FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384455719> ?p ?o ?g. }

• W4384455719 abstract "ABSTRACT Previously published animal studies have shown positive skeletal effects with local or systemic administration of beta blockers (BBs). However, population studies have shown mixed effects on bone mineral density (BMD) and fracture risk with BB use. The goal of this study was to evaluate whether exposure to BB is associated with fracture nonunion. Fee-for-service Medicare beneficiaries with an extremity fracture were identified by International Classification of Diseases (ICD)-10 and current procedural terminology (CPT) codes from 2016-2019. Charlson Comorbidity Index (CCI) was assigned using diagnoses prior to index fracture and nonunion identified by ICD-10 or CPT codes within one year from index fracture diagnosis. Patients were classified by BB exposure based on Part D (Pharmacy) claims between 90 days prior to and one year following index fracture. Chi square and Student’s T-tests were performed on categorical and continuous variables, respectively. Logistic regression was performed to evaluate the association between BB use and nonunion, controlling for age, sex, race, and comorbidity. Total number of fractures meeting inclusion criteria was 253,266 with 45% of patients having used a BB during the study period. The incidence of nonunion was 3.9% overall. BBs were associated with a 13% increase in non-union for all fracture types, after controlling for age, sex, fracture location, and CCI (OR 1.13 [CI 1.06-1.20], p<.001). Results of this study suggest a negative influence of BB on bone healing, contrary to results of previously published animal models and epidemiologic observations, and demonstrate that BB use during fracture care is associated with significant increase in incidence of nonunion." @default.
• W4384455719 created "2023-07-16" @default.
• W4384455719 creator A5014338841 @default.
• W4384455719 creator A5017342461 @default.
• W4384455719 creator A5025092734 @default.
• W4384455719 creator A5029708537 @default.
• W4384455719 creator A5033847257 @default.
• W4384455719 creator A5039969940 @default.
• W4384455719 creator A5058984776 @default.
• W4384455719 creator A5064411475 @default.
• W4384455719 creator A5068093215 @default.
• W4384455719 creator A5074514214 @default.
• W4384455719 date "2023-07-16" @default.
• W4384455719 modified "2023-10-14" @default.
• W4384455719 title "Beta-blocker exposure is associated with nonunion in a geriatric cohort of 253,266 extremity fractures" @default.
• W4384455719 cites W1561293749 @default.
• W4384455719 cites W1593442063 @default.
• W4384455719 cites W1769990193 @default.
• W4384455719 cites W1968506930 @default.
• W4384455719 cites W1973927468 @default.
• W4384455719 cites W1974764904 @default.
• W4384455719 cites W1979448723 @default.
• W4384455719 cites W1983601471 @default.
• W4384455719 cites W1997508587 @default.
• W4384455719 cites W2002924549 @default.
• W4384455719 cites W2005204978 @default.
• W4384455719 cites W2025346159 @default.
• W4384455719 cites W2029040272 @default.
• W4384455719 cites W2036183972 @default.
• W4384455719 cites W2037707152 @default.
• W4384455719 cites W2039041739 @default.
• W4384455719 cites W2039260429 @default.
• W4384455719 cites W2046396082 @default.
• W4384455719 cites W2070656089 @default.
• W4384455719 cites W2080756176 @default.
• W4384455719 cites W2129574927 @default.
• W4384455719 cites W2147510409 @default.
• W4384455719 cites W2149154265 @default.
• W4384455719 cites W2152337064 @default.
• W4384455719 cites W2154478484 @default.
• W4384455719 cites W2156972609 @default.
• W4384455719 cites W2159921044 @default.
• W4384455719 cites W2182850738 @default.
• W4384455719 cites W2761672379 @default.
• W4384455719 cites W2792575045 @default.
• W4384455719 cites W2803353103 @default.
• W4384455719 cites W2889322815 @default.
• W4384455719 cites W3203344782 @default.
• W4384455719 cites W4234159563 @default.
• W4384455719 cites W4280530929 @default.
• W4384455719 doi "https://doi.org/10.1101/2023.07.14.23292608" @default.
• W4384455719 hasPublicationYear "2023" @default.
• W4384455719 type Work @default.
• W4384455719 citedByCount "0" @default.
• W4384455719 crossrefType "posted-content" @default.
• W4384455719 hasAuthorship W4384455719A5014338841 @default.
• W4384455719 hasAuthorship W4384455719A5017342461 @default.
• W4384455719 hasAuthorship W4384455719A5025092734 @default.
• W4384455719 hasAuthorship W4384455719A5029708537 @default.
• W4384455719 hasAuthorship W4384455719A5033847257 @default.
• W4384455719 hasAuthorship W4384455719A5039969940 @default.
• W4384455719 hasAuthorship W4384455719A5058984776 @default.
• W4384455719 hasAuthorship W4384455719A5064411475 @default.
• W4384455719 hasAuthorship W4384455719A5068093215 @default.
• W4384455719 hasAuthorship W4384455719A5074514214 @default.
• W4384455719 hasBestOaLocation W43844557191 @default.
• W4384455719 hasConcept C126322002 @default.
• W4384455719 hasConcept C141071460 @default.
• W4384455719 hasConcept C151956035 @default.
• W4384455719 hasConcept C194828623 @default.
• W4384455719 hasConcept C2776541429 @default.
• W4384455719 hasConcept C2776886416 @default.
• W4384455719 hasConcept C2779159551 @default.
• W4384455719 hasConcept C2779330695 @default.
• W4384455719 hasConcept C2779513377 @default.
• W4384455719 hasConcept C2908647359 @default.
• W4384455719 hasConcept C3019063607 @default.
• W4384455719 hasConcept C45827449 @default.
• W4384455719 hasConcept C71924100 @default.
• W4384455719 hasConcept C72563966 @default.
• W4384455719 hasConcept C99454951 @default.
• W4384455719 hasConceptScore W4384455719C126322002 @default.
• W4384455719 hasConceptScore W4384455719C141071460 @default.
• W4384455719 hasConceptScore W4384455719C151956035 @default.
• W4384455719 hasConceptScore W4384455719C194828623 @default.
• W4384455719 hasConceptScore W4384455719C2776541429 @default.
• W4384455719 hasConceptScore W4384455719C2776886416 @default.
• W4384455719 hasConceptScore W4384455719C2779159551 @default.
• W4384455719 hasConceptScore W4384455719C2779330695 @default.
• W4384455719 hasConceptScore W4384455719C2779513377 @default.
• W4384455719 hasConceptScore W4384455719C2908647359 @default.
• W4384455719 hasConceptScore W4384455719C3019063607 @default.
• W4384455719 hasConceptScore W4384455719C45827449 @default.
• W4384455719 hasConceptScore W4384455719C71924100 @default.
• W4384455719 hasConceptScore W4384455719C72563966 @default.
• W4384455719 hasConceptScore W4384455719C99454951 @default.
• W4384455719 hasLocation W43844557191 @default.
• W4384455719 hasOpenAccess W4384455719 @default.
• W4384455719 hasPrimaryLocation W43844557191 @default.
• W4384455719 hasRelatedWork W1583557072 @default.

• next