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- W4384807038 abstract "Purpose To assess the long-term outcomes of corneal collagen cross linking according to the Dresden protocol (S-CXL) in progressive pediatric keratoconus (KC). Design retrospective, single-centre non-comparative interventional study. Methods patients below 18 years of age who underwent to S-CXL from June 2007 to January 2011 in Humanitas Clinical and Research Center, Rozzano, (MI), Italy and completed at least 10 years of follow-up were included. Corrected distance visual acuity (CDVA), refraction, tomography with Pentacam (OCULUS, Wetzlar, Germany) were evaluated at baseline and 10+ years after S-CXL. Definition of re-progression was 2/3 criteria of the following: progression above 95% Confidence Interval for post-CXL population of “A” or “B” values or decrease of minimal thickness “C” evaluated with the ABCD display. Results Thirty-eight eyes of 24 patients fulfilled inclusion criteria. At a mean of 11.6 years post-op (maximum 14 years), CDVA improved significantly (from 0.703 ± 0.33 decimal fraction to 0.887 ± 0.2, p < 0.001). Similarly, A value significantly improved from 2.550 ± 1.7 to 1.627 ± 1.68 (p = 0.019). Thirteen eyes (34%) showed significant post-operative progression of two out of three among A, B and C parameters. Of these, only 3 eyes (7.9%) of 3 patients showed a statistically significant change of A value . Conclusions S-CXL confirmed to be a safe treatment for progressive KC in paediatric patients with an anterior curvature progression rate of up to 7.9% at 10+ years of follow-up." @default.
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- W4384807038 date "2023-11-01" @default.
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- W4384807038 title "Corneal Collagen Cross Linking for Progressive Keratoconus in Paediatric Patients: up to 14 years of follow up." @default.
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- W4384807038 doi "https://doi.org/10.1016/j.ajo.2023.07.017" @default.
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