FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384434088> ?p ?o ?g. }

• W4384434088 endingPage "30" @default.
• W4384434088 startingPage "1" @default.
• W4384434088 abstract "This chapter provides a comprehensive overview of malignant gliomasMalignant glioma, the most common primary brain tumorPrimary brain tumor in adults. These tumors are varied in their cellular origin, geneticGenetics profile, and morphologyMorphology under the microscopeMicroscope, but together they share some of the most dismal prognoses of all neoplasmsNeoplasm in the body. Although there is currently no cure for malignant gliomaMalignant glioma, persistent efforts to improve outcomes in patients with these tumors have led to modest increases in survivalSurvival, and researchers worldwide continue to strive toward a deeper understanding of the factors that influence gliomaGliomas development and response to treatment. In addition to well-established epidemiology, clinical manifestations, and common histopathologic and radiologic features of malignant gliomasMalignant glioma, this section considers recent advances in molecular biologyMolecular biology that have led to a more nuanced understanding of the geneticGenetics changes that characterize the different types of malignant gliomaMalignant glioma, as well as their implications for treatment. Beyond the traditional classification of malignant gliomasMalignant glioma based on histopathological features, this chapter incorporates the World Health Organization’sWorld Health Organization (WHO) 2016 criteria for the classification of brain tumorsBrain tumor, with special focus on disease-defining geneticGenetics alterations and newly established subcategories of malignant gliomaMalignant glioma that were previously unidentifiable based on microscopic examination alone. Traditional therapeutic modalities that form the cornerstone of treatment for malignant gliomaMalignant glioma, such as aggressive surgical resectionSurgical resection followed by adjuvantAdjuvant chemotherapyChemotherapy and radiation therapyRadiation therapy, and the studies that support their efficacy are reviewed in detail. This provides a foundation for additional discussion of novel therapeutic methods such as immunotherapyImmunotherapy and convection-enhanced deliveryConvection-enhanced delivery (CED), as well as new techniques for enhancing extent of resectionExtent of resection (EOR) such as fluorescence-guided surgeryFluorescence-guided surgery." @default.
• W4384434088 created "2023-07-16" @default.
• W4384434088 creator A5001955582 @default.
• W4384434088 creator A5039131664 @default.
• W4384434088 creator A5039450749 @default.
• W4384434088 creator A5055848888 @default.
• W4384434088 date "2023-01-01" @default.
• W4384434088 modified "2023-10-01" @default.
• W4384434088 title "Malignant Glioma" @default.
• W4384434088 cites W1494085100 @default.
• W4384434088 cites W1594747697 @default.
• W4384434088 cites W1751296883 @default.
• W4384434088 cites W1778129295 @default.
• W4384434088 cites W1812256879 @default.
• W4384434088 cites W1881534971 @default.
• W4384434088 cites W1887747927 @default.
• W4384434088 cites W1897243882 @default.
• W4384434088 cites W1921809757 @default.
• W4384434088 cites W1967180587 @default.
• W4384434088 cites W197014098 @default.
• W4384434088 cites W1972875444 @default.
• W4384434088 cites W1974791502 @default.
• W4384434088 cites W1985642611 @default.
• W4384434088 cites W1986092833 @default.
• W4384434088 cites W1988756388 @default.
• W4384434088 cites W1996908572 @default.
• W4384434088 cites W2001493754 @default.
• W4384434088 cites W2003422441 @default.
• W4384434088 cites W2020151184 @default.
• W4384434088 cites W2021670941 @default.
• W4384434088 cites W2025183726 @default.
• W4384434088 cites W2030964595 @default.
• W4384434088 cites W2031171312 @default.
• W4384434088 cites W2033369193 @default.
• W4384434088 cites W2036044314 @default.
• W4384434088 cites W2036560693 @default.
• W4384434088 cites W2040374436 @default.
• W4384434088 cites W2040827479 @default.
• W4384434088 cites W2041507551 @default.
• W4384434088 cites W2047296435 @default.
• W4384434088 cites W2051107088 @default.
• W4384434088 cites W2053349906 @default.
• W4384434088 cites W2053450987 @default.
• W4384434088 cites W2053535808 @default.
• W4384434088 cites W2060132600 @default.
• W4384434088 cites W2064214863 @default.
• W4384434088 cites W2072441383 @default.
• W4384434088 cites W2074242592 @default.
• W4384434088 cites W2076566420 @default.
• W4384434088 cites W2076699304 @default.
• W4384434088 cites W2081504365 @default.
• W4384434088 cites W2081935151 @default.
• W4384434088 cites W2086438568 @default.
• W4384434088 cites W2088925558 @default.
• W4384434088 cites W2093783077 @default.
• W4384434088 cites W2094433085 @default.
• W4384434088 cites W2096287682 @default.
• W4384434088 cites W2100567246 @default.
• W4384434088 cites W2100795816 @default.
• W4384434088 cites W2105100844 @default.
• W4384434088 cites W2105348749 @default.
• W4384434088 cites W2105528101 @default.
• W4384434088 cites W2106824860 @default.
• W4384434088 cites W2107007091 @default.
• W4384434088 cites W2107008278 @default.
• W4384434088 cites W2108076325 @default.
• W4384434088 cites W2109816625 @default.
• W4384434088 cites W2110685305 @default.
• W4384434088 cites W2112495947 @default.
• W4384434088 cites W2113012900 @default.
• W4384434088 cites W2120963683 @default.
• W4384434088 cites W2120964417 @default.
• W4384434088 cites W2121170253 @default.
• W4384434088 cites W2121725961 @default.
• W4384434088 cites W2123151929 @default.
• W4384434088 cites W2125372543 @default.
• W4384434088 cites W2126817554 @default.
• W4384434088 cites W2130511906 @default.
• W4384434088 cites W2131117209 @default.
• W4384434088 cites W2133131144 @default.
• W4384434088 cites W2133865472 @default.
• W4384434088 cites W2140375000 @default.
• W4384434088 cites W2142630775 @default.
• W4384434088 cites W2147013683 @default.
• W4384434088 cites W2147016542 @default.
• W4384434088 cites W2148216778 @default.
• W4384434088 cites W2150638747 @default.
• W4384434088 cites W2152806275 @default.
• W4384434088 cites W2153391936 @default.
• W4384434088 cites W2154313451 @default.
• W4384434088 cites W2154898479 @default.
• W4384434088 cites W2155197551 @default.
• W4384434088 cites W2157101750 @default.
• W4384434088 cites W2164111169 @default.
• W4384434088 cites W2164675211 @default.
• W4384434088 cites W2165626419 @default.
• W4384434088 cites W2165650436 @default.
• W4384434088 cites W2168784615 @default.

• next