FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385067508> ?p ?o ?g. }

• W4385067508 endingPage "278" @default.
• W4385067508 startingPage "275" @default.
• W4385067508 abstract "According to the latest statistical data, 22% of patients with emergency abdominal surgical pathology are admitted to medical institutions with signs of peritonitis. Despite modern methods of treatment and diagnosis, the mortality rate for this pathology remains at the same level and is approximately 18–29%, and in advanced forms can reach 75–90%. Recent studies show that in an unfavorable outcome of this pathological process, a leading role is given to a progressive increase in intraabdominal pressure (IAP). The relationship between the degree of endogenous intoxication and IAP values makes it possible to quickly assess the severity of the patient’s condition and the state of central hemodynamics without additional laboratory and instrumental studies. The aim of the study was to evaluate the indicators of systemic endogenous intoxication and intraabdominal pressure and their relationship in patients with peritonitis in the pre- and postoperative period. Material and methods . This work is based on a retrospective analysis of 74 patients operated on at the clinical bases of the Department of Hospital Surgery of the Moscow State Medical University named after A.I. Evdokimov for peritonitis from January to October 2022. The main causes of acute peritonitis were perforated ulcer of the stomach or duodenum, acute intestinal obstruction, thrombosis of mesenteric vessels, acute pancreonecrosis, complicated colon cancer. The average age of patients was 49 ± 2.5 years (34-75 years), 47 women, 27 men. The severity of peritonitis was assessed based on the degree of endotoxemia according to clinical and laboratory data. To monitor intra-abdominal hypertension, IAP was measured. IAP measurement was performed on the operating table before surgery and in the early postoperative period. At the same time, compartment syndrome of the first degree was found in 51 (68%) patients, the second degree in 14 (19%) patients, and the third-fourth degree in 9 (13%) patients. For a comprehensive assessment of the patient’s condition and the effectiveness of the measures taken, the central hemodynamics was assessed and its relationship with the indicators of intra-abdominal pressure was evaluated. Comparative analysis of central hemodynamics manometry showed that with an increase in compartment syndrome, there is a clear decrease in the performance of cardiac activity indicators, requiring urgent correction. The relationship between indicators of intra-abdominal pressure and the duration of preoperative preparation was also evaluated. Conclusions . The relationship between the degree of endogenous intoxication and the degree of intra-abdominal pressure has been proven. With an increase in IAP values, the values of endogenous intoxication increase, which subsequently leads to the development of multiple organ failure. Even with the first degree of endogenous intoxication, a decrease in myocardial contractile ability is noted, which leads to the development of cardiovascular failure depending on the severity of the pathological process. The diagnosis of increased IAP syndrome has great practical value for detecting pathology and timely comprehensive treatment in the pre- and postoperative period." @default.
• W4385067508 created "2023-07-23" @default.
• W4385067508 creator A5011148020 @default.
• W4385067508 creator A5061776683 @default.
• W4385067508 creator A5063846808 @default.
• W4385067508 creator A5074240949 @default.
• W4385067508 creator A5092516232 @default.
• W4385067508 date "2023-07-21" @default.
• W4385067508 modified "2023-09-30" @default.
• W4385067508 title "Comprehensive assessment of the relationship between indicators of systemic intoxication and intra-abdominal pressure at the patients operated for peritonitis" @default.
• W4385067508 cites W2014386792 @default.
• W4385067508 cites W2061484606 @default.
• W4385067508 cites W2087803497 @default.
• W4385067508 cites W2128236691 @default.
• W4385067508 cites W4230591365 @default.
• W4385067508 doi "https://doi.org/10.30629/0023-2149-2023-101-6-275-278" @default.
• W4385067508 hasPublicationYear "2023" @default.
• W4385067508 type Work @default.
• W4385067508 citedByCount "0" @default.
• W4385067508 crossrefType "journal-article" @default.
• W4385067508 hasAuthorship W4385067508A5011148020 @default.
• W4385067508 hasAuthorship W4385067508A5061776683 @default.
• W4385067508 hasAuthorship W4385067508A5063846808 @default.
• W4385067508 hasAuthorship W4385067508A5074240949 @default.
• W4385067508 hasAuthorship W4385067508A5092516232 @default.
• W4385067508 hasBestOaLocation W43850675081 @default.
• W4385067508 hasConcept C126322002 @default.
• W4385067508 hasConcept C141071460 @default.
• W4385067508 hasConcept C167135981 @default.
• W4385067508 hasConcept C207886595 @default.
• W4385067508 hasConcept C2780199535 @default.
• W4385067508 hasConcept C61434518 @default.
• W4385067508 hasConcept C71924100 @default.
• W4385067508 hasConcept C90924648 @default.
• W4385067508 hasConceptScore W4385067508C126322002 @default.
• W4385067508 hasConceptScore W4385067508C141071460 @default.
• W4385067508 hasConceptScore W4385067508C167135981 @default.
• W4385067508 hasConceptScore W4385067508C207886595 @default.
• W4385067508 hasConceptScore W4385067508C2780199535 @default.
• W4385067508 hasConceptScore W4385067508C61434518 @default.
• W4385067508 hasConceptScore W4385067508C71924100 @default.
• W4385067508 hasConceptScore W4385067508C90924648 @default.
• W4385067508 hasIssue "6" @default.
• W4385067508 hasLocation W43850675081 @default.
• W4385067508 hasOpenAccess W4385067508 @default.
• W4385067508 hasPrimaryLocation W43850675081 @default.
• W4385067508 hasRelatedWork W2003938723 @default.
• W4385067508 hasRelatedWork W2047967234 @default.
• W4385067508 hasRelatedWork W2078510975 @default.
• W4385067508 hasRelatedWork W2118496982 @default.
• W4385067508 hasRelatedWork W2376769477 @default.
• W4385067508 hasRelatedWork W2417961914 @default.
• W4385067508 hasRelatedWork W2439875401 @default.
• W4385067508 hasRelatedWork W4238867864 @default.
• W4385067508 hasRelatedWork W2163085110 @default.
• W4385067508 hasRelatedWork W2525756941 @default.
• W4385067508 hasVolume "101" @default.
• W4385067508 isParatext "false" @default.
• W4385067508 isRetracted "false" @default.
• W4385067508 workType "article" @default.