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- W4385233529 abstract "Abstract Objective This study aimed to determine the effect of Photobiomodulation (PBM) in the treatment of recurrent herpes labialis (RHL), one of the most common herpes simplex virus type 1 infections. Material and Methods In this single-blind randomized clinical trial, Twenty-four symptomatic patients with RHL were enrolled. The patients were randomly allocated into the case (received 1% acyclovir cream with PBM 5 times a day for 5 days and control groups who received acyclovir cream similar to the regimen of the treatment group without PBM. The size of the lesions, and pain intensity (based on a visual analogue scale) were considered as the outcome. Results Our findings suggested that, pain intensity 48 hours and 72 hours after treatment in case group were significantly p < 0.001). The lesion’s size was significantly reduced on the 7th and 10th days in the case group (p < 0.05). Patients in the treatment group were significantly more satisfied with their treatment process = group (p = 0.008). Conclusion The results of the present study showed that LLLP in addition with acyclovir cream could be more efficient in treating pain intensity, lesion size, and recovery time in patients treated with recurrent herpes labialis infection. Clinical Relevance: Low laser therapy can be used as an adjuvant therapeutic tool in combination with Acyclovir in patients with Recurrent Herpes Labialis" @default.
- W4385233529 created "2023-07-26" @default.
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- W4385233529 date "2023-07-25" @default.
- W4385233529 modified "2023-09-27" @default.
- W4385233529 title "Efficacy of adjuvant Photobiomodulation with Acyclovir in herpes simplex virus type 1 recurrence ulcers treatment, a single-blind randomized clinical trial" @default.
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- W4385233529 doi "https://doi.org/10.21203/rs.3.rs-3173096/v1" @default.
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