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- W4384697232 abstract "Abstract Background: Embryonal rhabdomyosarcoma (ERMS) of the uterine cervix is rare, but the population affected is mostly underage females. The scope of surgery has now evolved from extensive to limited, and organ-preserving surgery combined with chemotherapy is recommended to preserve the patient's fertility. However, reports of birth outcomes are rare. Case: A minor woman with cervical ERMS who underwent only an outpatient biopsy of the lesion, who had no residual lesion on subsequent multipoint cervical biopsy and who refused radical surgery or cervical conization, after which the patient received a nonclassical regimen of chemotherapy. The patient stopped the chemotherapy on her own, but the patient conceived spontaneously 16 years later with a good pregnancy outcome and no recurrence. Conclusions: This case suggests that preservation of reproductive function is often feasible in immature women with cervical EMS, and the prognosis is usually good as long as the primary tumor can be surgically removed and the lesion is free of residual disease. We also look forward to reports of subsequent growth and pregnancy outcomes in other children with reproductive tract RMS. In cervical ERMS, accurate evaluation of the disease and development of an individualized treatment plan are crucial, and the protection of reproductive function and psychological well-being deserves special attention." @default.
- W4384697232 created "2023-07-20" @default.
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- W4384697232 date "2023-07-18" @default.
- W4384697232 modified "2023-09-23" @default.
- W4384697232 title "Successful pregnancy in a female with embryonal rhabdomyosarcoma of the cervix who received biopsy and chemotherapy alone without recurrence after 16 years: a case report and literature review" @default.
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- W4384697232 doi "https://doi.org/10.21203/rs.3.rs-3131346/v1" @default.
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