FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385192306> ?p ?o ?g. }

• W4385192306 endingPage "e1004242" @default.
• W4385192306 startingPage "e1004242" @default.
• W4385192306 abstract "Micronutrient-fortified balanced energy-protein (BEP) supplements are promising interventions to prevent intrauterine growth retardation in low- and middle-income countries. On the other hand, one concern with blanket prenatal supplementation programs using energy-dense supplements is that they could lead to more maternal and/or infant overweight. However, evidence is lacking on the potential effect of BEP on maternal and offspring body composition. This study evaluates the effects of micronutrient-fortified BEP supplementation during pregnancy on body composition of mothers and their newborns in rural Burkina Faso.The MISAME-III study is an open label individually randomized controlled trial where pregnant women (n = 1,897) of gestational age <21 weeks received either a combination of micronutrient-fortified BEP and iron-folic acid (IFA) tablets (i.e., intervention) or IFA alone (i.e., control). The prenatal phase of the MISAME-III study was conducted between the first enrollment in October 2019 and the last delivery in August 2021. In a sub-study nested under the MISAME-III trial, we evaluated anthropometry and body composition in newborns who were born starting from 17 November 2020 (n: control = 368 and intervention = 352) and their mothers (n: control = 185 and intervention = 186). Primary study outcomes were newborn and maternal fat-free mass (FFMI) and fat-mass (FMI) indices. We used the deuterium dilution method to determine FFMI and FMI and %FFM and %FM of total body weight within 1 month postpartum. Our main analysis followed a modified intention-to-treat approach by analyzing all subjects with body composition data available. Univariable and multivariable linear regression models were fitted to compare the intervention and control arms, with adjusted models included baseline maternal age, height, arm fat index, hemoglobin concentration and primiparity, household size, wealth and food security indices, and newborn age (days). At study enrollment, the mean ± SD maternal age was 24.8 ± 6.13 years and body mass index (BMI) was 22.1 ± 3.02 kg/m2 with 7.05% of the mothers were underweight and 11.5% were overweight. Prenatal micronutrient-fortified BEP supplementation resulted in a significantly higher FFMI in mothers (MD (mean difference): 0.45; 95% CI (confidence interval): 0.05, 0.84; P = 0.026) and newborns (MD: 0.28; 95% CI: 0.06, 0.50; P = 0.012), whereas no statistically significant effects were found on FMI. The effect of micronutrient-fortified BEP on maternal FFMI was greater among mothers from food secure households and among those with a better nutritional status (BMI ≥21.0 kg/m2 or mid-upper arm circumference (MUAC) ≥23 cm). Key limitations of the study are the relatively high degree of missing data (approximately 18%), the lack of baseline maternal body composition values, and the lack of follow-up body composition measurements to evaluate any long-term effects.Micronutrient-fortified BEP supplementation during pregnancy can increase maternal and newborn FFMI, without significant effects on FMI.ClinicalTrials.gov with identifier NCT03533712." @default.
• W4385192306 created "2023-07-25" @default.
• W4385192306 creator A5011907266 @default.
• W4385192306 creator A5019983852 @default.
• W4385192306 creator A5026300479 @default.
• W4385192306 creator A5026837641 @default.
• W4385192306 creator A5027040611 @default.
• W4385192306 creator A5031650502 @default.
• W4385192306 creator A5032622916 @default.
• W4385192306 creator A5034222172 @default.
• W4385192306 creator A5036957264 @default.
• W4385192306 creator A5037577899 @default.
• W4385192306 creator A5038041383 @default.
• W4385192306 creator A5054177711 @default.
• W4385192306 creator A5071145981 @default.
• W4385192306 creator A5072183417 @default.
• W4385192306 date "2023-07-24" @default.
• W4385192306 modified "2023-10-16" @default.
• W4385192306 title "Effect of prenatal micronutrient-fortified balanced energy-protein supplementation on maternal and newborn body composition: A sub-study from the MISAME-III randomized controlled efficacy trial in rural Burkina Faso" @default.
• W4385192306 cites W1578457266 @default.
• W4385192306 cites W1829850482 @default.
• W4385192306 cites W1845799850 @default.
