Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385064785> ?p ?o ?g. }
- W4385064785 endingPage "e0284317" @default.
- W4385064785 startingPage "e0284317" @default.
- W4385064785 abstract "A total of 24 chromosome-specific fluorescence in situ hybridization probes for interphase nucleus analysis were developed to determine the chromosomal content of individual human invasive cytotrophoblasts derived from in v itro cultured assays. At least 75% of invasive cytotrophoblasts were hyperdiploid and the total number of chromosomes ranged from 47 to 61. The results also demonstrated that these hyperdiploid invasive cytotrophoblasts showed significant heterogeneity. The most copy number gains were observed for chromosomes 13, 14, 15, 19, 21, and 22 with average copy number greater than 2.3. A parallel study using primary invasive cytotrophoblasts also showed a similar trend of copy number changes. Conclusively, 24-chromosome analysis of human non-proliferating cytotrophoblasts (interphase nuclei) was achieved. Hyperdiploidy and chromosomal heterogeneity without endoduplication in invasive cytotrophoblasts may suggest a selective advantage for invasion and short lifespan during normal placental development." @default.
- W4385064785 created "2023-07-23" @default.
- W4385064785 creator A5000479509 @default.
- W4385064785 creator A5007403200 @default.
- W4385064785 creator A5010198496 @default.
- W4385064785 creator A5014959446 @default.
- W4385064785 creator A5018780496 @default.
- W4385064785 creator A5092515746 @default.
- W4385064785 date "2023-07-21" @default.
- W4385064785 modified "2023-10-14" @default.
- W4385064785 title "Analysis of human invasive cytotrophoblasts demonstrates mosaic aneuploidy" @default.
- W4385064785 cites W131898812 @default.
- W4385064785 cites W1488012712 @default.
- W4385064785 cites W1489743974 @default.
- W4385064785 cites W1544282464 @default.
- W4385064785 cites W1548662689 @default.
- W4385064785 cites W1981949845 @default.
- W4385064785 cites W1987912870 @default.
- W4385064785 cites W1988773194 @default.
- W4385064785 cites W1989207860 @default.
- W4385064785 cites W1990909310 @default.
- W4385064785 cites W1991849405 @default.
- W4385064785 cites W1994245033 @default.
- W4385064785 cites W2015587326 @default.
- W4385064785 cites W2023780756 @default.
- W4385064785 cites W2037707648 @default.
- W4385064785 cites W2047022270 @default.
- W4385064785 cites W2048698092 @default.
- W4385064785 cites W2053385705 @default.
- W4385064785 cites W2072177711 @default.
- W4385064785 cites W2074229592 @default.
- W4385064785 cites W2082430683 @default.
- W4385064785 cites W2093929715 @default.
- W4385064785 cites W2100963977 @default.
- W4385064785 cites W2103389977 @default.
- W4385064785 cites W2116319421 @default.
- W4385064785 cites W2119626690 @default.
- W4385064785 cites W2120468749 @default.
- W4385064785 cites W2139903829 @default.
- W4385064785 cites W2145809469 @default.
- W4385064785 cites W2155925117 @default.
- W4385064785 cites W2159058759 @default.
- W4385064785 cites W2228627356 @default.
- W4385064785 cites W2235029193 @default.
- W4385064785 cites W2346728038 @default.
- W4385064785 cites W2485046853 @default.
- W4385064785 cites W2608055428 @default.
- W4385064785 cites W2746740668 @default.
- W4385064785 cites W2785963602 @default.
- W4385064785 cites W2802753446 @default.
- W4385064785 cites W2803861957 @default.
- W4385064785 cites W2809971539 @default.
- W4385064785 cites W2942777904 @default.
- W4385064785 cites W2970004695 @default.
- W4385064785 cites W2991505993 @default.
- W4385064785 cites W4253880287 @default.
- W4385064785 doi "https://doi.org/10.1371/journal.pone.0284317" @default.
- W4385064785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37478076" @default.
- W4385064785 hasPublicationYear "2023" @default.
- W4385064785 type Work @default.
- W4385064785 citedByCount "0" @default.
- W4385064785 crossrefType "journal-article" @default.
- W4385064785 hasAuthorship W4385064785A5000479509 @default.
- W4385064785 hasAuthorship W4385064785A5007403200 @default.
- W4385064785 hasAuthorship W4385064785A5010198496 @default.
- W4385064785 hasAuthorship W4385064785A5014959446 @default.
- W4385064785 hasAuthorship W4385064785A5018780496 @default.
- W4385064785 hasAuthorship W4385064785A5092515746 @default.
- W4385064785 hasBestOaLocation W43850647851 @default.
- W4385064785 hasConcept C104317684 @default.
- W4385064785 hasConcept C153911025 @default.
- W4385064785 hasConcept C172680121 @default.
- W4385064785 hasConcept C2776953305 @default.
- W4385064785 hasConcept C2777542201 @default.
- W4385064785 hasConcept C2777605040 @default.
- W4385064785 hasConcept C2779234561 @default.
- W4385064785 hasConcept C2779672484 @default.
- W4385064785 hasConcept C30481170 @default.
- W4385064785 hasConcept C54355233 @default.
- W4385064785 hasConcept C86803240 @default.
- W4385064785 hasConceptScore W4385064785C104317684 @default.
- W4385064785 hasConceptScore W4385064785C153911025 @default.
- W4385064785 hasConceptScore W4385064785C172680121 @default.
- W4385064785 hasConceptScore W4385064785C2776953305 @default.
- W4385064785 hasConceptScore W4385064785C2777542201 @default.
- W4385064785 hasConceptScore W4385064785C2777605040 @default.
- W4385064785 hasConceptScore W4385064785C2779234561 @default.
- W4385064785 hasConceptScore W4385064785C2779672484 @default.
- W4385064785 hasConceptScore W4385064785C30481170 @default.
- W4385064785 hasConceptScore W4385064785C54355233 @default.
- W4385064785 hasConceptScore W4385064785C86803240 @default.
- W4385064785 hasFunder F4320314917 @default.
- W4385064785 hasIssue "7" @default.
- W4385064785 hasLocation W43850647851 @default.
- W4385064785 hasLocation W43850647852 @default.
- W4385064785 hasLocation W43850647853 @default.
- W4385064785 hasOpenAccess W4385064785 @default.
- W4385064785 hasPrimaryLocation W43850647851 @default.