Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384818295> ?p ?o ?g. }
- W4384818295 endingPage "110838" @default.
- W4384818295 startingPage "110838" @default.
- W4384818295 abstract "This study aimed to investigate the role of the lactate dehydrogenase (LDH) in the development of end-stage renal disease (ESRD) and the cardiovascular mortality in individuals with diabetic kidney disease (DKD).Two cohorts were recruited in this study. We explored the correlation between LDH and renal injury in individuals with DKD in using a Cohort 1. Additionally, we validated this correlation in the NHANES database and further investigated its association with the risk of cardiovascular mortality in Cohort 2 which also comprised individuals with DKD.In cohort 1, multivariate Cox regression analysis demonstrated that individuals in DKD with higher LDH were independently associated with an increased risk of ESRD compared to those with lower LDH (HR = 2.11; 95 % CI, 1.07-4.16). In cohort 2, linear regression models showed that LDH affects the level of albumin-creatinine ratio (ACR) (β = 2.95, P = 0.001). Additionally, multivariate Cox regression analysis results showed that an increase in LDH per 1-standard deviation (SD) was associated with a 27 % increased risk of cardiovascular mortality (HR = 1.27; 95 % CI, 1.09-1.48).LDH levels are associated with renal injury and progression to ESRD, as well as being an independent risk factor for cardiovascular in individuals with DKD." @default.
- W4384818295 created "2023-07-21" @default.
- W4384818295 creator A5006678012 @default.
- W4384818295 creator A5024410659 @default.
- W4384818295 creator A5058668034 @default.
- W4384818295 creator A5064947784 @default.
- W4384818295 creator A5066071162 @default.
- W4384818295 creator A5073024272 @default.
- W4384818295 creator A5080611527 @default.
- W4384818295 creator A5080680986 @default.
- W4384818295 creator A5089065455 @default.
- W4384818295 date "2023-09-01" @default.
- W4384818295 modified "2023-10-14" @default.
- W4384818295 title "Associations of lactate dehydrogenase with risk of renal outcomes and cardiovascular mortality in individuals with diabetic kidney disease" @default.
- W4384818295 cites W1616394907 @default.
- W4384818295 cites W1971285535 @default.
- W4384818295 cites W1998777863 @default.
- W4384818295 cites W2017489165 @default.
- W4384818295 cites W2049352004 @default.
- W4384818295 cites W2062420270 @default.
- W4384818295 cites W2063880582 @default.
- W4384818295 cites W2119035208 @default.
- W4384818295 cites W2136490577 @default.
- W4384818295 cites W2157370605 @default.
- W4384818295 cites W2193267731 @default.
- W4384818295 cites W2281848173 @default.
- W4384818295 cites W2512638651 @default.
- W4384818295 cites W2516337081 @default.
- W4384818295 cites W2536321822 @default.
- W4384818295 cites W2790190820 @default.
- W4384818295 cites W2807942571 @default.
- W4384818295 cites W2810788601 @default.
- W4384818295 cites W2887185538 @default.
- W4384818295 cites W2947550210 @default.
- W4384818295 cites W2982216374 @default.
- W4384818295 cites W3043821164 @default.
- W4384818295 cites W3080945733 @default.
- W4384818295 cites W3107923716 @default.
- W4384818295 cites W3117558629 @default.
- W4384818295 cites W3127304963 @default.
- W4384818295 cites W3176005729 @default.
- W4384818295 cites W3200479416 @default.
- W4384818295 cites W3214349254 @default.
- W4384818295 cites W4205143046 @default.
- W4384818295 cites W4214525262 @default.
- W4384818295 cites W4236121725 @default.
- W4384818295 cites W4303446545 @default.
- W4384818295 cites W4307898883 @default.
- W4384818295 cites W4308158468 @default.
- W4384818295 cites W4308620468 @default.
- W4384818295 cites W4311852495 @default.
- W4384818295 doi "https://doi.org/10.1016/j.diabres.2023.110838" @default.
- W4384818295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37478980" @default.
- W4384818295 hasPublicationYear "2023" @default.
- W4384818295 type Work @default.
- W4384818295 citedByCount "0" @default.
- W4384818295 crossrefType "journal-article" @default.
- W4384818295 hasAuthorship W4384818295A5006678012 @default.
- W4384818295 hasAuthorship W4384818295A5024410659 @default.
- W4384818295 hasAuthorship W4384818295A5058668034 @default.
- W4384818295 hasAuthorship W4384818295A5064947784 @default.
- W4384818295 hasAuthorship W4384818295A5066071162 @default.
- W4384818295 hasAuthorship W4384818295A5073024272 @default.
- W4384818295 hasAuthorship W4384818295A5080611527 @default.
- W4384818295 hasAuthorship W4384818295A5080680986 @default.
- W4384818295 hasAuthorship W4384818295A5089065455 @default.
- W4384818295 hasConcept C126322002 @default.
- W4384818295 hasConcept C134018914 @default.
- W4384818295 hasConcept C159641895 @default.
- W4384818295 hasConcept C181199279 @default.
- W4384818295 hasConcept C201903717 @default.
- W4384818295 hasConcept C2777318727 @default.
- W4384818295 hasConcept C2778653478 @default.
- W4384818295 hasConcept C2779134260 @default.
- W4384818295 hasConcept C2780306776 @default.
- W4384818295 hasConcept C3019040382 @default.
- W4384818295 hasConcept C50382708 @default.
- W4384818295 hasConcept C55493867 @default.
- W4384818295 hasConcept C555293320 @default.
- W4384818295 hasConcept C71924100 @default.
- W4384818295 hasConcept C72563966 @default.
- W4384818295 hasConcept C86803240 @default.
- W4384818295 hasConceptScore W4384818295C126322002 @default.
- W4384818295 hasConceptScore W4384818295C134018914 @default.
- W4384818295 hasConceptScore W4384818295C159641895 @default.
- W4384818295 hasConceptScore W4384818295C181199279 @default.
- W4384818295 hasConceptScore W4384818295C201903717 @default.
- W4384818295 hasConceptScore W4384818295C2777318727 @default.
- W4384818295 hasConceptScore W4384818295C2778653478 @default.
- W4384818295 hasConceptScore W4384818295C2779134260 @default.
- W4384818295 hasConceptScore W4384818295C2780306776 @default.
- W4384818295 hasConceptScore W4384818295C3019040382 @default.
- W4384818295 hasConceptScore W4384818295C50382708 @default.
- W4384818295 hasConceptScore W4384818295C55493867 @default.
- W4384818295 hasConceptScore W4384818295C555293320 @default.
- W4384818295 hasConceptScore W4384818295C71924100 @default.
- W4384818295 hasConceptScore W4384818295C72563966 @default.
- W4384818295 hasConceptScore W4384818295C86803240 @default.