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- W4384562208 abstract "To explore the value of the magnetic resonance imaging (MRI) radiomics model in predicting prostate cancer (PCa) invasion.Clinical data of 86 pathologically confirmed PCa patients in our hospital were collected, including 44 cases in the invasive group and 42 cases in the non-invasive group. All patients underwent MRI examinations, and the same parameters were used. The lesion area was manually delineated and the radiomics features were extracted from T2WI. The radiomics signature based on LASSO regression was established. Besides, logistic regression was used to identify independent clinical predictors, and a combined model incorporating the radiomics signature and independent clinical risk factor was constructed. Finally, the receiver operating characteristic curve (ROC) analysis and decision curve analysis (DCA) was performed to compare the prediction efficiency and clinical benefit of each model.A total of 867 radiomics features were obtained, and six of them were incorporated into the radiomics model. Multivariate logistic regression analysis exhibited the Gleason score as an independent clinical risk factor for PCa invasion. ROC results showed that the performance of the radiomics model was comparable to that of the clinical-radiomics model in predicting PCa invasion, and it was better than that of the single Gleason score. DCA also confirmed the considerable clinical application value of the radiomics and the clinical-radiomics models.As a simple, non-invasive, and efficient method, the radiomics model has important predictive value for PCa invasion." @default.
- W4384562208 created "2023-07-18" @default.
- W4384562208 creator A5023363049 @default.
- W4384562208 date "2023-07-01" @default.
- W4384562208 modified "2023-09-26" @default.
- W4384562208 title "Comparison of Magnetic Resonance Imaging-Based Radiomics Features with Nomogram for Prediction of Prostate Cancer Invasion" @default.
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- W4384562208 doi "https://doi.org/10.2147/ijgm.s419039" @default.
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