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- W4385211098 abstract "Poly(etheretherketone) (PEEK) is regarded as an attractive orthopedic material because of its good biocompatibility and mechanical properties similar to natural bone. The efficient activation methods for the surfaces of PEEK matrix materials have become a hot research topic. In this study, a method using a femtosecond laser (FSL) followed by hydroxylation was developed to achieve efficient bioactivity. It produces microstructures, amorphous carbon, and grafted −OH groups on the PEEK surface to enhance hydrophilicity and surface energy. Both experimental and simulation results show that our modification leads to a superior ability to induce apatite deposition on the PEEK surface. The results also demonstrate that efficient grafting of C–OH through FSL–hydroxylation can effectively enhance cell proliferation and osteogenic differentiation compared to other modifications, thus improving osteogenic activity. Overall, FSL hydroxylation treatment is proved to be a simple, efficient, and environmentally friendly modification method for PEEK activation. It could expand the applications of PEEK in orthopedics, as well as promote the surface modification and structural design of other polymeric biomaterials to enhance bioactivity." @default.
- W4385211098 created "2023-07-25" @default.
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- W4385211098 date "2023-07-24" @default.
- W4385211098 modified "2023-10-16" @default.
- W4385211098 title "Efficient Osteogenic Activity of PEEK Surfaces Achieved by Femtosecond Laser–Hydroxylation" @default.
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- W4385211098 doi "https://doi.org/10.1021/acsami.3c06430" @default.
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