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• W4384570871 abstract "Abstract In clinical settings where airborne pathogens, such as Mycobacterium tuberculosis, are prevalent, they constitute an important threat to health workers and people accessing healthcare. We report key insights from a 3-year project conducted in primary healthcare clinics in South Africa, alongside other recent tuberculosis infection prevention and control (TB-IPC) research. We discuss the fragmentation of TB-IPC policies and budgets; the characteristics of individuals attending clinics with prevalent pulmonary tuberculosis; clinic congestion and patient flow; clinic design and natural ventilation; and the facility-level determinants of the implementation (or not) of TB-IPC interventions. We present modeling studies that describe the contribution of M. tuberculosis transmission in clinics to the community tuberculosis burden and economic evaluations showing that TB-IPC interventions are highly cost-effective. We argue for a set of changes to TB-IPC, including better coordination of policymaking, clinic decongestion, changes to clinic design and building regulations, and budgeting for enablers to sustain implementation of TB-IPC interventions. Additional research is needed to find the most effective means of improving the implementation of TB-IPC interventions; to develop approaches to screening for prevalent pulmonary tuberculosis that do not rely on symptoms; and to identify groups of patients that can be seen in clinic less frequently." @default.
• W4384570871 created "2023-07-18" @default.
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• W4384570871 date "2023-01-01" @default.
• W4384570871 modified "2023-10-01" @default.
• W4384570871 title "Time to change the way we think about tuberculosis infection prevention and control in health facilities: insights from recent research" @default.
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• W4384570871 doi "https://doi.org/10.1017/ash.2023.192" @default.
• W4384570871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37502244" @default.
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