FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384922401> ?p ?o ?g. }

• W4384922401 endingPage "570" @default.
• W4384922401 startingPage "559" @default.
• W4384922401 abstract "Two arene ruthenium(II) complexes [η6-(C6H6)Ru(pprip)Cl]PF6 (Ru1; pprip = 2-(3-phenyl-1H-pyrazol-4-yl)-imidazolo[4,5-f][1,10]phenanthroline) and [η6-(C6H6)Ru(H2iiP)Cl]PF6 (Ru2; H2iiP = 2-(indole-3-yl)-imidazolo[4,5-f][1,10]phenanthroline) have been synthesized and characterized in this work. Binding properties of Ru1 and Ru2 with the triplex RNA poly(U)•poly(A)*poly(U) were investigated by spectrophotometry and spectrofluorometry as well as viscosimetry. Analysis of spectroscopic titrations and viscosity measurements show that the two complexes bind with the triplex through intercalation, while the binding affinity for Ru2 toward the triplex is stronger than that for Ru1. Melting experiments indicate that the stabilizing effects of Ru1 and Ru2 toward the triplex differ from each other. Under the conditions used herein, Ru1 only stabilizes the Hoogsteen base-paired strand (third strand) without affecting stabilization of the Watson-Crick base-paired strand (the template duplex) of the triplex, while Ru2 stabilizes both the template duplex and the third strand. Although the two complexes prefer to stabilizing the third strand rather than the template duplex, the third-strand stabilization effect of Ru2 is stronger than that of Ru1. The obtained results of this work reveal that the planarity of the intercalative ligands plays an important role in the triplex stabilization by arene Ru(II) complexes." @default.
• W4384922401 created "2023-07-22" @default.
• W4384922401 creator A5016898882 @default.
• W4384922401 creator A5032926098 @default.
• W4384922401 creator A5049234288 @default.
• W4384922401 creator A5064597564 @default.
• W4384922401 date "2023-07-21" @default.
• W4384922401 modified "2023-10-01" @default.
• W4384922401 title "Interactions of arene ruthenium(II) complexes [η6-(C6H6)Ru(pprip)Cl]+ and [η6-(C6H6)Ru(H2iiP)Cl]+ with RNA triplex poly(U)•poly(A)*poly(U)" @default.
• W4384922401 cites W1784676900 @default.
• W4384922401 cites W1975402304 @default.
• W4384922401 cites W1978438294 @default.
• W4384922401 cites W1980460953 @default.
• W4384922401 cites W1989998876 @default.
• W4384922401 cites W2002338086 @default.
• W4384922401 cites W2017346763 @default.
• W4384922401 cites W2017680066 @default.
• W4384922401 cites W2019562359 @default.
• W4384922401 cites W2029852148 @default.
• W4384922401 cites W2031077432 @default.
• W4384922401 cites W2033351654 @default.
• W4384922401 cites W2038822441 @default.
• W4384922401 cites W2039007599 @default.
• W4384922401 cites W2039395857 @default.
• W4384922401 cites W2040184556 @default.
• W4384922401 cites W2042419740 @default.
• W4384922401 cites W2050077837 @default.
• W4384922401 cites W2057972907 @default.
• W4384922401 cites W2061856395 @default.
• W4384922401 cites W2063100012 @default.
• W4384922401 cites W2077567454 @default.
• W4384922401 cites W2081446791 @default.
• W4384922401 cites W2082845860 @default.
• W4384922401 cites W2088695864 @default.
• W4384922401 cites W2090034645 @default.
• W4384922401 cites W2092313231 @default.
• W4384922401 cites W2096608756 @default.
• W4384922401 cites W2128294421 @default.
• W4384922401 cites W2163237642 @default.
• W4384922401 cites W2169053981 @default.
• W4384922401 cites W2169472147 @default.
• W4384922401 cites W2210369932 @default.
• W4384922401 cites W2313993185 @default.
• W4384922401 cites W2317870003 @default.
• W4384922401 cites W2322716488 @default.
• W4384922401 cites W2326881334 @default.
• W4384922401 cites W2331531468 @default.
• W4384922401 cites W2419207612 @default.
• W4384922401 cites W2569386536 @default.
• W4384922401 cites W2762800385 @default.
• W4384922401 cites W2943343599 @default.
• W4384922401 cites W2949248773 @default.
• W4384922401 cites W2960838284 @default.
• W4384922401 cites W3021815292 @default.
• W4384922401 cites W3090252070 @default.
• W4384922401 cites W3118649288 @default.
• W4384922401 cites W4223499075 @default.
• W4384922401 cites W4247136962 @default.
• W4384922401 cites W4289547262 @default.
• W4384922401 cites W4289767280 @default.
• W4384922401 cites W4293211553 @default.
• W4384922401 cites W573591720 @default.
• W4384922401 doi "https://doi.org/10.1007/s00775-023-02008-y" @default.
• W4384922401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37477757" @default.
• W4384922401 hasPublicationYear "2023" @default.
• W4384922401 type Work @default.
• W4384922401 citedByCount "1" @default.
• W4384922401 countsByYear W43849224012023 @default.
• W4384922401 crossrefType "journal-article" @default.
• W4384922401 hasAuthorship W4384922401A5016898882 @default.
• W4384922401 hasAuthorship W4384922401A5032926098 @default.
• W4384922401 hasAuthorship W4384922401A5049234288 @default.
• W4384922401 hasAuthorship W4384922401A5064597564 @default.
• W4384922401 hasBestOaLocation W43849224011 @default.
• W4384922401 hasConcept C137824038 @default.
• W4384922401 hasConcept C161790260 @default.
• W4384922401 hasConcept C178790620 @default.
• W4384922401 hasConcept C179104552 @default.
• W4384922401 hasConcept C184866935 @default.
• W4384922401 hasConcept C185581394 @default.
• W4384922401 hasConcept C185592680 @default.
• W4384922401 hasConcept C2777660389 @default.
• W4384922401 hasConcept C552990157 @default.
• W4384922401 hasConcept C55493867 @default.
• W4384922401 hasConcept C555196967 @default.
• W4384922401 hasConcept C71240020 @default.
• W4384922401 hasConcept C8010536 @default.
• W4384922401 hasConcept C99611785 @default.
• W4384922401 hasConceptScore W4384922401C137824038 @default.
• W4384922401 hasConceptScore W4384922401C161790260 @default.
• W4384922401 hasConceptScore W4384922401C178790620 @default.
• W4384922401 hasConceptScore W4384922401C179104552 @default.
• W4384922401 hasConceptScore W4384922401C184866935 @default.
• W4384922401 hasConceptScore W4384922401C185581394 @default.
• W4384922401 hasConceptScore W4384922401C185592680 @default.
• W4384922401 hasConceptScore W4384922401C2777660389 @default.
• W4384922401 hasConceptScore W4384922401C552990157 @default.
• W4384922401 hasConceptScore W4384922401C55493867 @default.

• next