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• W4385173895 abstract "This study aimed to show presence of Quorum Sensing (QS) signals of Gram-negative and Gram-positive biofilm producing bacteria isolated from real dairy process lines. Defining the profile and chemical composition of QS-signals is an important factor in control of microbial resistance and biofilm production. We especially focused on unusual behaviour of Gram-positive and Gram-negative isolates. Long-chain acyl-homoserine lactones (AHLs) signals (C14-HSL, C16-HSL and C18-HSL) and DFD (4,5-dihidroksi-2,3-pentanedione)-AI-2 signals of the isolates were studied by High-performance liquid chromatography (HPLC) and Liquid Chromatography with tandem mass spectrometry (LC-MSMS) methods. All Gram-positive isolates were defined as AHL-producers. All Gram-negative isolates, formerly defined as non-AHL producers by both biosensors and HPLC methods, were identified as AHL-producers. DFD signal was only detected from Gram-negative Klebsiella pneumonia, Enterobacter cloacae and Klebsiella oxytoca isolates. The results demonstrated that the QS-system is a complex system and biosensor microorganism may not be the best method for QS-signal identification. The results also provided new insights in defining the profile and chemical composition of QS-signals importance for interrupting the chemical communication completely to reduce biofilm formation and prevent resistance gain of microorganisms." @default.
• W4385173895 created "2023-07-24" @default.
• W4385173895 creator A5053280664 @default.
• W4385173895 date "2023-07-23" @default.
• W4385173895 modified "2023-10-16" @default.
• W4385173895 title "Quorum Sensing Signals Evaluation of Strong Biofilm Producer Bacteria via LC-MSMS, HPLC and Biosensors" @default.
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• W4385173895 doi "https://doi.org/10.23902/trkjnat.1276562" @default.
• W4385173895 hasPublicationYear "2023" @default.
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