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- W4384696880 abstract "Abstract Chlorpyrifos, an organophosphate insecticide widely used to control agricultural pests, poses a significant environmental threat due to its toxicity and persistence in soil and water, causing deleterious effects on non-target organisms. In this context, our work aimed to evaluate the acute (survival) and chronic (regeneration, locomotion and reproduction) toxicity of chlorpyrifos in tropical freshwater planarians Girardia tigrina . The 48h lethal concentration (LC 50 ) of the commercial formulation, containing 480 g L − 1 of chlorpyrifos active ingredient, was determined to be 622.8 µg a.i. L − 1 for planarians. Sublethal effects were also observed, with a significant reduction in locomotion and delayed head regeneration (equal lowest observed effect concentration – LOEC = 3.88 µg a.i. L − 1 ). Our study highlight the importance of employing physiological and behavioral parameters as effective tools for assessing the ecotoxicological impact of organophosphate insecticides on non-target tropical freshwater organisms, such as G tigrinia . Overall, this study demonstrates the potential of chlorpyrifos-based insecticides to harm natural populations of freshwater planarians at environmentally relevant concentrations. The observed toxicity serves as a cause for concern, emphasizing the need for stricter regulations and careful management of chlorpyrifos usage to mitigate its deleterious effects on aquatic ecosystems. By understanding the specific impacts on non-target organisms like G. tigrina , we can make more informed decisions regarding using and regulating organophosphate insecticides, ultimately promoting sustainable agricultural practices and environmental conservation." @default.
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- W4384696880 date "2023-07-18" @default.
- W4384696880 modified "2023-10-12" @default.
- W4384696880 title "Environmentally relevant concentrations of chlorpyrifos affect behavior and physiological responses of Girardia tigrina" @default.
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- W4384696880 doi "https://doi.org/10.21203/rs.3.rs-3161598/v1" @default.
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