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- W4385012107 abstract "The concentration of Nτ-methylhistidine in plasma provides an index of skeletal muscle protein breakdown. This study aimed to establish a quantitative method for measuring the concentrations of Nτ-methylhistidine and its isomer Nπ-methylhistidine in chicken plasma, using liquid chromatography–tandem mass spectrometry with stable isotope dilution analysis. The acceptable linear ranges of detection were 1.56–50.00 μmol/L for Nτ-methylhistidine and 0.78–25.00 μmol/L for Nπ-methylhistidine. The proposed method detected changes in the plasma levels of Nτ-methylhistidine and Nπ-methylhistidine in response to fasting and re-feeding. These results suggest that the method developed in this study can be used for the simultaneous measurement of Nτ-methylhistidine and Nπ-methylhistidine in chicken plasma." @default.
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- W4385012107 date "2023-01-01" @default.
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- W4385012107 title "Quantification of N<sup>τ</sup> -Methylhistidine and N<sup>π</sup>-Methylhistidine in Chicken Plasma by Liquid Chromatography–Tandem Mass Spectrometry" @default.
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- W4385012107 doi "https://doi.org/10.2141/jpsa.2023017" @default.
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