FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384501952> ?p ?o ?g. }

• W4384501952 endingPage "152712" @default.
• W4384501952 startingPage "152712" @default.
• W4384501952 abstract "Previous studies have reported a correlation between the dysregulation of intestinal microbiota and the occurrence of asthma. This study aimed to investigate the effect of probiotic Lactobacillus rhamnosus 76 (LR76) on ovalbumin (OVA)-allergic mice and the mechanism of LR76 affecting mucus secretion in asthma. OVA-allergic mice were supplemented with LR76, and 16HBE cells induced by interleukin-13 (IL-13) were treated with LR76 supernatant (LR76-s) to observe the effect of LR76. In OVA-sensitized mice, LR76 alleviated the inflammatory cell infiltration in lung tissue and reduced the inflammatory cell counts of BALF. The expression level of mRNA, including Il4, Il5, Il13, Il25, Tgfb1, Il10, and Ifng, was decreased in the lung tissue of mice in the LR76 group compared with the OVA group. MUC5AC expression was down-regulated, while SCGB1A1 was up-regulated in the lung tissue of OVA-allergic mice after being supplemented with LR76 and in 16HBE cells induced by IL-13 after incubating with LR76-s. LR76 and LR76-s down-regulated the expression of proteins, including STAT6, p-STAT6, and SPDEF, and mRNA of STAT6 and SPDEF. In conclusion, LR76 alleviated airway inflammation and Th2 response in OVA-allergic mice and improved the mucus secretion of mouse lung tissue and 16HBE cells in the asthma model by down-regulating STAT6/SPDEF pathway." @default.
• W4384501952 created "2023-07-18" @default.
• W4384501952 creator A5019629988 @default.
• W4384501952 creator A5034831718 @default.
• W4384501952 creator A5035539440 @default.
• W4384501952 creator A5041989556 @default.
• W4384501952 creator A5053308705 @default.
• W4384501952 creator A5058380236 @default.
• W4384501952 creator A5063130264 @default.
• W4384501952 creator A5063512998 @default.
• W4384501952 creator A5067265947 @default.
• W4384501952 creator A5068793145 @default.
• W4384501952 creator A5080279954 @default.
• W4384501952 creator A5085660592 @default.
• W4384501952 creator A5088208982 @default.
• W4384501952 date "2023-09-01" @default.
• W4384501952 modified "2023-09-26" @default.
• W4384501952 title "Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway" @default.
• W4384501952 cites W1991284962 @default.
• W4384501952 cites W2002963540 @default.
• W4384501952 cites W2018872294 @default.
• W4384501952 cites W2048403514 @default.
• W4384501952 cites W2055750232 @default.
• W4384501952 cites W2073831602 @default.
• W4384501952 cites W2082538718 @default.
• W4384501952 cites W2124804278 @default.
• W4384501952 cites W2126765063 @default.
• W4384501952 cites W2178505996 @default.
• W4384501952 cites W2180159198 @default.
• W4384501952 cites W2483681232 @default.
• W4384501952 cites W2521983704 @default.
• W4384501952 cites W2528396364 @default.
• W4384501952 cites W2552046709 @default.
• W4384501952 cites W2582750136 @default.
• W4384501952 cites W2787852705 @default.
• W4384501952 cites W2795074754 @default.
• W4384501952 cites W2801344019 @default.
• W4384501952 cites W2801750686 @default.
• W4384501952 cites W2808057898 @default.
• W4384501952 cites W2884732880 @default.
• W4384501952 cites W2885662829 @default.
• W4384501952 cites W2888526997 @default.
• W4384501952 cites W2914828259 @default.
• W4384501952 cites W2933648730 @default.
• W4384501952 cites W2939247829 @default.
• W4384501952 cites W2972665961 @default.
• W4384501952 cites W3033438356 @default.
• W4384501952 cites W3033549805 @default.
• W4384501952 cites W3033599528 @default.
• W4384501952 cites W3041832488 @default.
• W4384501952 cites W3135216770 @default.
• W4384501952 cites W3188655966 @default.
• W4384501952 cites W3189119826 @default.
• W4384501952 cites W4280514570 @default.
• W4384501952 doi "https://doi.org/10.1016/j.imbio.2023.152712" @default.
• W4384501952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37515878" @default.
• W4384501952 hasPublicationYear "2023" @default.
• W4384501952 type Work @default.
• W4384501952 citedByCount "0" @default.
• W4384501952 crossrefType "journal-article" @default.
• W4384501952 hasAuthorship W4384501952A5019629988 @default.
• W4384501952 hasAuthorship W4384501952A5034831718 @default.
• W4384501952 hasAuthorship W4384501952A5035539440 @default.
• W4384501952 hasAuthorship W4384501952A5041989556 @default.
• W4384501952 hasAuthorship W4384501952A5053308705 @default.
• W4384501952 hasAuthorship W4384501952A5058380236 @default.
• W4384501952 hasAuthorship W4384501952A5063130264 @default.
• W4384501952 hasAuthorship W4384501952A5063512998 @default.
• W4384501952 hasAuthorship W4384501952A5067265947 @default.
• W4384501952 hasAuthorship W4384501952A5068793145 @default.
• W4384501952 hasAuthorship W4384501952A5080279954 @default.
• W4384501952 hasAuthorship W4384501952A5085660592 @default.
• W4384501952 hasAuthorship W4384501952A5088208982 @default.
• W4384501952 hasConcept C134018914 @default.
• W4384501952 hasConcept C141105273 @default.
• W4384501952 hasConcept C142724271 @default.
• W4384501952 hasConcept C145430368 @default.
• W4384501952 hasConcept C159654299 @default.
• W4384501952 hasConcept C18903297 @default.
• W4384501952 hasConcept C191732599 @default.
• W4384501952 hasConcept C203014093 @default.
• W4384501952 hasConcept C2775941134 @default.
• W4384501952 hasConcept C2776651480 @default.
• W4384501952 hasConcept C2776914184 @default.
• W4384501952 hasConcept C2776946954 @default.
• W4384501952 hasConcept C2776953665 @default.
• W4384501952 hasConcept C2777312293 @default.
• W4384501952 hasConcept C2779675166 @default.
• W4384501952 hasConcept C2780255968 @default.
• W4384501952 hasConcept C32046619 @default.
• W4384501952 hasConcept C49039625 @default.
• W4384501952 hasConcept C523546767 @default.
• W4384501952 hasConcept C529295009 @default.
• W4384501952 hasConcept C54355233 @default.
• W4384501952 hasConcept C71924100 @default.
• W4384501952 hasConcept C86803240 @default.
• W4384501952 hasConcept C8891405 @default.
• W4384501952 hasConceptScore W4384501952C134018914 @default.

• next