Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384558260> ?p ?o ?g. }
- W4384558260 endingPage "3641" @default.
- W4384558260 startingPage "3641" @default.
- W4384558260 abstract "In order to develop a biomarker predicting the efficacy of treatments for patients with esophageal squamous cell carcinoma (ESCC), we evaluated the subpopulation of T cells in ESCC patients treated with chemotherapy (CT), chemoradiotherapy (CRT), and nivolumab therapy (NT). Fifty-five ESCC patients were enrolled in this study, and peripheral blood samples were collected before and after CT or CRT and during NT. Frequencies of memory, differentiated, and exhausted T cells were evaluated using flow cytometry among cStages, treatment strategies, pathological responses of CT/CRT, and during NT. The frequencies of PD-1+ or TIM-3+CD4+ T cells were significantly higher in patients with cStage IV. PD-1+CD4+ and TIM-3+CD8+ T-cell populations were significantly higher in patients treated with CRT but were not associated with treatment response. The frequencies of both CD4+ and CD8+ CD45RA-CD27+CD127+ central memory T cells (TCM) were significantly decreased during the course of NT in the progressive disease group. Taken together, the alteration in frequency of CD45RA-CD27+CD127+ TCM during NT may be a biomarker to predict its therapeutic response in ESCC patients." @default.
- W4384558260 created "2023-07-18" @default.
- W4384558260 creator A5002878731 @default.
- W4384558260 creator A5009952197 @default.
- W4384558260 creator A5020726867 @default.
- W4384558260 creator A5025323978 @default.
- W4384558260 creator A5026506134 @default.
- W4384558260 creator A5035379638 @default.
- W4384558260 creator A5036056369 @default.
- W4384558260 creator A5078775589 @default.
- W4384558260 creator A5085503842 @default.
- W4384558260 creator A5086357025 @default.
- W4384558260 creator A5087712560 @default.
- W4384558260 creator A5089787707 @default.
- W4384558260 creator A5090779125 @default.
- W4384558260 creator A5090876871 @default.
- W4384558260 date "2023-07-16" @default.
- W4384558260 modified "2023-09-26" @default.
- W4384558260 title "A Potential Biomarker of Dynamic Change in Peripheral CD45RA−CD27+CD127+ Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma" @default.
- W4384558260 cites W1910012553 @default.
- W4384558260 cites W1965827638 @default.
- W4384558260 cites W1989273697 @default.
- W4384558260 cites W2067632426 @default.
- W4384558260 cites W2071014402 @default.
- W4384558260 cites W2098749176 @default.
- W4384558260 cites W2116435502 @default.
- W4384558260 cites W2127892610 @default.
- W4384558260 cites W2210453860 @default.
- W4384558260 cites W2345602314 @default.
- W4384558260 cites W2403400382 @default.
- W4384558260 cites W2511951051 @default.
- W4384558260 cites W2560258181 @default.
- W4384558260 cites W2578528809 @default.
- W4384558260 cites W2783417222 @default.
- W4384558260 cites W2800641869 @default.
- W4384558260 cites W2805209851 @default.
- W4384558260 cites W2895326014 @default.
- W4384558260 cites W2900562404 @default.
- W4384558260 cites W2914140263 @default.
- W4384558260 cites W2974056291 @default.
- W4384558260 cites W2996617264 @default.
- W4384558260 cites W2998737960 @default.
- W4384558260 cites W3005134677 @default.
- W4384558260 cites W3013052141 @default.
- W4384558260 cites W3092008673 @default.
- W4384558260 cites W3092341078 @default.
- W4384558260 cites W3128646645 @default.
- W4384558260 cites W3135828336 @default.
- W4384558260 cites W3156148127 @default.
- W4384558260 cites W4206442867 @default.
- W4384558260 cites W4309408863 @default.
- W4384558260 cites W4377206035 @default.
- W4384558260 doi "https://doi.org/10.3390/cancers15143641" @default.
- W4384558260 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37509302" @default.
- W4384558260 hasPublicationYear "2023" @default.
- W4384558260 type Work @default.
- W4384558260 citedByCount "0" @default.
- W4384558260 crossrefType "journal-article" @default.
- W4384558260 hasAuthorship W4384558260A5002878731 @default.
- W4384558260 hasAuthorship W4384558260A5009952197 @default.
- W4384558260 hasAuthorship W4384558260A5020726867 @default.
- W4384558260 hasAuthorship W4384558260A5025323978 @default.
- W4384558260 hasAuthorship W4384558260A5026506134 @default.
- W4384558260 hasAuthorship W4384558260A5035379638 @default.
- W4384558260 hasAuthorship W4384558260A5036056369 @default.
- W4384558260 hasAuthorship W4384558260A5078775589 @default.
- W4384558260 hasAuthorship W4384558260A5085503842 @default.
- W4384558260 hasAuthorship W4384558260A5086357025 @default.
- W4384558260 hasAuthorship W4384558260A5087712560 @default.
- W4384558260 hasAuthorship W4384558260A5089787707 @default.
- W4384558260 hasAuthorship W4384558260A5090779125 @default.
- W4384558260 hasAuthorship W4384558260A5090876871 @default.
- W4384558260 hasBestOaLocation W43845582601 @default.
- W4384558260 hasConcept C123982805 @default.
- W4384558260 hasConcept C126322002 @default.
- W4384558260 hasConcept C137061746 @default.
- W4384558260 hasConcept C143998085 @default.
- W4384558260 hasConcept C167672396 @default.
- W4384558260 hasConcept C202751555 @default.
- W4384558260 hasConcept C203014093 @default.
- W4384558260 hasConcept C2776090121 @default.
- W4384558260 hasConcept C2776694085 @default.
- W4384558260 hasConcept C2777546739 @default.
- W4384558260 hasConcept C2778424827 @default.
- W4384558260 hasConcept C2778822529 @default.
- W4384558260 hasConcept C2781197716 @default.
- W4384558260 hasConcept C2994415158 @default.
- W4384558260 hasConcept C553184892 @default.
- W4384558260 hasConcept C55493867 @default.
- W4384558260 hasConcept C71924100 @default.
- W4384558260 hasConcept C79484868 @default.
- W4384558260 hasConcept C86803240 @default.
- W4384558260 hasConcept C8891405 @default.
- W4384558260 hasConcept C90924648 @default.
- W4384558260 hasConceptScore W4384558260C123982805 @default.
- W4384558260 hasConceptScore W4384558260C126322002 @default.
- W4384558260 hasConceptScore W4384558260C137061746 @default.
- W4384558260 hasConceptScore W4384558260C143998085 @default.