FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385266989> ?p ?o ?g. }

• W4385266989 abstract "Introduction and objectives: After ST-segment myocardial infarction (STEMI), the impact of different adverse events on prognosis remains unknown. We aimed to assess very long-term predictors of patient-oriented composite endpoints (POCE) and investigate whether the occurrence of target vessel failure (TVF) vs a non-TVF event as the first event could potentially influence subsequent outcomes. Methods: The EXAMINATION.EXTEND trial randomized STEMI patients to receive either an everolimus-eluting stent or a bare-metal stent. The follow-up period was 10 years. Predictors of POCE (a composite of all-cause death, any myocardial infarction, or any revascularization) were evaluated in the overall study population. The patients were stratified based on the type of first event (TVF-first vs non–TVF-first) and were compared in terms of subsequent POCE. TVF was defined as a composite of cardiac death, TV myocardial infarction, or TV revascularization. Results: Out of the 1498 enrolled patients, 529 (35.3%) experienced a POCE during the 10-year follow-up. Independent predictors of POCE were age, diabetes mellitus, previous myocardial infarction, peripheral arterial disease, and multivessel coronary disease. The first event was a TVF in 296 patients and was a non-TVF in 233 patients. No significant differences were observed between TVF-first and non–TVF-first patients in terms of subsequent POCE (21.7% vs 39.3%, time ratio 1.79; 95%CI, 0.87-3.67; P = .12) or its individual components. Conclusions: At the 10-year follow-up, approximately one-third of STEMI patients had experienced at least 1 POCE. Independent predictors of these events were age, diabetes, and more extensive atherosclerotic disease. The occurrence of a TVF or a non-TVF as the first event did not seem to influence subsequent outcomes. Trial registration number: NCT04462315. Introducción y objetivos: Se desconoce el impacto pronóstico de los diferentes tipos de eventos adversos tras el infarto agudo de miocardio con elevación del segmento ST (IAMCEST). El objetivo de este trabajo es evaluar los predictores a largo plazo del objetivo combinado orientado al paciente (POCE) y si tener un fallo del vaso diana (FVD) como primer evento puede influir en los resultados. Métodos: El ensayo EXAMINATION-EXTEND aleatorizó a pacientes con IAMCEST a tratamiento con stents liberadores de everolimus o a stents convencionales, con un seguimiento de hasta 10 años. En la población del estudio, se evaluaron los predictores de POCE (combinado de mortalidad por cualquier causa, infarto de miocardio y cualquier revascularización). Se clasificó a los pacientes según el tipo de primer evento (FVD primero o FDV no primero) y comparado en términos de POCE posterior. El FVD se definió como el compuesto de muerte cardiaca, IAMCEST del vaso diana y revascularización del vaso diana. Número de ensayo: NCT04462315. Resultados: De los 1.498 pacientes del estudio, 529 (35,3%) tuvieron POCE durante el seguimiento a los 10 años. Los predictores independientes de POCE fueron la edad, la diabetes mellitus, el infarto de miocardio previo, la enfermedad arterial periférica y la enfermedad coronaria multivaso. El primer evento fue un FVD o no FVD en 296 y 233 casos respectivamente. No hubo diferencias estadísticamente significativas entre quienes tuvieron primero un FVD y los que tuvieron un evento no FVD en cuanto a POCE (el 21,7 frente al 39,3%; razón de tiempo, 1,79; IC95%, 0,87-3,67; p = 0,12) o sus componentes individuales. Conclusiones: En el seguimiento a 10 años, alrededor de un tercio de los pacientes con IAMCEST tuvo al menos 1 evento de POCE, cuyos predictores independientes fueron la edad, la diabetes mellitus y una mayor extensión de la enfermedad ateroesclerótica. Un FVD como primer evento, en comparación con un evento no FVD, no parece tener impacto en los resultados posteriores." @default.
• W4385266989 created "2023-07-27" @default.
• W4385266989 creator A5004996801 @default.
• W4385266989 creator A5009513758 @default.
• W4385266989 creator A5011188783 @default.
• W4385266989 creator A5017228301 @default.
• W4385266989 creator A5022036458 @default.
• W4385266989 creator A5027925725 @default.
• W4385266989 creator A5029227597 @default.
• W4385266989 creator A5029987462 @default.
• W4385266989 creator A5035239568 @default.
• W4385266989 creator A5038549376 @default.
• W4385266989 creator A5042829886 @default.
• W4385266989 creator A5043877348 @default.
