Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384558571> ?p ?o ?g. }
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- W4384558571 abstract "Abstract Ferroptosis is a new form of programmed cell death, which is characterized by the iron-dependent accumulation of lipid peroxidation and increase of ROS, resulting in oxidative stress and cell death. Iron, lipid, and multiple signaling pathways precisely control the occurrence and implementation of ferroptosis. The pathways mainly include Nrf2/HO-1 signaling pathway, p62/Keap1/Nrf2 signaling pathway. Activating p62/Keap1/Nrf2 signaling pathway inhibits ferroptosis. Nrf2/HO-1 signaling pathway promotes ferroptosis. Furthermore, some factors also participate in the occurrence of ferroptosis under hypoxia, such as HIF-1, NCOA4, DMT1. Meanwhile, ferroptosis is related with hypoxia-related diseases, such as MIRI, cancers, and AKI. Accordingly, ferroptosis appears to be a therapeutic target for hypoxia-related diseases." @default.
- W4384558571 created "2023-07-18" @default.
- W4384558571 creator A5031734733 @default.
- W4384558571 creator A5041080871 @default.
- W4384558571 creator A5042079773 @default.
- W4384558571 creator A5045706325 @default.
- W4384558571 creator A5055958896 @default.
- W4384558571 creator A5071599573 @default.
- W4384558571 creator A5092486225 @default.
- W4384558571 date "2023-07-17" @default.
- W4384558571 modified "2023-09-25" @default.
- W4384558571 title "The Mechanisms of Ferroptosis Under Hypoxia" @default.
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