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• W4385215542 abstract "Objectives To estimate age-specific, sex-specific, and race-specific incidence of posterior reversible encephalopathy syndrome (PRES) in the United States. Methods We conducted a retrospective cohort study using the State Inpatient Database of Florida (2016–2019), Maryland (2016–2019), and New York (2016–2018). All new cases of PRES in adults (18 years or older) were combined with Census data to compute incidence. We evaluated the generalizability of incident estimates to the entire country using the 2016–2019 National Readmissions Database (NRD). Results Across the study period, there were 3,716 incident hospitalizations for PRES in the selected states. The age-standardized and sex-standardized incidence of PRES was 2.7 (95% CI 2.5–2.8) cases/100,000/y. Incidence in female patients was >2 times that of male patients (3.7 vs 1.6 cases/100,000/y, p < 0.001). Incidence increased with age in both sexes ( p -trend <0.001). Similar demographic distribution of first hospitalization for PRES was also noted in the entire country using the NRD. Age-standardized and sex-standardized PRES incidence in Black patients (4.2/100,000/y) was significantly greater than in Non-Hispanic White (2.7/100,000/y) and Hispanic patients (1.2/100,000/y) ( p < 0.001 for pairwise comparisons). Discussion The incidence of PRES in the United States is approximately 3/100,000/y, but incidence in female patients is >2 times that of male patients. PRES incidence is higher in Black compared with non-Hispanic White and Hispanic patients." @default.
• W4385215542 created "2023-07-25" @default.
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• W4385215542 date "2023-07-24" @default.
• W4385215542 modified "2023-10-11" @default.
• W4385215542 title "Demographic Disparities in the Incidence, Clinical Characteristics, and Outcome of Posterior Reversible Encephalopathy Syndrome in the US" @default.
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• W4385215542 doi "https://doi.org/10.1212/wnl.0000000000207604" @default.
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