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- W4385154114 abstract "Age-related macular degeneration (AMD) is a major cause of blindness worldwide with an increasing prevalence as the population ages. The recent advances in AMD pathophysiology understanding and nanomedicine have interconnected these two subjects, and nowadays nanotechnology-based strategies are being extensively tested for overcoming AMD current treatment constraints, as the short time of anti-vascular endothelial growth factor (anti-VEGF) drugs action with frequent need for injections, the exclusive intravitreal delivery of anti-VEGF drugs, and the absence of a clinical available treatment for geographic atrophy. Nanoliposomes, nanoparticles, nanoemulsions, and nanomicelles usage have been proposed for extending drug action time, in the development of alternative methods for drug delivery, and in the search for treatments for geographic atrophy. Studies are experimental, and there is still lots to be addressed about safety and toxicity before nanotechnology-based treatments are available in the clinical setting for AMD." @default.
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- W4385154114 date "2023-01-01" @default.
- W4385154114 modified "2023-10-05" @default.
- W4385154114 title "Nanotechnology in age-related macular degeneration" @default.
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- W4385154114 doi "https://doi.org/10.1016/b978-0-443-15264-1.00001-4" @default.
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