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- W4384923139 abstract "Background Pressure-controlled face mask ventilation (PC-FMV) with positive end-expiratory pressure (PEEP) after apnoea following induction of general anaesthesia prolongs safe apnoea time and reduces atelectasis formation. However, depending on the set inspiratory pressure, a delayed confirmation of a patent airway might occur. We hypothesised that by lowering the peak inspiratory pressure (PIP) when using PC-FMV with PEEP, confirmation of a patent airway would not be delayed as studied by the first return of CO2, compared with manual face mask ventilation (Manual FMV). Methods This was a single-centre, randomised controlled non-inferiority trial. Seventy adult patients scheduled for elective day-case surgery under general anaesthesia with body mass index between 18.5 and 29.9 kg m−2, American Society of Anesthesiologists (ASA) classes I–III, and without anticipated difficult FMV, were included. Before the start of pre-oxygenation and induction of general anaesthesia, participants were randomly allocated to receive ventilation with either PC-FMV with PEEP, at a PIP of 11 and a PEEP of 6 cmH2O or Manual FMV, with the adjustable pressure-limiting valve set at 11 cmH2O. The primary outcome variable was the number of ventilatory attempts needed until confirmation of a patent airway, defined as the return of at least 1.3 kPa CO2. Results The return of ≥1.3 kPa CO2 on the capnography curve was observed after mean ± SD, 3.6 ± 4.2 and 2.5 ± 1.9 ventilatory attempts/breaths with PC-FMV with PEEP and Manual FMV, respectively. The difference in means (1.1 ventilatory attempts/breaths) had a 99% CI of −1.0 to 3.1, within the accepted upper margin of four breaths for non-inferiority. Conclusion Following induction of general anaesthesia, PC-FMV with PEEP was used without delaying a patent airway as confirmed with capnography, if moderate pressures were used." @default.
- W4384923139 created "2023-07-22" @default.
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- W4384923139 date "2023-07-21" @default.
- W4384923139 modified "2023-09-27" @default.
- W4384923139 title "Pressure‐controlled versus manual facemask ventilation for anaesthetic induction in adults: A randomised controlled non‐inferiority trial" @default.
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- W4384923139 doi "https://doi.org/10.1111/aas.14308" @default.
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