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- W4384695329 endingPage "401" @default.
- W4384695329 startingPage "401" @default.
- W4384695329 abstract "Cylindrospermopsin (CYN) is a freshwater algal toxin produced during the proliferation of harmful cyanobacteria, known as cyanobacterial algal blooms (cyano-HABs). Recently, the effects of global warming have facilitated the growth of cyano-HABs, leading to their worldwide occurrence and an increase in toxin-related damage to aquatic ecosystems. CYN is known to exhibit strong cell toxicity upon ingestion, inhibiting protein synthesis and glutathione production and, ultimately, leading to cell death. In addition to cell toxicity, CYN exhibits skin toxicity, genotoxicity, and hepatotoxicity. It can also affect other organs, such as the kidneys (causing tubular necrosis), thymus (causing atrophy), and heart (causing pericardial and myocardial hemorrhage). The standard method used for CYN detection to date, enzyme-linked immunosorbent assay (ELISA), has several drawbacks: it is complex, time-consuming, and requires trained researchers. Recently, biosensors have been shown to offer numerous advantages, such as their simplicity, portability, and rapidity, making them suitable for onsite applications. Consequently, recent studies have actively explored the latest biosensor-based technologies for CYN detection. This review discusses the recent advances in CYN detection platforms that utilize several types of biosensors." @default.
- W4384695329 created "2023-07-20" @default.
- W4384695329 creator A5021149071 @default.
- W4384695329 creator A5044722349 @default.
- W4384695329 creator A5055188159 @default.
- W4384695329 creator A5064167751 @default.
- W4384695329 creator A5068648230 @default.
- W4384695329 creator A5072434509 @default.
- W4384695329 date "2023-07-18" @default.
- W4384695329 modified "2023-09-26" @default.
- W4384695329 title "Recent Advances in Cyanobacterial Cytotoxin Biosensors Focused on Cylindrospermopsin" @default.
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