Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385064327> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4385064327 abstract "Abstract Purpose To determine whether the rare NLRP3-Associated Autoinflammatory Disease ( NLRP3 -AID) is associated with retinal changes and to assess the ocular involvement. Methods A retrospective cohort study of 20 patients(40 eyes) diagnosed with rare NLRP3-AID at Peking Union Medical College Hospital, from April 2015 to August 2022. Patients underwent a comprehensive ophthalmological examination, including visual acuity, intraocular pressure examination, slit-lamp examination, fundus photography, optical coherence tomography(OCT), and fluorescence angiography (FA). Some patients also underwent optical coherence tomography angiography (OCTA). Results This study analyzed 40 eyes of 20 patients (11 [55.0%] male; median age, 25.0 years [range, 12–52 years]) and 13 patients (26 eyes, 65%) demonstrated ocular involvement. The most common ophthalmologic manifestation was conjunctivitis (22 eyes, 84.6%), followed by papilledema (14 eyes, 53.8%), retinopathy (10 eyes, 38.5%), optic atrophy (6 eyes, 23.1%), uveitis (4 eyes, 15.4%), reduced pupil light reflex (3 eyes, 11.5%) and cataracts (2 eyes, 7.7%). Ocular involvement was bilateral in 11 patients (55.0%). Five kinds of retinal lesions were seen in 5 patients (10 eyes, 25%) with NLRP3 -AID, including peripheral retinal vascular leakage, microaneurysms, macular ischemia, macular epiretinal membrane formation and drusen. Conclusions Peripheral retinal vascular leakage, macular ischemia, microaneurysms and drusen are newly identified retinal findings in patients with NLRP3 -AID, which suggests the importance of detailed retinal examination in these patients." @default.
- W4385064327 created "2023-07-23" @default.
- W4385064327 creator A5005326069 @default.
- W4385064327 creator A5012647424 @default.
- W4385064327 creator A5027647191 @default.
- W4385064327 creator A5047685668 @default.
- W4385064327 creator A5053429013 @default.
- W4385064327 creator A5055848711 @default.
- W4385064327 creator A5070032210 @default.
- W4385064327 creator A5079573376 @default.
- W4385064327 creator A5082388650 @default.
- W4385064327 creator A5083581319 @default.
- W4385064327 creator A5085024440 @default.
- W4385064327 creator A5086436968 @default.
- W4385064327 date "2023-07-21" @default.
- W4385064327 modified "2023-09-26" @default.
- W4385064327 title "New retinal findings in NLRP3-associated autoinflammatory disease" @default.
- W4385064327 cites W1524848610 @default.
- W4385064327 cites W1972724111 @default.
- W4385064327 cites W1993134828 @default.
- W4385064327 cites W1996483308 @default.
- W4385064327 cites W2009004909 @default.
- W4385064327 cites W200920675 @default.
- W4385064327 cites W2009800174 @default.
- W4385064327 cites W2106652759 @default.
- W4385064327 cites W2173787002 @default.
- W4385064327 cites W2277325960 @default.
- W4385064327 cites W2527759663 @default.
- W4385064327 cites W2547889494 @default.
- W4385064327 cites W2919321004 @default.
- W4385064327 cites W2943877762 @default.
- W4385064327 cites W2994499568 @default.
- W4385064327 cites W3021523856 @default.
- W4385064327 cites W3122351110 @default.
- W4385064327 cites W3165241217 @default.
- W4385064327 cites W3168732673 @default.
- W4385064327 cites W4234035564 @default.
- W4385064327 cites W4282036309 @default.
- W4385064327 cites W4309231179 @default.
- W4385064327 cites W4309243402 @default.
- W4385064327 doi "https://doi.org/10.1186/s13023-023-02815-1" @default.
- W4385064327 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37480029" @default.
- W4385064327 hasPublicationYear "2023" @default.
- W4385064327 type Work @default.
- W4385064327 citedByCount "0" @default.
- W4385064327 crossrefType "journal-article" @default.
- W4385064327 hasAuthorship W4385064327A5005326069 @default.
- W4385064327 hasAuthorship W4385064327A5012647424 @default.
- W4385064327 hasAuthorship W4385064327A5027647191 @default.
- W4385064327 hasAuthorship W4385064327A5047685668 @default.
- W4385064327 hasAuthorship W4385064327A5053429013 @default.
- W4385064327 hasAuthorship W4385064327A5055848711 @default.
- W4385064327 hasAuthorship W4385064327A5070032210 @default.
- W4385064327 hasAuthorship W4385064327A5079573376 @default.
- W4385064327 hasAuthorship W4385064327A5082388650 @default.
- W4385064327 hasAuthorship W4385064327A5083581319 @default.
- W4385064327 hasAuthorship W4385064327A5085024440 @default.
- W4385064327 hasAuthorship W4385064327A5086436968 @default.
- W4385064327 hasBestOaLocation W43850643271 @default.
- W4385064327 hasConcept C118487528 @default.
- W4385064327 hasConcept C2776391266 @default.
- W4385064327 hasConcept C2776474195 @default.
- W4385064327 hasConcept C2778257484 @default.
- W4385064327 hasConcept C2780248432 @default.
- W4385064327 hasConcept C2780827179 @default.
- W4385064327 hasConcept C71924100 @default.
- W4385064327 hasConceptScore W4385064327C118487528 @default.
- W4385064327 hasConceptScore W4385064327C2776391266 @default.
- W4385064327 hasConceptScore W4385064327C2776474195 @default.
- W4385064327 hasConceptScore W4385064327C2778257484 @default.
- W4385064327 hasConceptScore W4385064327C2780248432 @default.
- W4385064327 hasConceptScore W4385064327C2780827179 @default.
- W4385064327 hasConceptScore W4385064327C71924100 @default.
- W4385064327 hasIssue "1" @default.
- W4385064327 hasLocation W43850643271 @default.
- W4385064327 hasLocation W43850643272 @default.
- W4385064327 hasLocation W43850643273 @default.
- W4385064327 hasOpenAccess W4385064327 @default.
- W4385064327 hasPrimaryLocation W43850643271 @default.
- W4385064327 hasRelatedWork W2036214396 @default.
- W4385064327 hasRelatedWork W2040583314 @default.
- W4385064327 hasRelatedWork W2095345573 @default.
- W4385064327 hasRelatedWork W2265567290 @default.
- W4385064327 hasRelatedWork W2386587489 @default.
- W4385064327 hasRelatedWork W2389548857 @default.
- W4385064327 hasRelatedWork W2562951828 @default.
- W4385064327 hasRelatedWork W2754965549 @default.
- W4385064327 hasRelatedWork W3031492198 @default.
- W4385064327 hasRelatedWork W4210361733 @default.
- W4385064327 hasVolume "18" @default.
- W4385064327 isParatext "false" @default.
- W4385064327 isRetracted "false" @default.
- W4385064327 workType "article" @default.