FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384820596> ?p ?o ?g. }

• W4384820596 abstract "Abstract Background The importance of COVID-19 vaccination for patients on immunosuppressive (IS) medication has increased due to the high risk of severe disease or mortality. Different vaccines have varying efficacy rates against symptomatic COVID-19, ranging from 46.8% to 95%. The objective of this study was to examine the differences in anti-Spike IgG, anti-Spike IgA, and neutralizing antibody (NAb) activity between the inactive CoronaVac vaccine and the mRNA-based BNT162b2 vaccine in IS patients. Method A total of 441 volunteers, including 104 IS patients, 263 healthy controls (HC), who received two doses of CoronaVac or BNT162b2, and 74 unvaccinated patients with a history of SARS-CoV-2 infection, were included in the study. Anti-spike IgG, IgA, and NAb activity were investigated. Results Immunogenicity with BNT162b2 was higher than with CoronaVac, but in IS groups, it was lower than HC (CoronaVac-IS: 79.3%, CoronaVac-HC: 96.5%, p < 0.001; BNT162b2-IS: 91.3%, BNT162b2-HC: 100%, p = 0.005). With CoronaVac, anti-Spike IgG levels were significantly lower than BNT162b2 (CoronaVac-IS: 234.5AU/mL, CoronaVac-HC: 457.85AU/mL; BNT162b2-IS: 5311.2AU/mL, BNT162b2-HC: 8842.8AU/mL). NAb activity in the BNT162b2 group was significantly higher. NAb and anti-Spike IgG levels were found to be correlated. Among the IS group, a significantly lower response to the vaccines was observed when using rituximab. IgA levels were found to be lower with CoronaVac. Conclusions Although immunogenicity was lower in IS patients, an acceptable response was obtained with both vaccines, and significantly higher anti-Spike IgG, anti-Spike IgA, and NAb activity levels were obtained with BNT162b2." @default.
• W4384820596 created "2023-07-21" @default.
• W4384820596 creator A5017823161 @default.
• W4384820596 creator A5020263758 @default.
• W4384820596 creator A5021353564 @default.
• W4384820596 creator A5038401466 @default.
• W4384820596 creator A5045620537 @default.
• W4384820596 creator A5046504541 @default.
• W4384820596 creator A5055654325 @default.
• W4384820596 creator A5067202925 @default.
• W4384820596 creator A5081372176 @default.
• W4384820596 creator A5082138538 @default.
• W4384820596 creator A5092500255 @default.
• W4384820596 date "2023-07-19" @default.
• W4384820596 modified "2023-10-06" @default.
• W4384820596 title "Comparison of anti-spike IgG, anti-spike IgA levels and neutralizing antibody activity induced by CoronaVac and BNT162b2 vaccines in patients with inflammatory rheumatic diseases receiving immunosuppressive therapy" @default.
• W4384820596 cites W3013985547 @default.
• W4384820596 cites W3018013720 @default.
• W4384820596 cites W3034680516 @default.
• W4384820596 cites W3046309975 @default.
• W4384820596 cites W3088489318 @default.
• W4384820596 cites W3092705824 @default.
• W4384820596 cites W3093554406 @default.
• W4384820596 cites W3097960438 @default.
• W4384820596 cites W3112389805 @default.
• W4384820596 cites W3112956657 @default.
• W4384820596 cites W3132228753 @default.
• W4384820596 cites W3133327867 @default.
• W4384820596 cites W3158032196 @default.
• W4384820596 cites W3158270843 @default.
• W4384820596 cites W3163785571 @default.
• W4384820596 cites W3164014942 @default.
• W4384820596 cites W3164069651 @default.
• W4384820596 cites W3172019122 @default.
• W4384820596 cites W3186114398 @default.
• W4384820596 cites W3195688082 @default.
• W4384820596 cites W3197081215 @default.
• W4384820596 cites W3215144161 @default.
• W4384820596 cites W4224942813 @default.
• W4384820596 cites W4225489846 @default.
• W4384820596 cites W4225854071 @default.
• W4384820596 cites W4226321964 @default.
• W4384820596 doi "https://doi.org/10.1186/s41927-023-00342-x" @default.
• W4384820596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37468956" @default.
• W4384820596 hasPublicationYear "2023" @default.
• W4384820596 type Work @default.
• W4384820596 citedByCount "0" @default.
• W4384820596 crossrefType "journal-article" @default.
• W4384820596 hasAuthorship W4384820596A5017823161 @default.
• W4384820596 hasAuthorship W4384820596A5020263758 @default.
• W4384820596 hasAuthorship W4384820596A5021353564 @default.
• W4384820596 hasAuthorship W4384820596A5038401466 @default.
• W4384820596 hasAuthorship W4384820596A5045620537 @default.
• W4384820596 hasAuthorship W4384820596A5046504541 @default.
• W4384820596 hasAuthorship W4384820596A5055654325 @default.
• W4384820596 hasAuthorship W4384820596A5067202925 @default.
• W4384820596 hasAuthorship W4384820596A5081372176 @default.
• W4384820596 hasAuthorship W4384820596A5082138538 @default.
• W4384820596 hasAuthorship W4384820596A5092500255 @default.
• W4384820596 hasBestOaLocation W43848205961 @default.
• W4384820596 hasConcept C126322002 @default.
• W4384820596 hasConcept C159654299 @default.
• W4384820596 hasConcept C203014093 @default.
• W4384820596 hasConcept C22070199 @default.
• W4384820596 hasConcept C2779134260 @default.
• W4384820596 hasConcept C2780868878 @default.
• W4384820596 hasConcept C2909509916 @default.
• W4384820596 hasConcept C3007834351 @default.
• W4384820596 hasConcept C3008058167 @default.
• W4384820596 hasConcept C524204448 @default.
• W4384820596 hasConcept C71924100 @default.
• W4384820596 hasConceptScore W4384820596C126322002 @default.
• W4384820596 hasConceptScore W4384820596C159654299 @default.
• W4384820596 hasConceptScore W4384820596C203014093 @default.
• W4384820596 hasConceptScore W4384820596C22070199 @default.
• W4384820596 hasConceptScore W4384820596C2779134260 @default.
• W4384820596 hasConceptScore W4384820596C2780868878 @default.
• W4384820596 hasConceptScore W4384820596C2909509916 @default.
• W4384820596 hasConceptScore W4384820596C3007834351 @default.
• W4384820596 hasConceptScore W4384820596C3008058167 @default.
• W4384820596 hasConceptScore W4384820596C524204448 @default.
• W4384820596 hasConceptScore W4384820596C71924100 @default.
• W4384820596 hasFunder F4320329122 @default.
• W4384820596 hasIssue "1" @default.
• W4384820596 hasLocation W43848205961 @default.
• W4384820596 hasLocation W43848205962 @default.
• W4384820596 hasOpenAccess W4384820596 @default.
• W4384820596 hasPrimaryLocation W43848205961 @default.
• W4384820596 hasRelatedWork W2029074520 @default.
• W4384820596 hasRelatedWork W2145317919 @default.
• W4384820596 hasRelatedWork W2411114470 @default.
• W4384820596 hasRelatedWork W2466910529 @default.
• W4384820596 hasRelatedWork W2751942428 @default.
• W4384820596 hasRelatedWork W3036305013 @default.
• W4384820596 hasRelatedWork W3045746510 @default.
• W4384820596 hasRelatedWork W4313274444 @default.
• W4384820596 hasRelatedWork W4360788232 @default.
• W4384820596 hasRelatedWork W4365148422 @default.
• W4384820596 hasVolume "7" @default.
• W4384820596 isParatext "false" @default.

• next