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- W4384663492 abstract "Abstract The spontaneous retrieval deficit (SRD) hypothesis argues that individuals in the preclinical stages of Alzheimer’s disease (AD) are particularly impaired in spontaneous retrieval, which manifests in reduced mind-wandering. Our main purpose was to provide novel evidence to support the SRD hypothesis by investigating, for the first time, the relationship between mind-wandering and periodontitis, the latter being the risk factor for AD. The second objective was to address the lack of deeper understanding of the relationship between oral health and specific cognitive abilities by investigating whether periodontitis would be primarily associated with memory. Sixty community-dwelling dementia-free older adults completed neuropsychological tests that focused on various cognitive abilities and a computerised task, during which mind-wandering was evaluated. Periodontal health was assessed subjectively, and through an oral examination by a qualified dentist that focused on visible periodontitis-related changes in gingival tissues and the number of periodontitis bacteria. In line with our predictions, objective and subjective symptoms of poorer periodontal health were associated with less mind-wandering, providing further support for the SRD hypothesis. Again in line with predictions, poorer periodontal health was associated with worse episodic memory, with no relationship between periodontitis and the measure targeting various cognitive abilities, from which memory was excluded." @default.
- W4384663492 created "2023-07-20" @default.
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- W4384663492 date "2023-07-18" @default.
- W4384663492 modified "2023-09-25" @default.
- W4384663492 title "Investigating the relationship between periodontitis and specific memory processes in the search for cognitive markers of Alzheimer’s disease risk" @default.
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- W4384663492 doi "https://doi.org/10.1038/s41598-023-38674-w" @default.
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