FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384661949> ?p ?o ?g. }

• W4384661949 endingPage "9" @default.
• W4384661949 startingPage "1" @default.
• W4384661949 abstract "Background: Traditional health economic evaluations of antimicrobials currently underestimate their value to wider society. They can be supplemented by additional value elements including insurance value, which captures the value of an antimicrobial in preventing or mitigating impacts of adverse risk events. Despite being commonplace in other sectors, constituents of the impacts and approaches for estimating insurance value have not been investigated. Objectives: This study assessed the insurance value of a novel gram-negative antimicrobial from operational healthcare, wider population health, productivity, and informal care perspectives. Methods: A novel mixed-methods approach was used to model insurance value in the United Kingdom: (1) literature review and multidisciplinary expert workshops to identify risk events for 4 relevant scenarios: ward closures, unavoidable shortage of conventional antimicrobials, viral respiratory pandemics, and catastrophic antimicrobial resistance (AMR); (2) parameterizing mitigable costs and frequencies of risk events across perspectives and scenarios; (3) estimating insurance value through a Monte Carlo simulation model for extreme events and a dynamic disease transmission model. Results: The mean insurance value across all scenarios and perspectives over 10 years in the UK was £718 million, should AMR remain unchanged, where only £134 million related to operational healthcare costs. It would be 50%-70% higher if AMR steadily increased or if a more risk-averse view (1-in-10 year downside) of future events is taken. Discussion: The overall insurance value if AMR remains at current levels (a conservative projection), is over 5 times greater than insurance value from just the operational healthcare costs perspective, traditionally the sole perspective used in health budgeting. Insurance value was generally larger for nationwide or universal (catastrophic AMR, pandemic, and conventional antimicrobial shortages) rather than localized (ward closure) scenarios, across perspectives. Components of this insurance value match previously published estimates of operational costs and mortality impacts. Conclusions: Insurance value of novel antimicrobials can be systematically modeled and substantially augments their traditional health economic value in normal circumstances. These approaches are generalizable to similar health interventions and form a framework for health systems and governments to capture broader value in health technology assessments, improve healthcare access, and increase resilience by planning for adverse scenarios." @default.
• W4384661949 created "2023-07-20" @default.
• W4384661949 creator A5022193236 @default.
• W4384661949 creator A5027672611 @default.
• W4384661949 creator A5045543520 @default.
• W4384661949 creator A5050198943 @default.
• W4384661949 creator A5050792181 @default.
• W4384661949 creator A5053132864 @default.
• W4384661949 creator A5054758734 @default.
• W4384661949 creator A5073057602 @default.
• W4384661949 creator A5079462573 @default.
• W4384661949 creator A5080112798 @default.
• W4384661949 date "2023-07-18" @default.
• W4384661949 modified "2023-09-26" @default.
• W4384661949 title "An Insurance Value Modeling Approach That Captures the Wider Value of a Novel Antimicrobial to Health Systems, Patients, and the Population" @default.
• W4384661949 cites W1561263655 @default.
• W4384661949 cites W2012195871 @default.
• W4384661949 cites W2786664152 @default.
• W4384661949 cites W2789154607 @default.
• W4384661949 cites W2890373468 @default.
• W4384661949 cites W2905201566 @default.
• W4384661949 cites W3014421200 @default.
• W4384661949 cites W3023977941 @default.
• W4384661949 cites W3119407584 @default.
• W4384661949 cites W3128602895 @default.
• W4384661949 cites W3130240926 @default.
• W4384661949 cites W3151320439 @default.
• W4384661949 cites W4206677002 @default.
• W4384661949 cites W4230353808 @default.
• W4384661949 doi "https://doi.org/10.36469/jheor.2023.75206" @default.
• W4384661949 hasPublicationYear "2023" @default.
• W4384661949 type Work @default.
• W4384661949 citedByCount "1" @default.
• W4384661949 countsByYear W43846619492023 @default.
• W4384661949 crossrefType "journal-article" @default.
• W4384661949 hasAuthorship W4384661949A5022193236 @default.
• W4384661949 hasAuthorship W4384661949A5027672611 @default.
• W4384661949 hasAuthorship W4384661949A5045543520 @default.
• W4384661949 hasAuthorship W4384661949A5050198943 @default.
• W4384661949 hasAuthorship W4384661949A5050792181 @default.
• W4384661949 hasAuthorship W4384661949A5053132864 @default.
• W4384661949 hasAuthorship W4384661949A5054758734 @default.
• W4384661949 hasAuthorship W4384661949A5073057602 @default.
• W4384661949 hasAuthorship W4384661949A5079462573 @default.
• W4384661949 hasAuthorship W4384661949A5080112798 @default.
• W4384661949 hasBestOaLocation W43846619491 @default.
• W4384661949 hasConcept C112930515 @default.
• W4384661949 hasConcept C119857082 @default.
• W4384661949 hasConcept C144133560 @default.
• W4384661949 hasConcept C160735492 @default.
• W4384661949 hasConcept C162118730 @default.
• W4384661949 hasConcept C162324750 @default.
• W4384661949 hasConcept C2776291640 @default.
• W4384661949 hasConcept C2908647359 @default.
• W4384661949 hasConcept C41008148 @default.
• W4384661949 hasConcept C50522688 @default.
• W4384661949 hasConcept C71924100 @default.
• W4384661949 hasConcept C99454951 @default.
• W4384661949 hasConceptScore W4384661949C112930515 @default.
• W4384661949 hasConceptScore W4384661949C119857082 @default.
• W4384661949 hasConceptScore W4384661949C144133560 @default.
• W4384661949 hasConceptScore W4384661949C160735492 @default.
• W4384661949 hasConceptScore W4384661949C162118730 @default.
• W4384661949 hasConceptScore W4384661949C162324750 @default.
• W4384661949 hasConceptScore W4384661949C2776291640 @default.
• W4384661949 hasConceptScore W4384661949C2908647359 @default.
• W4384661949 hasConceptScore W4384661949C41008148 @default.
• W4384661949 hasConceptScore W4384661949C50522688 @default.
• W4384661949 hasConceptScore W4384661949C71924100 @default.
• W4384661949 hasConceptScore W4384661949C99454951 @default.
• W4384661949 hasLocation W43846619491 @default.
• W4384661949 hasOpenAccess W4384661949 @default.
• W4384661949 hasPrimaryLocation W43846619491 @default.
• W4384661949 hasRelatedWork W1507001008 @default.
• W4384661949 hasRelatedWork W2567126684 @default.
• W4384661949 hasRelatedWork W2899084033 @default.
• W4384661949 hasRelatedWork W3000832017 @default.
• W4384661949 hasRelatedWork W3042572556 @default.
• W4384661949 hasRelatedWork W3152006065 @default.
• W4384661949 hasRelatedWork W4200392185 @default.
• W4384661949 hasRelatedWork W4221081523 @default.
• W4384661949 hasRelatedWork W4324353450 @default.
• W4384661949 hasRelatedWork W65187918 @default.
• W4384661949 isParatext "false" @default.
• W4384661949 isRetracted "false" @default.
• W4384661949 workType "article" @default.