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- W4385064790 abstract "Malignant pleural effusions (MPEs) are common. They are associated with a poor prognosis and high symptom burden. Previous studies have focused primarily on breathlessness.To evaluate whether interventions to treat MPEs impact on fatigue levels and to test the feasibility of the methodology.A prospective pilot study was conducted at a single Trust's adult pleural service over a 7 month period. It used a validated outcome measure, Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) to assess fatigue levels pre-intervention for MPE, which was repeated at 7, 14 and 30 days intervals. Data were gathered on patient demographics and potential confounding factors. The feasibility of the methodology was assessed. Recruitment targets had to be revised due to the COVID-19 pandemic.Mean age was 73 years (range 44 to 88), with a predominance of lung cancer and mesothelioma (n=16/25). Patients were willing to participate and the methodology appeared acceptable. High attrition rate was due to deteriorating participant health, rather than unacceptability of study design. For those who completed 30-day follow up (n=11/25), there was an improvement in fatigue scores. The majority of patients screened were recruited to the trial.This study met its aims in confirming the acceptability of the study protocol and suggested that intervention for MPE improved fatigue levels. However, the sample size was small and a further larger statistically powered study should be undertaken before conclusions can be drawn to influence clinical practice." @default.
- W4385064790 created "2023-07-23" @default.
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- W4385064790 date "2023-07-02" @default.
- W4385064790 modified "2023-09-25" @default.
- W4385064790 title "Do interventions for malignant pleural effusions impact on patient reported fatigue levels?" @default.
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- W4385064790 doi "https://doi.org/10.12968/ijpn.2023.29.7.334" @default.
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