FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384696154> ?p ?o ?g. }

• W4384696154 abstract "As the world emerges from the COVID-19 pandemic, there is an urgent need to understand patient factors that may be used to predict the occurrence of severe cases and patient mortality. Approximately 20% of SARS-CoV-2 infections lead to acute respiratory distress syndrome caused by the harmful actions of inflammatory mediators. Patients with severe COVID-19 are often afflicted with neurologic symptoms, and individuals with pre-existing neurodegenerative disease have an increased risk of severe COVID-19. Although collectively, these observations point to a bidirectional relationship between severe COVID-19 and neurologic disorders, little is known about the underlying mechanisms. Here, we analyzed the electronic health records of 471 patients with severe COVID-19 to identify clinical characteristics most predictive of mortality. Feature discovery was conducted by training a regularized logistic regression classifier that serves as a machine-learning model with an embedded feature selection capability. SHAP analysis using the trained classifier revealed that a small ensemble of readily observable clinical features, including characteristics associated with cognitive impairment, could predict in-hospital mortality with an accuracy greater than 0.85 (expressed as the area under the ROC curve of the classifier). These findings have important implications for the prioritization of clinical measures used to identify patients with COVID-19 (and, potentially, other forms of acute respiratory distress syndrome) having an elevated risk of death." @default.
• W4384696154 created "2023-07-20" @default.
• W4384696154 creator A5005391133 @default.
• W4384696154 creator A5019202832 @default.
• W4384696154 creator A5019813933 @default.
• W4384696154 creator A5034713503 @default.
• W4384696154 creator A5052631324 @default.
• W4384696154 creator A5059342685 @default.
• W4384696154 creator A5067612292 @default.
• W4384696154 date "2023-07-18" @default.
• W4384696154 modified "2023-09-27" @default.
• W4384696154 title "Identification of predictive patient characteristics for assessing the probability of COVID-19 in-hospital mortality" @default.
• W4384696154 cites W1562353621 @default.
• W4384696154 cites W1767942727 @default.
• W4384696154 cites W1965180923 @default.
• W4384696154 cites W1996386126 @default.
• W4384696154 cites W2035820295 @default.
• W4384696154 cites W2081033553 @default.
• W4384696154 cites W2117190680 @default.
• W4384696154 cites W2122825543 @default.
• W4384696154 cites W2135046866 @default.
• W4384696154 cites W2143891888 @default.
• W4384696154 cites W2149635843 @default.
• W4384696154 cites W2417041886 @default.
• W4384696154 cites W2518039540 @default.
• W4384696154 cites W2530685584 @default.
• W4384696154 cites W2899144966 @default.
• W4384696154 cites W3024697576 @default.
• W4384696154 cites W3041868437 @default.
• W4384696154 cites W3043907733 @default.
• W4384696154 cites W3044595037 @default.
• W4384696154 cites W3088731220 @default.
• W4384696154 cites W3092436046 @default.
• W4384696154 cites W3093068007 @default.
• W4384696154 cites W3097794852 @default.
• W4384696154 cites W3102476541 @default.
• W4384696154 cites W3111349961 @default.
• W4384696154 cites W3113005448 @default.
• W4384696154 cites W3128847099 @default.
• W4384696154 cites W3138148883 @default.
• W4384696154 cites W3146613606 @default.
• W4384696154 cites W3148333766 @default.
• W4384696154 cites W3157021731 @default.
• W4384696154 cites W3174741294 @default.
• W4384696154 cites W3176923295 @default.
• W4384696154 cites W3186716861 @default.
• W4384696154 cites W3188629133 @default.
• W4384696154 cites W3198521523 @default.
• W4384696154 cites W4206979825 @default.
• W4384696154 cites W4210259711 @default.
• W4384696154 cites W4225523432 @default.
• W4384696154 cites W4232791906 @default.
• W4384696154 cites W4255455317 @default.
• W4384696154 cites W4285801262 @default.
• W4384696154 cites W4296690665 @default.
• W4384696154 cites W4303453397 @default.
• W4384696154 doi "https://doi.org/10.1101/2023.07.16.23292738" @default.
• W4384696154 hasPublicationYear "2023" @default.
• W4384696154 type Work @default.
• W4384696154 citedByCount "0" @default.
• W4384696154 crossrefType "posted-content" @default.
• W4384696154 hasAuthorship W4384696154A5005391133 @default.
• W4384696154 hasAuthorship W4384696154A5019202832 @default.
• W4384696154 hasAuthorship W4384696154A5019813933 @default.
• W4384696154 hasAuthorship W4384696154A5034713503 @default.
• W4384696154 hasAuthorship W4384696154A5052631324 @default.
• W4384696154 hasAuthorship W4384696154A5059342685 @default.
• W4384696154 hasAuthorship W4384696154A5067612292 @default.
• W4384696154 hasBestOaLocation W43846961541 @default.
• W4384696154 hasConcept C126322002 @default.
• W4384696154 hasConcept C139265228 @default.
• W4384696154 hasConcept C151956035 @default.
• W4384696154 hasConcept C162324750 @default.
• W4384696154 hasConcept C177713679 @default.
• W4384696154 hasConcept C2777615720 @default.
• W4384696154 hasConcept C2777714996 @default.
• W4384696154 hasConcept C2779134260 @default.
• W4384696154 hasConcept C2909621147 @default.
• W4384696154 hasConcept C30036603 @default.
• W4384696154 hasConcept C3008058167 @default.
• W4384696154 hasConcept C524204448 @default.
• W4384696154 hasConcept C539667460 @default.
• W4384696154 hasConcept C70410870 @default.
• W4384696154 hasConcept C71924100 @default.
• W4384696154 hasConcept C89623803 @default.
• W4384696154 hasConceptScore W4384696154C126322002 @default.
• W4384696154 hasConceptScore W4384696154C139265228 @default.
• W4384696154 hasConceptScore W4384696154C151956035 @default.
• W4384696154 hasConceptScore W4384696154C162324750 @default.
• W4384696154 hasConceptScore W4384696154C177713679 @default.
• W4384696154 hasConceptScore W4384696154C2777615720 @default.
• W4384696154 hasConceptScore W4384696154C2777714996 @default.
• W4384696154 hasConceptScore W4384696154C2779134260 @default.
• W4384696154 hasConceptScore W4384696154C2909621147 @default.
• W4384696154 hasConceptScore W4384696154C30036603 @default.
• W4384696154 hasConceptScore W4384696154C3008058167 @default.
• W4384696154 hasConceptScore W4384696154C524204448 @default.
• W4384696154 hasConceptScore W4384696154C539667460 @default.
• W4384696154 hasConceptScore W4384696154C70410870 @default.
• W4384696154 hasConceptScore W4384696154C71924100 @default.

• next