Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384663652> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4384663652 endingPage "6" @default.
- W4384663652 startingPage "1" @default.
- W4384663652 abstract "Teriparatide (TPD) is an osteoanabolic agent used in patients with high osteoporotic fracture risk. Predictors of therapeutic response to TPD in real-life setting are not well characterised. This study investigated the influence of previous antiresorptive therapy, age and other patient characteristics on the skeletal response to TPD.Retrospective study at the metabolic bone clinic, University Hospitals Leuven, Belgium. Patients with osteoporosis and a high fracture burden received TPD for 9-18 months. Bone mineral density (BMD) was measured at baseline, 9 and 18 months at lumbar spine (LS), femoral neck (FN) and total hip (TH).BMD at LS increased at 9 months (change mean (standard error) 6.8 % (0.7) p < 0.001) and at 18 months (8.0 % (0.9) p < 0.001), while BMD at FN and TH did not change significantly. Non-response in BMD change at the LS was seen with prior denosumab use (odds ratio 0.21, 95% confidence interval (CI) 0.049-0.912, p = 0.037). Changes in BMD at TH were significantly greater in younger patients and in patients with a lower baseline BMD.TPD-induced changes in BMD at TH might depend on age and baseline BMD and at LS on prior denosumab use. The results suggest that these factors may be relevant for clinical decision making when initiating TPD treatment, although larger studies are needed to confirm these findings." @default.
- W4384663652 created "2023-07-20" @default.
- W4384663652 creator A5011462753 @default.
- W4384663652 creator A5024945442 @default.
- W4384663652 creator A5045120942 @default.
- W4384663652 creator A5074874628 @default.
- W4384663652 creator A5080465451 @default.
- W4384663652 date "2023-07-19" @default.
- W4384663652 modified "2023-10-18" @default.
- W4384663652 title "Skeletal response to teriparatide in real-life setting: effects of age, baseline bone density and prior denosumab use" @default.
- W4384663652 cites W1554395215 @default.
- W4384663652 cites W1911703092 @default.
- W4384663652 cites W1989880575 @default.
- W4384663652 cites W2019214663 @default.
- W4384663652 cites W2037210676 @default.
- W4384663652 cites W2041578222 @default.
- W4384663652 cites W2059670446 @default.
- W4384663652 cites W2079963757 @default.
- W4384663652 cites W2083011022 @default.
- W4384663652 cites W2096303371 @default.
- W4384663652 cites W2103502150 @default.
- W4384663652 cites W2108106130 @default.
- W4384663652 cites W2330437979 @default.
- W4384663652 cites W2335178464 @default.
- W4384663652 cites W2346932117 @default.
- W4384663652 cites W2585701238 @default.
- W4384663652 cites W2606663768 @default.
- W4384663652 cites W2797982330 @default.
- W4384663652 cites W2893028662 @default.
- W4384663652 cites W2921760854 @default.
- W4384663652 cites W2966161559 @default.
- W4384663652 cites W3006754541 @default.
- W4384663652 cites W3024104583 @default.
- W4384663652 cites W3044275622 @default.
- W4384663652 cites W4210419475 @default.
- W4384663652 cites W4210583963 @default.
- W4384663652 cites W4220786017 @default.
- W4384663652 doi "https://doi.org/10.1080/17843286.2023.2238375" @default.
- W4384663652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37466144" @default.
- W4384663652 hasPublicationYear "2023" @default.
- W4384663652 type Work @default.
- W4384663652 citedByCount "0" @default.
- W4384663652 crossrefType "journal-article" @default.
- W4384663652 hasAuthorship W4384663652A5011462753 @default.
- W4384663652 hasAuthorship W4384663652A5024945442 @default.
- W4384663652 hasAuthorship W4384663652A5045120942 @default.
- W4384663652 hasAuthorship W4384663652A5074874628 @default.
- W4384663652 hasAuthorship W4384663652A5080465451 @default.
- W4384663652 hasConcept C126322002 @default.
- W4384663652 hasConcept C126894567 @default.
- W4384663652 hasConcept C141071460 @default.
- W4384663652 hasConcept C156957248 @default.
- W4384663652 hasConcept C2775854910 @default.
- W4384663652 hasConcept C2776286101 @default.
- W4384663652 hasConcept C2776541429 @default.
- W4384663652 hasConcept C2776886416 @default.
- W4384663652 hasConcept C2777308945 @default.
- W4384663652 hasConcept C2779329777 @default.
- W4384663652 hasConcept C44249647 @default.
- W4384663652 hasConcept C71924100 @default.
- W4384663652 hasConceptScore W4384663652C126322002 @default.
- W4384663652 hasConceptScore W4384663652C126894567 @default.
- W4384663652 hasConceptScore W4384663652C141071460 @default.
- W4384663652 hasConceptScore W4384663652C156957248 @default.
- W4384663652 hasConceptScore W4384663652C2775854910 @default.
- W4384663652 hasConceptScore W4384663652C2776286101 @default.
- W4384663652 hasConceptScore W4384663652C2776541429 @default.
- W4384663652 hasConceptScore W4384663652C2776886416 @default.
- W4384663652 hasConceptScore W4384663652C2777308945 @default.
- W4384663652 hasConceptScore W4384663652C2779329777 @default.
- W4384663652 hasConceptScore W4384663652C44249647 @default.
- W4384663652 hasConceptScore W4384663652C71924100 @default.
- W4384663652 hasLocation W43846636521 @default.
- W4384663652 hasLocation W43846636522 @default.
- W4384663652 hasOpenAccess W4384663652 @default.
- W4384663652 hasPrimaryLocation W43846636521 @default.
- W4384663652 hasRelatedWork W1911703092 @default.
- W4384663652 hasRelatedWork W2089035363 @default.
- W4384663652 hasRelatedWork W2592154370 @default.
- W4384663652 hasRelatedWork W2626568597 @default.
- W4384663652 hasRelatedWork W2726184882 @default.
- W4384663652 hasRelatedWork W3123605326 @default.
- W4384663652 hasRelatedWork W3202087077 @default.
- W4384663652 hasRelatedWork W4289745584 @default.
- W4384663652 hasRelatedWork W4381681332 @default.
- W4384663652 hasRelatedWork W2186476187 @default.
- W4384663652 isParatext "false" @default.
- W4384663652 isRetracted "false" @default.
- W4384663652 workType "article" @default.