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- W4384666201 abstract "Juvenile hormone (JH) plays a vital role in the growth, development, and reproduction of insects and other arthropods. Previous experiments have suggested that BmFAMeT6 could affect the duration of the silk moth’s larval stage. In this study, we established the BmFAMeT6 overexpression strain and BmFAMeT6 knockout strain using the GAL4/UAS binary hybrid system and CRISPR/Cas 9 system, respectively, and found that the larval stage of the overexpression strain was shorter, while the knockout strain was longer. Our results exhibited that both the JH titers and BmKr-h1 levels in the larvae of the third instar were reduced significantly by BmFAMeT6 overexpression, but were increased obviously by BmFAMeT6 knockout. In addition, injection of farnesoic acid induced changes in the JH I and JH II levels in the hemolymphs of larvae. This study is the first to directly reveal the role of BmFAMeT6 in the regulation of insect JH titers and the relationship between farnesoic acid and JH (JH I and JH II). This provides a new perspective on regulating the growth and development of insects such as Bombyx mori." @default.
- W4384666201 created "2023-07-20" @default.
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- W4384666201 date "2023-07-17" @default.
- W4384666201 modified "2023-09-30" @default.
- W4384666201 title "Possible Regulation of Larval Juvenile Hormone Titers in Bombyx mori by BmFAMeT6" @default.
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- W4384666201 doi "https://doi.org/10.3390/insects14070644" @default.
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