adenocarcinoma. The other female patient presented with a history of aortic valve replacement and enlarged supraclavicular LNs. Microscopically, all involved LNs exhibited marked distention with filling of the subcapsular and medullary sinuses by sheets of signet-ring histiocytes containing a singular large, cytoplasmic vacuole and a crescentric nucleus. Overt cytologic atypia, pleomorphism and mitoses were absent. Erythrophagocytosis and occasional fibrosis were appreciated. None of the LNs with SRCSH showed evidence of metastatic tumor. Immunohistochemically, signet-ring sinus histiocytes were invariably positive for CD68 and CD163 but negative for pancytokeratins. The histopathologic characteristics of SRCSH, albeit bland, in conjunction with the patient’s medical history, may be misinterpreted as metastatic adenocarcinoma with signet-ring cell configuration. Immunohistochemical confirmation of the histiocytic lineage of the lesional cells in SRCSH usually suffices for rendering an accurate diagnosis. The underlying pathogenetic mechanism and possible biologic significance of SRCSH remain currently unknown." @default.
- W4384408317 created "2023-07-16" @default.
- W4384408317 creator A5001542130 @default.
- W4384408317 creator A5002114331 @default.
- W4384408317 creator A5064782323 @default.
- W4384408317 date "2023-09-01" @default.
- W4384408317 modified "2023-10-14" @default.
- W4384408317 title "Signet-Ring Cell Sinus Histiocytosis: Report of the Clinicopathologic Characteristics of 4 Cases with Emphasis on the Differential Diagnosis of Signet-Ring Cell Lesions" @default.
- W4384408317 cites W136323212 @default.
- W4384408317 cites W1556707240 @default.
- W4384408317 cites W1972771794 @default.
- W4384408317 cites W1977117524 @default.
- W4384408317 cites W1986596264 @default.
- W4384408317 cites W1998061327 @default.
- W4384408317 cites W2009640148 @default.
- W4384408317 cites W2009749959 @default.
- W4384408317 cites W2017378599 @default.
- W4384408317 cites W2023651705 @default.
- W4384408317 cites W2076244664 @default.
- W4384408317 cites W2088977972 @default.
- W4384408317 cites W2148098037 @default.
- W4384408317 cites W2312500092 @default.
- W4384408317 cites W2326419385 @default.
- W4384408317 cites W2330251961 @default.
- W4384408317 cites W2556311932 @default.
- W4384408317 cites W2765391606 @default.
- W4384408317 cites W2922123536 @default.
- W4384408317 cites W2999131289 @default.
- W4384408317 cites W3033805501 @default.
- W4384408317 cites W4285139706 @default.
- W4384408317 cites W4313205272 @default.
- W4384408317 cites W4313214778 @default.
- W4384408317 cites W4362667734 @default.
- W4384408317 cites W91141168 @default.
- W4384408317 doi "https://doi.org/10.1016/j.humpath.2023.07.006" @default.
- W4384408317 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37459900" @default.
- W4384408317 hasPublicationYear "2023" @default.
- W4384408317 type Work @default.
- W4384408317 citedByCount "0" @default.
- W4384408317 crossrefType "journal-article" @default.
- W4384408317 hasAuthorship W4384408317A5001542130 @default.
- W4384408317 hasAuthorship W4384408317A5002114331 @default.
- W4384408317 hasAuthorship W4384408317A5064782323 @default.
- W4384408317 hasConcept C121608353 @default.
- W4384408317 hasConcept C126322002 @default.
- W4384408317 hasConcept C142160229 @default.
- W4384408317 hasConcept C142724271 @default.
- W4384408317 hasConcept C189528381 @default.
- W4384408317 hasConcept C204232928 @default.
- W4384408317 hasConcept C2780238495 @default.
- W4384408317 hasConcept C2781182431 @default.
- W4384408317 hasConcept C43100952 @default.
- W4384408317 hasConcept C71924100 @default.
- W4384408317 hasConceptScore W4384408317C121608353 @default.
- W4384408317 hasConceptScore W4384408317C126322002 @default.
- W4384408317 hasConceptScore W4384408317C142160229 @default.
- W4384408317 hasConceptScore W4384408317C142724271 @default.
- W4384408317 hasConceptScore W4384408317C189528381 @default.
- W4384408317 hasConceptScore W4384408317C204232928 @default.
- W4384408317 hasConceptScore W4384408317C2780238495 @default.
- W4384408317 hasConceptScore W4384408317C2781182431 @default.
- W4384408317 hasConceptScore W4384408317C43100952 @default.
- W4384408317 hasConceptScore W4384408317C71924100 @default.
- W4384408317 hasLocation W43844083171 @default.
- W4384408317 hasLocation W43844083172 @default.
- W4384408317 hasOpenAccess W4384408317 @default.
- W4384408317 hasPrimaryLocation W43844083171 @default.
- W4384408317 hasRelatedWork W1965793764 @default.
- W4384408317 hasRelatedWork W2018524013 @default.
- W4384408317 hasRelatedWork W2026115196 @default.
- W4384408317 hasRelatedWork W2148587476 @default.
- W4384408317 hasRelatedWork W2339326149 @default.
- W4384408317 hasRelatedWork W2395486081 @default.
- W4384408317 hasRelatedWork W2406881420 @default.
- W4384408317 hasRelatedWork W2621002121 @default.
- W4384408317 hasRelatedWork W2775440963 @default.
- W4384408317 hasRelatedWork W2887893030 @default.
- W4384408317 hasVolume "139" @default.
- W4384408317 isParatext "false" @default.
- W4384408317 isRetracted "false" @default.
- W4384408317 workType "article" @default.