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- W4384703771 abstract "Background: Megaloblastic anemia encompasses a heterogenous group of anemias characterized by the presence in the bone marrow of large blood cell precursors called Megaloblasts. Megaloblastic anemia is most often due to hypovitaminosis, specically vitamin B12 (Cobalamin) and folate, which are necessary for the synthesis of DNA. Overt neurological manifestations of megaloblastic anemia are well documented but there is paucity of data on the existence of subclinical neurological manifestations in Megaloblastic anemia. Hence, we have undertaken this study, to assess the clinical prole of the patients with the megaloblastic anemia. Methods: Present study was prospective in nature conducted among 100 megaloblastic anemia patients. All patients fullling inclusion criteria and exclusion criteria were taken up for the study. Study was carried out over a period of 1.5 years. Results: Majority of the patients was in the age group of 31-40 years and most of them were male. Anisopoikilocytosis (86%) was the commonest peripheral blood smear ndings amongst study population. Out of 100, 29 patients had axonal neuropathy, 10 patients had demyelinating neuropathy and 1 had axonal as well as demyelinating neuropathy. Conclusion: Besides bedside neurological examination, further Nerve conduction study examination is helpful for the evaluation of neuropathies and studies can be considered to monitor the progression of disease and understanding of the varied spectrum of neurological manifestations of megaloblastic anemia" @default.
- W4384703771 created "2023-07-20" @default.
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- W4384703771 date "2023-06-01" @default.
- W4384703771 modified "2023-09-26" @default.
- W4384703771 title "STUDY OF CLINICAL PROFILE OF MEGALOBLASTIC ANEMIA." @default.
- W4384703771 doi "https://doi.org/10.36106/ijsr/2814604" @default.
- W4384703771 hasPublicationYear "2023" @default.
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