Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385257310> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W4385257310 abstract "Lipotoxicity, Mitotoxicity, and Drug Targets is a Frontiers in Endocrinology Research Topic aimed to identify potential drug targets in the molecular mechanisms behind hyperlipidemia (lipotoxicity)induced mitochondrial alterations (mitotoxicity). As lipotoxicity is related to altered metabolism and the development of different chronic diseases, such as diabetes, cardiovascular diseases and neurodegenerative disorders, the goal was to bring forth potential metabolic checkpoints in lipotoxicity-induced cellular dysfunction. This Research Topic puts together different contributions regarding lipotoxicity and mitotoxicity in a broader context of diseases, and also highlights potential therapeutic strategies.Although it is clear that metabolic health is dependent on a healthy diet and hormonal homeostasis, studies addressing link between lipidemia and hormones that regulate energy metabolism, such as thyroid hormones, are limited. In a retrospective study, Zhou et al. (hyperlink to paper) demonstrated by a cross-sectional analysis the significant correlation between serum palmitic acid (PA) and thyroid dysfunction that was more remarkable in male and obese subjects. This finding highlights the close relationship between lipotoxicity and hypothyroidism, or subclinical hypothyroidism, and pointed towards potential sex-related differences in lipid metabolism and lipotoxicity progression. Further studies are needed to verify the causal association between PA and thyroid function." @default.
- W4385257310 created "2023-07-26" @default.
- W4385257310 creator A5062484636 @default.
- W4385257310 creator A5079411257 @default.
- W4385257310 creator A5081407170 @default.
- W4385257310 date "2023-07-25" @default.
- W4385257310 modified "2023-10-18" @default.
- W4385257310 title "Editorial: Lipotoxicity, mitotoxicity, and drug targets" @default.
- W4385257310 cites W1884220033 @default.
- W4385257310 cites W1995687483 @default.
- W4385257310 cites W2014671368 @default.
- W4385257310 cites W2161526491 @default.
- W4385257310 cites W2163594278 @default.
- W4385257310 cites W2741912513 @default.
- W4385257310 cites W2946407270 @default.
- W4385257310 cites W2996735647 @default.
- W4385257310 cites W3049105695 @default.
- W4385257310 cites W3166506136 @default.
- W4385257310 cites W3176489474 @default.
- W4385257310 cites W3205998772 @default.
- W4385257310 cites W4286632703 @default.
- W4385257310 doi "https://doi.org/10.3389/fendo.2023.1245111" @default.
- W4385257310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37560301" @default.
- W4385257310 hasPublicationYear "2023" @default.
- W4385257310 type Work @default.
- W4385257310 citedByCount "0" @default.
- W4385257310 crossrefType "journal-article" @default.
- W4385257310 hasAuthorship W4385257310A5062484636 @default.
- W4385257310 hasAuthorship W4385257310A5079411257 @default.
- W4385257310 hasAuthorship W4385257310A5081407170 @default.
- W4385257310 hasBestOaLocation W43852573101 @default.
- W4385257310 hasConcept C126322002 @default.
- W4385257310 hasConcept C134018914 @default.
- W4385257310 hasConcept C151730666 @default.
- W4385257310 hasConcept C2777391703 @default.
- W4385257310 hasConcept C2778096610 @default.
- W4385257310 hasConcept C2779091943 @default.
- W4385257310 hasConcept C2779343474 @default.
- W4385257310 hasConcept C44353895 @default.
- W4385257310 hasConcept C4733338 @default.
- W4385257310 hasConcept C555293320 @default.
- W4385257310 hasConcept C71924100 @default.
- W4385257310 hasConcept C86803240 @default.
- W4385257310 hasConceptScore W4385257310C126322002 @default.
- W4385257310 hasConceptScore W4385257310C134018914 @default.
- W4385257310 hasConceptScore W4385257310C151730666 @default.
- W4385257310 hasConceptScore W4385257310C2777391703 @default.
- W4385257310 hasConceptScore W4385257310C2778096610 @default.
- W4385257310 hasConceptScore W4385257310C2779091943 @default.
- W4385257310 hasConceptScore W4385257310C2779343474 @default.
- W4385257310 hasConceptScore W4385257310C44353895 @default.
- W4385257310 hasConceptScore W4385257310C4733338 @default.
- W4385257310 hasConceptScore W4385257310C555293320 @default.
- W4385257310 hasConceptScore W4385257310C71924100 @default.
- W4385257310 hasConceptScore W4385257310C86803240 @default.
- W4385257310 hasLocation W43852573101 @default.
- W4385257310 hasLocation W43852573102 @default.
- W4385257310 hasLocation W43852573103 @default.
- W4385257310 hasOpenAccess W4385257310 @default.
- W4385257310 hasPrimaryLocation W43852573101 @default.
- W4385257310 hasRelatedWork W1969025184 @default.
- W4385257310 hasRelatedWork W1979252938 @default.
- W4385257310 hasRelatedWork W2032225465 @default.
- W4385257310 hasRelatedWork W2169206971 @default.
- W4385257310 hasRelatedWork W2378290744 @default.
- W4385257310 hasRelatedWork W2584731720 @default.
- W4385257310 hasRelatedWork W2886303208 @default.
- W4385257310 hasRelatedWork W2910989958 @default.
- W4385257310 hasRelatedWork W2969331335 @default.
- W4385257310 hasRelatedWork W3169007947 @default.
- W4385257310 hasVolume "14" @default.
- W4385257310 isParatext "false" @default.
- W4385257310 isRetracted "false" @default.
- W4385257310 workType "editorial" @default.