FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385064084> ?p ?o ?g. }

• W4385064084 abstract "Abstract Background Inflammation is considered to be one of the driving factors of cancer, and chronic inflammation plays a crucial role in tumor growth and metastasis. The aim of this study was to examine the predictive value of preoperative inflammatory biomarkers for overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC), including preoperative neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and aspartate aminotransferase-to-lymphocyte ratio (ALR), a novel inflammatory biomarker. Method This study included 198 patients with mRCC from a single center from 2006 to 2022. The optimal cut-off levels for the three biomarkers were derived using the receiver operating characteristic curve (ROC). Cox univariate and multivariate analyses were used to assess independent prognostic inflammatory biomarkers. Finally, independent prognostic inflammatory biomarkers were incorporated into the prognostic model to establish a nomogram to predict the postoperative survival of patients with mRCC. Result The area under the ROC curve for NLR, LMR, and ALR, respectively, is 0.71 (CI: 0.635–0.784), 0.68 (CI: 0.604–0.755), and 0.75 (CI: 0.680–0.819). The optimal LMR, NLR, and ALR cut-off levels as evaluated by the ROC curve were 3.836, 3.106, and 68.056, respectively. Patients with NLR and ALR higher than the cut-off level and LMR lower than the cut-off level had a significant relationship with OS. Multivariate analysis revealed that tumor necrosis, lower LMR, and higher ALR were independent risk factors for OS. In addition, a nomogram that includes independent prognostic inflammatory biomarkers can accurately predict the OS in patients with mRCC. Conclusion ALR and LMR are independent risk factors for the prognosis of individuals with mRCC. By monitoring ALR and LMR postoperatively, the prognosis of patients with mRCC can be better evaluated." @default.
• W4385064084 created "2023-07-23" @default.
• W4385064084 creator A5004231602 @default.
• W4385064084 creator A5036775123 @default.
• W4385064084 creator A5039303569 @default.
• W4385064084 creator A5049852965 @default.
• W4385064084 creator A5075097725 @default.
• W4385064084 date "2023-07-21" @default.
• W4385064084 modified "2023-10-18" @default.
• W4385064084 title "Prognostic value and model construction of preoperative inflammatory markers in patients with metastatic renal cell carcinoma" @default.
• W4385064084 cites W1942447546 @default.
• W4385064084 cites W1993013170 @default.
• W4385064084 cites W1996472967 @default.
• W4385064084 cites W2010914546 @default.
• W4385064084 cites W2044217594 @default.
• W4385064084 cites W2051613372 @default.
• W4385064084 cites W2063903287 @default.
• W4385064084 cites W2087817050 @default.
• W4385064084 cites W2088741578 @default.
• W4385064084 cites W2106637705 @default.
• W4385064084 cites W2107254151 @default.
• W4385064084 cites W2121692731 @default.
• W4385064084 cites W2127331530 @default.
• W4385064084 cites W2133986993 @default.
• W4385064084 cites W2171431790 @default.
• W4385064084 cites W2212270379 @default.
• W4385064084 cites W2375601132 @default.
• W4385064084 cites W2470477092 @default.
• W4385064084 cites W2507163473 @default.
• W4385064084 cites W2589234404 @default.
• W4385064084 cites W2595336303 @default.
• W4385064084 cites W2612200829 @default.
• W4385064084 cites W2686511444 @default.
• W4385064084 cites W2791431060 @default.
• W4385064084 cites W2946896984 @default.
• W4385064084 cites W2964902343 @default.
• W4385064084 cites W296967391 @default.
• W4385064084 cites W2970452995 @default.
• W4385064084 cites W2991268660 @default.
• W4385064084 cites W3012194080 @default.
• W4385064084 cites W3035358954 @default.
• W4385064084 cites W3037945904 @default.
• W4385064084 cites W3083259637 @default.
• W4385064084 cites W3087318717 @default.
• W4385064084 cites W3089235298 @default.
• W4385064084 cites W3109353944 @default.
• W4385064084 cites W3110046119 @default.
• W4385064084 cites W3159650591 @default.
• W4385064084 doi "https://doi.org/10.1186/s12957-023-03110-w" @default.
• W4385064084 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37480143" @default.
• W4385064084 hasPublicationYear "2023" @default.
• W4385064084 type Work @default.
• W4385064084 citedByCount "0" @default.
• W4385064084 crossrefType "journal-article" @default.
• W4385064084 hasAuthorship W4385064084A5004231602 @default.
• W4385064084 hasAuthorship W4385064084A5036775123 @default.
• W4385064084 hasAuthorship W4385064084A5039303569 @default.
• W4385064084 hasAuthorship W4385064084A5049852965 @default.
• W4385064084 hasAuthorship W4385064084A5075097725 @default.
• W4385064084 hasBestOaLocation W43850640841 @default.
• W4385064084 hasConcept C126322002 @default.
• W4385064084 hasConcept C142724271 @default.
• W4385064084 hasConcept C143998085 @default.
• W4385064084 hasConcept C144301174 @default.
• W4385064084 hasConcept C185592680 @default.
• W4385064084 hasConcept C2776914184 @default.
• W4385064084 hasConcept C2777472916 @default.
• W4385064084 hasConcept C2777761686 @default.
• W4385064084 hasConcept C2778963024 @default.
• W4385064084 hasConcept C2780140570 @default.
• W4385064084 hasConcept C2781197716 @default.
• W4385064084 hasConcept C34626388 @default.
• W4385064084 hasConcept C38180746 @default.
• W4385064084 hasConcept C50382708 @default.
• W4385064084 hasConcept C55493867 @default.
• W4385064084 hasConcept C58471807 @default.
• W4385064084 hasConcept C71924100 @default.
• W4385064084 hasConcept C76318530 @default.
• W4385064084 hasConcept C90924648 @default.
• W4385064084 hasConceptScore W4385064084C126322002 @default.
• W4385064084 hasConceptScore W4385064084C142724271 @default.
• W4385064084 hasConceptScore W4385064084C143998085 @default.
• W4385064084 hasConceptScore W4385064084C144301174 @default.
• W4385064084 hasConceptScore W4385064084C185592680 @default.
• W4385064084 hasConceptScore W4385064084C2776914184 @default.
• W4385064084 hasConceptScore W4385064084C2777472916 @default.
• W4385064084 hasConceptScore W4385064084C2777761686 @default.
• W4385064084 hasConceptScore W4385064084C2778963024 @default.
• W4385064084 hasConceptScore W4385064084C2780140570 @default.
• W4385064084 hasConceptScore W4385064084C2781197716 @default.
• W4385064084 hasConceptScore W4385064084C34626388 @default.
• W4385064084 hasConceptScore W4385064084C38180746 @default.
• W4385064084 hasConceptScore W4385064084C50382708 @default.
• W4385064084 hasConceptScore W4385064084C55493867 @default.
• W4385064084 hasConceptScore W4385064084C58471807 @default.
• W4385064084 hasConceptScore W4385064084C71924100 @default.
• W4385064084 hasConceptScore W4385064084C76318530 @default.
• W4385064084 hasConceptScore W4385064084C90924648 @default.
• W4385064084 hasIssue "1" @default.
• W4385064084 hasLocation W43850640841 @default.

• next