Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384616091> ?p ?o ?g. }
- W4384616091 abstract "Introduction Capparis spinosa L. fruits as edible and medicinal plant, has anti-inflammatory activities. The different morphological characteristics of C. spinosa fruits from Ili, Turpan, and Karamay may affect their anti-inflammatory components and functions. Methods The anti-inflammatory activity of C. spinosa fruit was assessed using an LPS-induced inflammatory cell model. Furthermore, the differences in anti-inflammatory compounds were analyzed by metabolome and RNA-seq. Additionally, the anti-inflammatory mechanism was elucidated using network pharmacology. Results In the study, we found that the 95% ethanol extracts (CSE) obtained from the three kinds of fruits showed remarkable anti-inflammatory effects both in vivo and in vitro . However, the CSE derived from Ili fruits significantly reduced CD86 levels on DCs. As a result of metabolomic analysis, the metabolic profiles of Ili fruits differed significantly from those of the other two habitats, which were consistent with transcriptome analysis. A total of 15 compounds exhibiting anti-inflammatory activity were subjected to screening, revealing a greater accumulation of flavonoids in the Turpan and Karamay districts. Notably, phenolic compounds were identified as the principal anti-inflammatory components in C. spinosa . Conclusion There were significant differences in the morphology, metabolites, transcriptional levels, and anti-inflammatory activity of C. spinosa from the three districts." @default.
- W4384616091 created "2023-07-18" @default.
- W4384616091 creator A5000547535 @default.
- W4384616091 creator A5015860537 @default.
- W4384616091 creator A5032986788 @default.
- W4384616091 creator A5048145081 @default.
- W4384616091 creator A5049683845 @default.
- W4384616091 creator A5057693244 @default.
- W4384616091 creator A5061706893 @default.
- W4384616091 creator A5065282137 @default.
- W4384616091 creator A5082188880 @default.
- W4384616091 date "2023-07-17" @default.
- W4384616091 modified "2023-09-25" @default.
- W4384616091 title "Quality variation and biosynthesis of anti-inflammatory compounds for Capparis spinosa based on the metabolome and transcriptome analysis" @default.
- W4384616091 cites W1220296189 @default.
- W4384616091 cites W1972019946 @default.
- W4384616091 cites W1999039486 @default.
- W4384616091 cites W2000301314 @default.
- W4384616091 cites W2001190528 @default.
- W4384616091 cites W2007499788 @default.
- W4384616091 cites W2050210663 @default.
- W4384616091 cites W2101260775 @default.
- W4384616091 cites W2113030021 @default.
- W4384616091 cites W2145460854 @default.
- W4384616091 cites W2192401779 @default.
- W4384616091 cites W2253282997 @default.
- W4384616091 cites W2310732586 @default.
- W4384616091 cites W2482487219 @default.
- W4384616091 cites W2504484095 @default.
- W4384616091 cites W2536268199 @default.
- W4384616091 cites W2546301035 @default.
- W4384616091 cites W2568873509 @default.
- W4384616091 cites W2582359899 @default.
- W4384616091 cites W2593850994 @default.
- W4384616091 cites W2615153455 @default.
- W4384616091 cites W2783019295 @default.
- W4384616091 cites W2790664666 @default.
- W4384616091 cites W2799613805 @default.
- W4384616091 cites W2808277822 @default.
- W4384616091 cites W2889267407 @default.
- W4384616091 cites W2891205856 @default.
- W4384616091 cites W2967777247 @default.
- W4384616091 cites W2967956214 @default.
- W4384616091 cites W2976444924 @default.
- W4384616091 cites W2977998123 @default.
- W4384616091 cites W2996071070 @default.
- W4384616091 cites W3005311672 @default.
- W4384616091 cites W3007673311 @default.
- W4384616091 cites W3034609706 @default.
- W4384616091 cites W3043113447 @default.
- W4384616091 cites W3043236841 @default.
- W4384616091 cites W3092351703 @default.
- W4384616091 doi "https://doi.org/10.3389/fpls.2023.1224073" @default.
- W4384616091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37528974" @default.
- W4384616091 hasPublicationYear "2023" @default.
- W4384616091 type Work @default.
- W4384616091 citedByCount "0" @default.
- W4384616091 crossrefType "journal-article" @default.
- W4384616091 hasAuthorship W4384616091A5000547535 @default.
- W4384616091 hasAuthorship W4384616091A5015860537 @default.
- W4384616091 hasAuthorship W4384616091A5032986788 @default.
- W4384616091 hasAuthorship W4384616091A5048145081 @default.
- W4384616091 hasAuthorship W4384616091A5049683845 @default.
- W4384616091 hasAuthorship W4384616091A5057693244 @default.
- W4384616091 hasAuthorship W4384616091A5061706893 @default.
- W4384616091 hasAuthorship W4384616091A5065282137 @default.
- W4384616091 hasAuthorship W4384616091A5082188880 @default.
- W4384616091 hasBestOaLocation W43846160911 @default.
- W4384616091 hasConcept C104317684 @default.
- W4384616091 hasConcept C135870905 @default.
- W4384616091 hasConcept C150194340 @default.
- W4384616091 hasConcept C162317418 @default.
- W4384616091 hasConcept C21565614 @default.
- W4384616091 hasConcept C2777278459 @default.
- W4384616091 hasConcept C2778905741 @default.
- W4384616091 hasConcept C2779703632 @default.
- W4384616091 hasConcept C2779729912 @default.
- W4384616091 hasConcept C2909605514 @default.
- W4384616091 hasConcept C55493867 @default.
- W4384616091 hasConcept C556039675 @default.
- W4384616091 hasConcept C59822182 @default.
- W4384616091 hasConcept C60644358 @default.
- W4384616091 hasConcept C71924100 @default.
- W4384616091 hasConcept C86803240 @default.
- W4384616091 hasConcept C98274493 @default.
- W4384616091 hasConceptScore W4384616091C104317684 @default.
- W4384616091 hasConceptScore W4384616091C135870905 @default.
- W4384616091 hasConceptScore W4384616091C150194340 @default.
- W4384616091 hasConceptScore W4384616091C162317418 @default.
- W4384616091 hasConceptScore W4384616091C21565614 @default.
- W4384616091 hasConceptScore W4384616091C2777278459 @default.
- W4384616091 hasConceptScore W4384616091C2778905741 @default.
- W4384616091 hasConceptScore W4384616091C2779703632 @default.
- W4384616091 hasConceptScore W4384616091C2779729912 @default.
- W4384616091 hasConceptScore W4384616091C2909605514 @default.
- W4384616091 hasConceptScore W4384616091C55493867 @default.
- W4384616091 hasConceptScore W4384616091C556039675 @default.
- W4384616091 hasConceptScore W4384616091C59822182 @default.
- W4384616091 hasConceptScore W4384616091C60644358 @default.
- W4384616091 hasConceptScore W4384616091C71924100 @default.