Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385152298> ?p ?o ?g. }
- W4385152298 endingPage "609" @default.
- W4385152298 startingPage "595" @default.
- W4385152298 abstract "Antibiotics against bacterial infections have been very successful in terms of the amelioration of diseases and the prevention of millions of deaths. However, widespread antibiotic usage has also led to an increased prevalence of antibiotic resistance, which causes debilitating multidrug-resistant infections with huge economic burdens. The use of probiotics offers a promising approach that could lower the risk of contracting bacterial infections and reduce the incidence of antibiotic resistance. There are several mechanisms that would help explain how probiotics might combat bacterial infections and antibiotic resistance. These include the production of bacteriocins which eliminate other pathogenic bacteria through competitive exclusion, production of siderophores, H2O2, and biosurfactants. Probiotics also stabilize the intestinal epithelial barrier, enhance the integrity of mucosal cells, and reduce pathogen mobility. Furthermore, probiotics modulate the immune response by producing anti-inflammatory cytokines such as interleukins, tumor necrosis factors, interferon-γ, transforming growth factors, and chemokines from antigen-presenting cells involved in the immune system. This could result in the reduction of intestinal inflammation, activation of toll-like receptors signaling pathways, and the suppression of proinflammatory cytokine expressions which were observed to lower the incidence of bacterial infections. This chapter evaluates the potential of probiotics in the reduction of the risk of infections caused by bacteria and the prevention of antibiotic resistance, elaborates on the mechanism of probiotic action against bacteria, and how probiotic use could modulate the immune response to confer protection to the host." @default.
- W4385152298 created "2023-07-23" @default.
- W4385152298 creator A5031883144 @default.
- W4385152298 creator A5035976765 @default.
- W4385152298 creator A5056576319 @default.
- W4385152298 date "2023-01-01" @default.
- W4385152298 modified "2023-10-16" @default.
- W4385152298 title "Probiotics: A solution to the prevention of antimicrobial resistance" @default.
- W4385152298 cites W1512595753 @default.
- W4385152298 cites W1926839900 @default.
- W4385152298 cites W1964418832 @default.
- W4385152298 cites W1970390134 @default.
- W4385152298 cites W1981859401 @default.
- W4385152298 cites W1982551127 @default.
- W4385152298 cites W1987838634 @default.
- W4385152298 cites W1994350585 @default.
- W4385152298 cites W1999164610 @default.
- W4385152298 cites W2004884143 @default.
- W4385152298 cites W2014689449 @default.
- W4385152298 cites W2017406716 @default.
- W4385152298 cites W2019293613 @default.
- W4385152298 cites W2022124341 @default.
- W4385152298 cites W2029945723 @default.
- W4385152298 cites W2033353018 @default.
- W4385152298 cites W2034598453 @default.
- W4385152298 cites W2043348459 @default.
- W4385152298 cites W2043560864 @default.
- W4385152298 cites W2044551431 @default.
- W4385152298 cites W2049091796 @default.
- W4385152298 cites W2065505876 @default.
- W4385152298 cites W2090797369 @default.
- W4385152298 cites W2095312487 @default.
- W4385152298 cites W2096152150 @default.
- W4385152298 cites W2100148691 @default.
- W4385152298 cites W2103267108 @default.
- W4385152298 cites W2106248075 @default.
- W4385152298 cites W2151741247 @default.
- W4385152298 cites W2158032510 @default.
- W4385152298 cites W2169921310 @default.
- W4385152298 cites W2169966827 @default.
- W4385152298 cites W2170241563 @default.
- W4385152298 cites W2223686538 @default.
- W4385152298 cites W2291264396 @default.
- W4385152298 cites W2333275146 @default.
- W4385152298 cites W2340609106 @default.
- W4385152298 cites W2528330332 @default.
- W4385152298 cites W2549679675 @default.
- W4385152298 cites W2562439197 @default.
- W4385152298 cites W2606947800 @default.
- W4385152298 cites W2737489098 @default.
- W4385152298 cites W2752001103 @default.
- W4385152298 cites W2759258829 @default.
- W4385152298 cites W2768367864 @default.
- W4385152298 cites W2793072766 @default.
- W4385152298 cites W2793636430 @default.
- W4385152298 cites W2803487426 @default.
- W4385152298 cites W2806100162 @default.
- W4385152298 cites W2808697773 @default.
- W4385152298 cites W2888529823 @default.
- W4385152298 cites W2894950133 @default.
- W4385152298 cites W2897981765 @default.
- W4385152298 cites W2901537030 @default.
- W4385152298 cites W2906114564 @default.
- W4385152298 cites W2907501709 @default.
- W4385152298 cites W2908921604 @default.
- W4385152298 cites W2914389235 @default.
- W4385152298 cites W2914734699 @default.
- W4385152298 cites W2920503665 @default.
- W4385152298 cites W2943320595 @default.
- W4385152298 cites W2969672444 @default.
- W4385152298 cites W2981502342 @default.
- W4385152298 cites W2996930110 @default.
- W4385152298 cites W2998299349 @default.
- W4385152298 cites W3005597137 @default.
- W4385152298 cites W3005762667 @default.
- W4385152298 cites W3014980518 @default.
- W4385152298 cites W3042918230 @default.
- W4385152298 cites W3044489134 @default.
- W4385152298 cites W3094541194 @default.
- W4385152298 cites W3095869439 @default.
- W4385152298 cites W3097663811 @default.
- W4385152298 cites W3105253459 @default.
- W4385152298 cites W3135026481 @default.
- W4385152298 cites W3136190838 @default.
- W4385152298 cites W3146750499 @default.
- W4385152298 cites W3183027397 @default.
- W4385152298 cites W3191361696 @default.
- W4385152298 cites W4206677002 @default.
- W4385152298 cites W4220750497 @default.
- W4385152298 cites W4230403465 @default.
- W4385152298 doi "https://doi.org/10.1016/b978-0-323-95388-7.00017-6" @default.
- W4385152298 hasPublicationYear "2023" @default.
- W4385152298 type Work @default.
- W4385152298 citedByCount "0" @default.
- W4385152298 crossrefType "book-chapter" @default.
- W4385152298 hasAuthorship W4385152298A5031883144 @default.
- W4385152298 hasAuthorship W4385152298A5035976765 @default.
- W4385152298 hasAuthorship W4385152298A5056576319 @default.