• W4385192306 cites W1866517486 @default.
• W4385192306 cites W1892263002 @default.
• W4385192306 cites W1954843863 @default.
• W4385192306 cites W1986571064 @default.
• W4385192306 cites W1994919529 @default.
• W4385192306 cites W2004583907 @default.
• W4385192306 cites W2050014967 @default.
• W4385192306 cites W2057648032 @default.
• W4385192306 cites W2063827788 @default.
• W4385192306 cites W2109945964 @default.
• W4385192306 cites W2119883020 @default.
• W4385192306 cites W2132317279 @default.
• W4385192306 cites W2132651813 @default.
• W4385192306 cites W2135897417 @default.
• W4385192306 cites W2140343676 @default.
• W4385192306 cites W2141952676 @default.
• W4385192306 cites W2143004552 @default.
• W4385192306 cites W2145326403 @default.
• W4385192306 cites W2168268121 @default.
• W4385192306 cites W2233435766 @default.
• W4385192306 cites W2264616483 @default.
• W4385192306 cites W2304553454 @default.
• W4385192306 cites W2337338861 @default.
• W4385192306 cites W2607179274 @default.
• W4385192306 cites W2744660866 @default.
• W4385192306 cites W2797453352 @default.
• W4385192306 cites W2912174383 @default.
• W4385192306 cites W2916983087 @default.
• W4385192306 cites W2942800273 @default.
• W4385192306 cites W2945316679 @default.
• W4385192306 cites W3007245808 @default.
• W4385192306 cites W3031361580 @default.
• W4385192306 cites W3045070077 @default.
• W4385192306 cites W3133188974 @default.
• W4385192306 cites W3137332080 @default.
• W4385192306 cites W3197822882 @default.
• W4385192306 cites W4200537607 @default.
• W4385192306 cites W4220756863 @default.
• W4385192306 cites W4229332631 @default.
• W4385192306 cites W4280523736 @default.
• W4385192306 cites W4283743847 @default.
• W4385192306 cites W4288758437 @default.
• W4385192306 cites W4293418843 @default.
• W4385192306 cites W4297148457 @default.
• W4385192306 cites W4302028034 @default.
• W4385192306 cites W4319294825 @default.
• W4385192306 doi "https://doi.org/10.1371/journal.pmed.1004242" @default.
• W4385192306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37486952" @default.
• W4385192306 hasPublicationYear "2023" @default.
• W4385192306 type Work @default.
• W4385192306 citedByCount "1" @default.
• W4385192306 countsByYear W43851923062023 @default.
• W4385192306 crossrefType "journal-article" @default.
• W4385192306 hasAuthorship W4385192306A5011907266 @default.
• W4385192306 hasAuthorship W4385192306A5019983852 @default.
• W4385192306 hasAuthorship W4385192306A5026300479 @default.
• W4385192306 hasAuthorship W4385192306A5026837641 @default.
• W4385192306 hasAuthorship W4385192306A5027040611 @default.
• W4385192306 hasAuthorship W4385192306A5031650502 @default.
• W4385192306 hasAuthorship W4385192306A5032622916 @default.
• W4385192306 hasAuthorship W4385192306A5034222172 @default.
• W4385192306 hasAuthorship W4385192306A5036957264 @default.
• W4385192306 hasAuthorship W4385192306A5037577899 @default.
• W4385192306 hasAuthorship W4385192306A5038041383 @default.
• W4385192306 hasAuthorship W4385192306A5054177711 @default.
• W4385192306 hasAuthorship W4385192306A5071145981 @default.
• W4385192306 hasAuthorship W4385192306A5072183417 @default.
• W4385192306 hasBestOaLocation W43851923061 @default.
• W4385192306 hasConcept C126322002 @default.
• W4385192306 hasConcept C131872663 @default.
• W4385192306 hasConcept C142724271 @default.
• W4385192306 hasConcept C14522933 @default.
• W4385192306 hasConcept C168563851 @default.
• W4385192306 hasConcept C187212893 @default.
• W4385192306 hasConcept C2775887326 @default.
• W4385192306 hasConcept C2779234561 @default.

• next