FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384697954> ?p ?o ?g. }

• W4384697954 abstract "Abstract Postingestive reward contributes to acquisition of food preferences, mediated by striatal dopamine, with assessment in humans, while challenging, suggesting blunted brain responses to postingestive nutrient stimulation in obesity. To perform postingestive conditioning in humans, we used carboxymethylcellulose, a food thickener, to optimize conditions where maltodextrin, an insipid carbohydrate, was not detectable by sensory cues (n=159). In the resulting Flavour Nutrient Conditioning protocol using flavoured yoghurts, where one flavour was paired with maltodextrin (+102 Kcal, CS + ) and another with carboxymethylcellulose (+1.8 Kcal, CS - ), we found that in healthy volunteers (n=52), preference for CS + increased after conditioning, when assessed according to intake, with no effects on pleasantness scores. This protocol and [ 123 I] IBZM SPECT, to assess availability of striatal dopamine D2-like receptors (DD2lR) were applied in a clinical study (n=61) with pre-bariatric candidates with obesity, weight-stable patients after surgery, and an additional group of healthy controls. Conditioning was conserved among participants in the clinical study, and did not differ significantly between the 3 groups. However, striatal DD2lR availability was reduced in patients from the obesity group, when compared both to healthy volunteers and the surgical group. Importantly, in exploratory analyses, DD2lR availability was strongly correlated with conditioning strength, as well as a measure of restrained eating, but only in patients with gastric bypass. These results suggest that postingestive reinforcement, while conserved in obesity and after bariatric surgery, may be associated to post-surgery recovery of central dopaminergic homeostasis and to changes in feeding behaviour after gastric bypass." @default.
• W4384697954 created "2023-07-20" @default.
• W4384697954 creator A5026211332 @default.
• W4384697954 creator A5032763144 @default.
• W4384697954 creator A5038649275 @default.
• W4384697954 creator A5040837251 @default.
• W4384697954 creator A5040875950 @default.
• W4384697954 creator A5042323208 @default.
• W4384697954 creator A5060965799 @default.
• W4384697954 creator A5065148507 @default.
• W4384697954 creator A5081466098 @default.
• W4384697954 date "2023-07-18" @default.
• W4384697954 modified "2023-10-18" @default.
• W4384697954 title "Postingestive reinforcement is conserved in obesity and after bariatric surgery" @default.
• W4384697954 cites W1844037985 @default.
• W4384697954 cites W1926608970 @default.
• W4384697954 cites W1965311366 @default.
• W4384697954 cites W1975829928 @default.
• W4384697954 cites W1977176053 @default.
• W4384697954 cites W1983663661 @default.
• W4384697954 cites W1987913422 @default.
• W4384697954 cites W2010405191 @default.
• W4384697954 cites W2012865914 @default.
• W4384697954 cites W2025787676 @default.
• W4384697954 cites W2030928971 @default.
• W4384697954 cites W2038290634 @default.
• W4384697954 cites W2045236936 @default.
• W4384697954 cites W2046460103 @default.
• W4384697954 cites W2064423895 @default.
• W4384697954 cites W2066489101 @default.
• W4384697954 cites W2092703117 @default.
• W4384697954 cites W2099440512 @default.
• W4384697954 cites W2104183837 @default.
• W4384697954 cites W2115771625 @default.
• W4384697954 cites W2131605375 @default.
• W4384697954 cites W2134862918 @default.
• W4384697954 cites W2146237811 @default.
• W4384697954 cites W2148298325 @default.
• W4384697954 cites W2148493780 @default.
• W4384697954 cites W2150105411 @default.
• W4384697954 cites W2155188667 @default.
• W4384697954 cites W2164125772 @default.
• W4384697954 cites W2260747663 @default.
• W4384697954 cites W2359967437 @default.
• W4384697954 cites W2562594662 @default.
• W4384697954 cites W2576693963 @default.
• W4384697954 cites W2586936079 @default.
• W4384697954 cites W2744974021 @default.
• W4384697954 cites W2778473818 @default.
• W4384697954 cites W2797046870 @default.
• W4384697954 cites W2801938163 @default.
• W4384697954 cites W2904049876 @default.
• W4384697954 cites W2912423153 @default.
• W4384697954 cites W2960879425 @default.
• W4384697954 cites W2970461828 @default.
• W4384697954 cites W2975594824 @default.
• W4384697954 cites W3014758815 @default.
• W4384697954 cites W3016832984 @default.
• W4384697954 cites W3028542206 @default.
• W4384697954 cites W3129108554 @default.
• W4384697954 cites W3131969926 @default.
• W4384697954 cites W3180010820 @default.
• W4384697954 cites W3186914336 @default.
• W4384697954 cites W3213102631 @default.
• W4384697954 cites W4251501135 @default.
• W4384697954 cites W4253830974 @default.
• W4384697954 cites W4255671098 @default.
• W4384697954 cites W4303962382 @default.
• W4384697954 cites W4361004482 @default.
• W4384697954 cites W4380319117 @default.
• W4384697954 cites W829756699 @default.
• W4384697954 doi "https://doi.org/10.1101/2023.07.17.23292625" @default.
• W4384697954 hasPublicationYear "2023" @default.
• W4384697954 type Work @default.
• W4384697954 citedByCount "0" @default.
• W4384697954 crossrefType "posted-content" @default.
• W4384697954 hasAuthorship W4384697954A5026211332 @default.
• W4384697954 hasAuthorship W4384697954A5032763144 @default.
• W4384697954 hasAuthorship W4384697954A5038649275 @default.
• W4384697954 hasAuthorship W4384697954A5040837251 @default.
• W4384697954 hasAuthorship W4384697954A5040875950 @default.
• W4384697954 hasAuthorship W4384697954A5042323208 @default.
• W4384697954 hasAuthorship W4384697954A5060965799 @default.
• W4384697954 hasAuthorship W4384697954A5065148507 @default.
• W4384697954 hasAuthorship W4384697954A5081466098 @default.
• W4384697954 hasBestOaLocation W43846979541 @default.
• W4384697954 hasConcept C105795698 @default.
• W4384697954 hasConcept C126322002 @default.
• W4384697954 hasConcept C137183658 @default.
• W4384697954 hasConcept C142724271 @default.
• W4384697954 hasConcept C15744967 @default.
• W4384697954 hasConcept C169760540 @default.
• W4384697954 hasConcept C204787440 @default.
• W4384697954 hasConcept C2775961468 @default.
• W4384697954 hasConcept C33923547 @default.
• W4384697954 hasConcept C45262634 @default.
• W4384697954 hasConcept C511355011 @default.
• W4384697954 hasConcept C513476851 @default.
• W4384697954 hasConcept C71924100 @default.
• W4384697954 hasConcept C8868529 @default.

• next