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• W4384498600 abstract "Exosomal programmed cell-death ligand 1 (ePD-L1) can influence immune inhibition and dysfunction. We were dedicated to unearthing the relation between ePD-L1 in blood and pathological characteristics as well as PD-L1 in tumor tissues. We recruited 65 non-small cell lung cancer (NSCLC) patients for exosome extraction and detected the blood ePD-L1 expression in these patients by enzyme-linked immunosorbent assay (ELISA) method. Besides, the correlation between blood ePD-L1 and patients' pathological characteristics was also analyzed. The expression of PD-L1 in tumor tissues was tested by immunohistochemistry (IHC) and its correlation with blood ePD-L1 expression level was analyzed by Spearman correlation coefficient. No significant correlation was observed in PD-L1 expression levels between blood-derived exosome and tumor tissue. Altogether, high blood ePD-L1 expression was relevant to NSCLC progression, while no such relevance to PD-L1 expression in tumor tissue." @default.
• W4384498600 created "2023-07-18" @default.
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• W4384498600 date "2023-07-17" @default.
• W4384498600 modified "2023-09-27" @default.
• W4384498600 title "A Study on the Clinical Significance of Blood Exosomal PD-L1 in Non-Small Cell Lung Cancer Patients and its Correlation with PD-L1 in Tumor Tissues" @default.
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• W4384498600 doi "https://doi.org/10.1055/a-2110-7497" @default.
• W4384498600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37459865" @default.
• W4384498600 hasPublicationYear "2023" @default.
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