Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384575982> ?p ?o ?g. }
- W4384575982 endingPage "100687" @default.
- W4384575982 startingPage "100687" @default.
- W4384575982 abstract "Understanding and quantifying the differences in disease development in different socioeconomic groups of people across the lifespan is important for planning healthcare and preventive services. The study aimed to measure chronic disease accrual, and examine the differences in time to individual morbidities, multimorbidity, and mortality between socioeconomic groups in Wales, UK.Population-wide electronic linked cohort study, following Welsh residents for up to 20 years (2000-2019). Chronic disease diagnoses were obtained from general practice and hospitalisation records using the CALIBER disease phenotype register. Multi-state models were used to examine trajectories of accrual of 132 diseases and mortality, adjusted for sex, age and area-level deprivation. Restricted mean survival time was calculated to measure time spent free of chronic disease(s) or mortality between socioeconomic groups.In total, 965,905 individuals aged 5-104 were included, from a possible 2.9 m individuals following a 5-year clearance period, with an average follow-up of 13.2 years (12.7 million person-years). Some 673,189 (69.7%) individuals developed at least one chronic disease or died within the study period. From ages 10 years upwards, the individuals living in the most deprived areas consistently experienced reduced time between health states, demonstrating accelerated transitions to first and subsequent morbidities and death compared to their demographic equivalent living in the least deprived areas. The largest difference were observed in 10 and 20 year old males developing multimorbidity (-0.45 years (99% CI: -0.45, -0.44)) and in 70 year old males dying after developing multimorbidity (-1.98 years (99% CI: -2.01, -1.95)).This study adds to the existing literature on health inequalities by demonstrating that individuals living in more deprived areas consistently experience accelerated time to diagnosis of chronic disease and death across all ages, accounting for competing risks.UK Medical Research Council, Health Data Research UK, and Administrative Data Research Wales." @default.
- W4384575982 created "2023-07-18" @default.
- W4384575982 creator A5000929297 @default.
- W4384575982 creator A5004828576 @default.
- W4384575982 creator A5005113090 @default.
- W4384575982 creator A5010592366 @default.
- W4384575982 creator A5011025189 @default.
- W4384575982 creator A5031102856 @default.
- W4384575982 creator A5033011934 @default.
- W4384575982 creator A5045302758 @default.
- W4384575982 creator A5054234296 @default.
- W4384575982 creator A5054578676 @default.
- W4384575982 creator A5055643609 @default.
- W4384575982 creator A5059494163 @default.
- W4384575982 creator A5060828463 @default.
- W4384575982 creator A5067907002 @default.
- W4384575982 creator A5068910485 @default.
- W4384575982 creator A5072786084 @default.
- W4384575982 creator A5073010916 @default.
- W4384575982 creator A5074388922 @default.
- W4384575982 creator A5075519183 @default.
- W4384575982 creator A5077662883 @default.
- W4384575982 creator A5087171949 @default.
- W4384575982 creator A5087628519 @default.
- W4384575982 date "2023-09-01" @default.
- W4384575982 modified "2023-09-27" @default.
- W4384575982 title "Trajectories in chronic disease accrual and mortality across the lifespan in Wales, UK (2005–2019), by area deprivation profile: linked electronic health records cohort study on 965,905 individuals" @default.
- W4384575982 cites W2056139481 @default.
- W4384575982 cites W2060363472 @default.
- W4384575982 cites W2072013249 @default.
- W4384575982 cites W2102441729 @default.
- W4384575982 cites W2108510859 @default.
- W4384575982 cites W2113954266 @default.
- W4384575982 cites W2135139509 @default.
- W4384575982 cites W2150272490 @default.
- W4384575982 cites W2154117702 @default.
- W4384575982 cites W2804186780 @default.
- W4384575982 cites W2919188527 @default.
- W4384575982 cites W2943107869 @default.
- W4384575982 cites W2944890781 @default.
- W4384575982 cites W2980919873 @default.
- W4384575982 cites W2994633471 @default.
- W4384575982 cites W3003676629 @default.
- W4384575982 cites W3036649375 @default.
- W4384575982 cites W3081999921 @default.
- W4384575982 cites W3087172875 @default.
- W4384575982 cites W3105604255 @default.
- W4384575982 cites W3121175102 @default.
- W4384575982 cites W3128197370 @default.
- W4384575982 cites W3178304002 @default.
- W4384575982 cites W3210626373 @default.
- W4384575982 cites W4210887492 @default.
- W4384575982 cites W4243859617 @default.
- W4384575982 cites W4282974350 @default.
- W4384575982 cites W4291007860 @default.
- W4384575982 cites W4291514176 @default.
- W4384575982 cites W4298615154 @default.
- W4384575982 cites W4316036383 @default.
- W4384575982 cites W7256561 @default.
- W4384575982 doi "https://doi.org/10.1016/j.lanepe.2023.100687" @default.
- W4384575982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37520147" @default.
- W4384575982 hasPublicationYear "2023" @default.
- W4384575982 type Work @default.
- W4384575982 citedByCount "0" @default.
- W4384575982 crossrefType "journal-article" @default.
- W4384575982 hasAuthorship W4384575982A5000929297 @default.
- W4384575982 hasAuthorship W4384575982A5004828576 @default.
- W4384575982 hasAuthorship W4384575982A5005113090 @default.
- W4384575982 hasAuthorship W4384575982A5010592366 @default.
- W4384575982 hasAuthorship W4384575982A5011025189 @default.
- W4384575982 hasAuthorship W4384575982A5031102856 @default.
- W4384575982 hasAuthorship W4384575982A5033011934 @default.
- W4384575982 hasAuthorship W4384575982A5045302758 @default.
- W4384575982 hasAuthorship W4384575982A5054234296 @default.
- W4384575982 hasAuthorship W4384575982A5054578676 @default.
- W4384575982 hasAuthorship W4384575982A5055643609 @default.
- W4384575982 hasAuthorship W4384575982A5059494163 @default.
- W4384575982 hasAuthorship W4384575982A5060828463 @default.
- W4384575982 hasAuthorship W4384575982A5067907002 @default.
- W4384575982 hasAuthorship W4384575982A5068910485 @default.
- W4384575982 hasAuthorship W4384575982A5072786084 @default.
- W4384575982 hasAuthorship W4384575982A5073010916 @default.
- W4384575982 hasAuthorship W4384575982A5074388922 @default.
- W4384575982 hasAuthorship W4384575982A5075519183 @default.
- W4384575982 hasAuthorship W4384575982A5077662883 @default.
- W4384575982 hasAuthorship W4384575982A5087171949 @default.
- W4384575982 hasAuthorship W4384575982A5087628519 @default.
- W4384575982 hasBestOaLocation W43845759821 @default.
- W4384575982 hasConcept C126322002 @default.
- W4384575982 hasConcept C133925201 @default.
- W4384575982 hasConcept C144024400 @default.
- W4384575982 hasConcept C147077947 @default.
- W4384575982 hasConcept C149923435 @default.
- W4384575982 hasConcept C201903717 @default.
- W4384575982 hasConcept C2779134260 @default.
- W4384575982 hasConcept C2908647359 @default.
- W4384575982 hasConcept C2909273474 @default.
- W4384575982 hasConcept C71924100 @default.