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- W4384933477 abstract "Background ：Allergic diseases are increasing globally, including in China. This poses challenges to public health. Our study aimed to investigate allergens in children from Sichuan Province and their impact on dermatitis, rhinitis, and asthma. Methods ：This retrospective study analyzed the medical records of 3204 pediatric patients aged 0-9 years at XXX. Serum samples were collected and tested using a microfluidic-based enzyme-linked immunoassay. The analysis focused on detecting allergen-specific immunoglobulin E for 20 food allergens and aeroallergens. Results ：In this study, the proportions of children allergic to at least one allergen varied across different age groups. For children aged <1 year, 1-3 years, and 3-9 years, the proportions were 40.40%, 68.54%, and 37.66%, respectively. Boys showed a higher susceptibility to atopic allergies compared to girls (P<0.001). The prevalence of both food allergens and aeroallergens was high among the study participants. Among the food allergens, egg white (52.25%) and cow’s milk (39.33%) were the most prevalent, while Dermatophagoides pteronyssinus (41.88%) and Dermatophagoides farina (35.23%) were the most commonly observed aeroallergens. The intensity scores of food allergens decreased with increasing age, while the intensity scores of aeroallergens exhibited the opposite trend. The population attributable risk (PAR) of atopy for dermatitis was lower in the 3-9 years age group (40.10%) compared to younger children (<1 year: 63.40%; 1-3 years: 65.10%). Conclusions ：The prevalence of atopic allergies varies with age and gender. Additionally, the intensity of food allergens and aeroallergens shows an age-related pattern. The proportion of dermatitis, rhinitis, and asthma that can be attributed to atopy remains consistently high across all age groups. However, there are differences in the population attributable risk (PAR) of atopy for dermatitis and asthma among different age groups." @default.
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- W4384933477 date "2023-07-20" @default.
- W4384933477 modified "2023-10-11" @default.
- W4384933477 title "Allergy Burden in Sichuan, China: Investigating Prevalence, Patterns, and Population Attributable Risks among Children" @default.
- W4384933477 doi "https://doi.org/10.22541/au.168987244.48299962/v1" @default.
- W4384933477 hasPublicationYear "2023" @default.
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