FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384460900> ?p ?o ?g. }

• W4384460900 endingPage "113281" @default.
• W4384460900 startingPage "113281" @default.
• W4384460900 abstract "Soy allergy is a common health problem. Food structure may change the gastroduodenal digestion and absorption of soy proteins, thus leading to the modulation of the immunoreactivity of soy proteins. In this study, lactic acid bacterium (LAB)-fermented soy protein isolates (FSPIs) were prepared at four concentrations (0.2%–5.0%, w/v) to present various matrix structures (nongel, NG; weak gel, WG; medium gel, MG; and firm gel, FG) and subjected to in vitro dynamic gastroduodenal digestion model. The results of sandwich enzyme-linked immunosorbent and human serum IgE binding capacity assays demonstrated that FSPI gels, especially the FSPI-MG/WG digestates obtained at the early and medium stages of duodenal digestion (D-5 and D-30), possessed greater potency in immunoreactivity reduction than FSPI-NG and reduced to 1.9%–68.3%. The transepithelial transport study revealed that the immunoreactivity of FSPI-MG/WG D-5 and D-30 digestates decreased through the stimulation of interferon-γ production and the induction of dominant Th1/Th2 differentiation. Peptidomics and bioinformatics analyses illustrated that compared with FSPI-NG, the FSPI-gel structure promoted the epitope degradation of the major allergens glycinin G2/G5, β-conglycinin α/β subunit, P34, lectin, trypsin inhibitor, and basic 7S globulin. Spatial structure analysis showed that FSPI-gel elicited an overall promotion in the degradation of allergen epitopes located in interior and exterior regions and was dominated by α-helix and β-sheet secondary structures, whereas FSPI-MG/WG promoted the degradation of epitopes located in the interior region of glycinin/β-conglycinin and exterior region of P34/basic 7S globulin. This study suggested that the FSPI-gel structure is a promising food matrix for decreasing the allergenic potential of allergenic epitopes during gastroduodenal digestion and provided basic information on the production of hypoallergenic soy products." @default.
• W4384460900 created "2023-07-16" @default.
• W4384460900 creator A5000432967 @default.
• W4384460900 creator A5007806433 @default.
• W4384460900 creator A5058452492 @default.
• W4384460900 creator A5076184860 @default.
• W4384460900 creator A5078352289 @default.
• W4384460900 date "2023-11-01" @default.
• W4384460900 modified "2023-10-08" @default.
• W4384460900 title "Modulation of soy protein immunoreactivity by different matrix structures of lactic acid bacterium-induced soy protein gels: Epitope destruction during in vitro gastroduodenal digestion and absorption" @default.
• W4384460900 cites W1963687119 @default.
• W4384460900 cites W1972447401 @default.
• W4384460900 cites W1982210966 @default.
• W4384460900 cites W1986401583 @default.
• W4384460900 cites W2011536128 @default.
• W4384460900 cites W2020342012 @default.
• W4384460900 cites W2036148162 @default.
• W4384460900 cites W2038066303 @default.
• W4384460900 cites W2050806871 @default.
• W4384460900 cites W2052438475 @default.
• W4384460900 cites W2093753371 @default.
• W4384460900 cites W2095046205 @default.
• W4384460900 cites W2125012638 @default.
• W4384460900 cites W2127092918 @default.
• W4384460900 cites W2149462204 @default.
• W4384460900 cites W2226419578 @default.
• W4384460900 cites W2297127850 @default.
• W4384460900 cites W2471803248 @default.
• W4384460900 cites W2553538277 @default.
• W4384460900 cites W2738779347 @default.
• W4384460900 cites W2781615780 @default.
• W4384460900 cites W2793820307 @default.
• W4384460900 cites W2891101612 @default.
• W4384460900 cites W2914772022 @default.
• W4384460900 cites W2921382918 @default.
• W4384460900 cites W2946248261 @default.
• W4384460900 cites W2982144624 @default.
• W4384460900 cites W3010693122 @default.
• W4384460900 cites W3088916278 @default.
• W4384460900 cites W3112065995 @default.
• W4384460900 cites W3135941032 @default.
• W4384460900 cites W3158820625 @default.
• W4384460900 cites W3178799882 @default.
• W4384460900 cites W3201548405 @default.
• W4384460900 cites W3205471559 @default.
• W4384460900 cites W4200202791 @default.
• W4384460900 cites W4308294971 @default.
• W4384460900 cites W4309338367 @default.
• W4384460900 cites W4367435811 @default.
• W4384460900 doi "https://doi.org/10.1016/j.foodres.2023.113281" @default.
• W4384460900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37803593" @default.
• W4384460900 hasPublicationYear "2023" @default.
• W4384460900 type Work @default.
• W4384460900 citedByCount "0" @default.
• W4384460900 crossrefType "journal-article" @default.
• W4384460900 hasAuthorship W4384460900A5000432967 @default.
• W4384460900 hasAuthorship W4384460900A5007806433 @default.
• W4384460900 hasAuthorship W4384460900A5058452492 @default.
• W4384460900 hasAuthorship W4384460900A5076184860 @default.
• W4384460900 hasAuthorship W4384460900A5078352289 @default.
• W4384460900 hasConcept C116084860 @default.
• W4384460900 hasConcept C147483822 @default.
• W4384460900 hasConcept C153911025 @default.
• W4384460900 hasConcept C181199279 @default.
• W4384460900 hasConcept C185592680 @default.
• W4384460900 hasConcept C195616568 @default.
• W4384460900 hasConcept C203014093 @default.
• W4384460900 hasConcept C2777014122 @default.
• W4384460900 hasConcept C2777897731 @default.
• W4384460900 hasConcept C2780340462 @default.
• W4384460900 hasConcept C2781357212 @default.
• W4384460900 hasConcept C43617362 @default.
• W4384460900 hasConcept C55493867 @default.
• W4384460900 hasConcept C86803240 @default.
• W4384460900 hasConceptScore W4384460900C116084860 @default.
• W4384460900 hasConceptScore W4384460900C147483822 @default.
• W4384460900 hasConceptScore W4384460900C153911025 @default.
• W4384460900 hasConceptScore W4384460900C181199279 @default.
• W4384460900 hasConceptScore W4384460900C185592680 @default.
• W4384460900 hasConceptScore W4384460900C195616568 @default.
• W4384460900 hasConceptScore W4384460900C203014093 @default.
• W4384460900 hasConceptScore W4384460900C2777014122 @default.
• W4384460900 hasConceptScore W4384460900C2777897731 @default.
• W4384460900 hasConceptScore W4384460900C2780340462 @default.
• W4384460900 hasConceptScore W4384460900C2781357212 @default.
• W4384460900 hasConceptScore W4384460900C43617362 @default.
• W4384460900 hasConceptScore W4384460900C55493867 @default.
• W4384460900 hasConceptScore W4384460900C86803240 @default.
• W4384460900 hasFunder F4320321001 @default.
• W4384460900 hasFunder F4320322769 @default.
• W4384460900 hasFunder F4320327518 @default.
• W4384460900 hasLocation W43844609001 @default.
• W4384460900 hasLocation W43844609002 @default.
• W4384460900 hasOpenAccess W4384460900 @default.
• W4384460900 hasPrimaryLocation W43844609001 @default.
• W4384460900 hasRelatedWork W1586031216 @default.
• W4384460900 hasRelatedWork W1890721504 @default.
• W4384460900 hasRelatedWork W1971704222 @default.

• next