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- W4385245767 abstract "The specifics of breeding and selection significantly affect genetic diversity and variability within a breed. We present the data obtained from the genetic analysis of 21 thoroughbred and warmblood horse breeds. The most detailed information is described from the following breeds: Arabian, Trakehner, French Trotter, Standardbred, and Soviet Heavy Horse. The analysis of 509,617 SNP variants in 87 stallions from 21 populations made it possible to estimate the genetic diversity at the genome-wide level and distinguish the studied horse breeds from each other. In this study, we searched for heterozygous and homozygous ROH regions, evaluated inbreeding using FROH analysis, and generated a population structure using Admixture 1.3 software. Our findings indicate that the Arabian breed is an ancestor of many horse breeds. The study of the full-genome architectonics of breeds is of great practical importance for preserving the genetic characteristics of breeds and managing breeding. Studies were carried out to determine homozygous regions in individual breeds and search for candidate genes in these regions. Fifty-six candidate genes for the influence of selection pressure were identified. Our research reveals genetic diversity consistent with breeding directions and the breeds' history of origin." @default.
- W4385245767 created "2023-07-26" @default.
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- W4385245767 date "2023-07-24" @default.
- W4385245767 modified "2023-10-14" @default.
- W4385245767 title "The Genetic Diversity of Stallions of Different Breeds in Russia" @default.
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- W4385245767 doi "https://doi.org/10.3390/genes14071511" @default.
- W4385245767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37510415" @default.
- W4385245767 hasPublicationYear "2023" @default.
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