Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384788165> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W4384788165 endingPage "486" @default.
- W4384788165 startingPage "481" @default.
- W4384788165 abstract "Mechanistic models are an important tool as they allow storage of process knowledge and enable model-based techniques to plan, monitor, and control biological processes. Fundamental to these operations are models that can accurately describe their in vivo counterpart. Therefore, good modelling practices have been described including different analysis steps to ensure and maintain identifiability of model parameters during model calibration and the model life cycle (Daume et al., 2020). Here, a workflow to analyze, adapt and apply a mechanistic model for experimental planning is suggested and its application demonstrated with a set of fed-batch refolding experiments conducted in the controlled environment of a stirred tank reactor. The model is based on the folding kinetics of a recombinant protein solubilized from aggregated proteins accumulated inside bacterial inclusion bodies. Along the adaptation cycle the model is analyzed for unique identifiability of model parameters both from simulations and noisy measurements." @default.
- W4384788165 created "2023-07-20" @default.
- W4384788165 creator A5055332747 @default.
- W4384788165 creator A5055979361 @default.
- W4384788165 creator A5067132720 @default.
- W4384788165 date "2023-01-01" @default.
- W4384788165 modified "2023-09-27" @default.
- W4384788165 title "Workflow for adaptation, analysis and application of mechanistic models for experimental planning of protein refolding processes" @default.
- W4384788165 cites W1998523300 @default.
- W4384788165 cites W2035128850 @default.
- W4384788165 cites W2036407535 @default.
- W4384788165 cites W2772838281 @default.
- W4384788165 cites W2810205462 @default.
- W4384788165 cites W2963917915 @default.
- W4384788165 cites W2990581410 @default.
- W4384788165 cites W3093847671 @default.
- W4384788165 cites W3132404023 @default.
- W4384788165 doi "https://doi.org/10.1016/b978-0-443-15274-0.50077-9" @default.
- W4384788165 hasPublicationYear "2023" @default.
- W4384788165 type Work @default.
- W4384788165 citedByCount "0" @default.
- W4384788165 crossrefType "book-chapter" @default.
- W4384788165 hasAuthorship W4384788165A5055332747 @default.
- W4384788165 hasAuthorship W4384788165A5055979361 @default.
- W4384788165 hasAuthorship W4384788165A5067132720 @default.
- W4384788165 hasConcept C111919701 @default.
- W4384788165 hasConcept C119857082 @default.
- W4384788165 hasConcept C122770356 @default.
- W4384788165 hasConcept C127413603 @default.
- W4384788165 hasConcept C139807058 @default.
- W4384788165 hasConcept C169760540 @default.
- W4384788165 hasConcept C177212765 @default.
- W4384788165 hasConcept C183696295 @default.
- W4384788165 hasConcept C186060115 @default.
- W4384788165 hasConcept C41008148 @default.
- W4384788165 hasConcept C77088390 @default.
- W4384788165 hasConcept C86803240 @default.
- W4384788165 hasConcept C98045186 @default.
- W4384788165 hasConceptScore W4384788165C111919701 @default.
- W4384788165 hasConceptScore W4384788165C119857082 @default.
- W4384788165 hasConceptScore W4384788165C122770356 @default.
- W4384788165 hasConceptScore W4384788165C127413603 @default.
- W4384788165 hasConceptScore W4384788165C139807058 @default.
- W4384788165 hasConceptScore W4384788165C169760540 @default.
- W4384788165 hasConceptScore W4384788165C177212765 @default.
- W4384788165 hasConceptScore W4384788165C183696295 @default.
- W4384788165 hasConceptScore W4384788165C186060115 @default.
- W4384788165 hasConceptScore W4384788165C41008148 @default.
- W4384788165 hasConceptScore W4384788165C77088390 @default.
- W4384788165 hasConceptScore W4384788165C86803240 @default.
- W4384788165 hasConceptScore W4384788165C98045186 @default.
- W4384788165 hasFunder F4320318434 @default.
- W4384788165 hasFunder F4320323031 @default.
- W4384788165 hasFunder F4320327593 @default.
- W4384788165 hasLocation W43847881651 @default.
- W4384788165 hasOpenAccess W4384788165 @default.
- W4384788165 hasPrimaryLocation W43847881651 @default.
- W4384788165 hasRelatedWork W1571518467 @default.
- W4384788165 hasRelatedWork W2081035100 @default.
- W4384788165 hasRelatedWork W2081587371 @default.
- W4384788165 hasRelatedWork W2162148600 @default.
- W4384788165 hasRelatedWork W2395457915 @default.
- W4384788165 hasRelatedWork W2408864606 @default.
- W4384788165 hasRelatedWork W3206324740 @default.
- W4384788165 hasRelatedWork W64186914 @default.
- W4384788165 hasRelatedWork W86388759 @default.
- W4384788165 hasRelatedWork W87991986 @default.
- W4384788165 isParatext "false" @default.
- W4384788165 isRetracted "false" @default.
- W4384788165 workType "book-chapter" @default.