• W4385266989 creator A5045707517 @default.
• W4385266989 creator A5047468439 @default.
• W4385266989 creator A5063792624 @default.
• W4385266989 creator A5064097470 @default.
• W4385266989 creator A5068331230 @default.
• W4385266989 creator A5072111651 @default.
• W4385266989 creator A5073855241 @default.
• W4385266989 creator A5074704083 @default.
• W4385266989 creator A5075033637 @default.
• W4385266989 creator A5077184427 @default.
• W4385266989 creator A5079151837 @default.
• W4385266989 creator A5081887838 @default.
• W4385266989 creator A5086000459 @default.
• W4385266989 creator A5092544768 @default.
• W4385266989 creator A5092544769 @default.
• W4385266989 creator A5092544770 @default.
• W4385266989 date "2023-07-01" @default.
• W4385266989 modified "2023-10-18" @default.
• W4385266989 title "Ten-year prognostic impact of target versus non-target vessel failure after STEMI. Insight from the EXAMINATION-EXTEND trial" @default.
• W4385266989 cites W1846993152 @default.
• W4385266989 cites W1970345348 @default.
• W4385266989 cites W1996608107 @default.
• W4385266989 cites W2003774081 @default.
• W4385266989 cites W2016370355 @default.
• W4385266989 cites W2032273096 @default.
• W4385266989 cites W2058234098 @default.
• W4385266989 cites W2075203189 @default.
• W4385266989 cites W2087150869 @default.
• W4385266989 cites W2112238971 @default.
• W4385266989 cites W2114531853 @default.
• W4385266989 cites W2118980586 @default.
• W4385266989 cites W2124724401 @default.
• W4385266989 cites W2130559211 @default.
• W4385266989 cites W2131720908 @default.
• W4385266989 cites W2151468302 @default.
• W4385266989 cites W2157184686 @default.
• W4385266989 cites W2169252817 @default.
• W4385266989 cites W2264767503 @default.
• W4385266989 cites W2620950555 @default.
• W4385266989 cites W2754054868 @default.
• W4385266989 cites W2808265769 @default.
• W4385266989 cites W2885555063 @default.
• W4385266989 cites W2980608465 @default.
• W4385266989 cites W3135605738 @default.
• W4385266989 cites W3138841906 @default.
• W4385266989 cites W3197001430 @default.
• W4385266989 cites W39529948 @default.
• W4385266989 cites W4210841834 @default.
• W4385266989 cites W4210952766 @default.
• W4385266989 doi "https://doi.org/10.1016/j.rec.2023.07.001" @default.
• W4385266989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37506972" @default.
• W4385266989 hasPublicationYear "2023" @default.
• W4385266989 type Work @default.
• W4385266989 citedByCount "0" @default.
• W4385266989 crossrefType "journal-article" @default.
• W4385266989 hasAuthorship W4385266989A5004996801 @default.
• W4385266989 hasAuthorship W4385266989A5009513758 @default.
• W4385266989 hasAuthorship W4385266989A5011188783 @default.
• W4385266989 hasAuthorship W4385266989A5017228301 @default.
• W4385266989 hasAuthorship W4385266989A5022036458 @default.
• W4385266989 hasAuthorship W4385266989A5027925725 @default.
• W4385266989 hasAuthorship W4385266989A5029227597 @default.
• W4385266989 hasAuthorship W4385266989A5029987462 @default.
• W4385266989 hasAuthorship W4385266989A5035239568 @default.
• W4385266989 hasAuthorship W4385266989A5038549376 @default.
• W4385266989 hasAuthorship W4385266989A5042829886 @default.
• W4385266989 hasAuthorship W4385266989A5043877348 @default.
• W4385266989 hasAuthorship W4385266989A5045707517 @default.
• W4385266989 hasAuthorship W4385266989A5047468439 @default.
• W4385266989 hasAuthorship W4385266989A5063792624 @default.
• W4385266989 hasAuthorship W4385266989A5064097470 @default.
• W4385266989 hasAuthorship W4385266989A5068331230 @default.
• W4385266989 hasAuthorship W4385266989A5072111651 @default.
• W4385266989 hasAuthorship W4385266989A5073855241 @default.
• W4385266989 hasAuthorship W4385266989A5074704083 @default.
• W4385266989 hasAuthorship W4385266989A5075033637 @default.
• W4385266989 hasAuthorship W4385266989A5077184427 @default.
• W4385266989 hasAuthorship W4385266989A5079151837 @default.
• W4385266989 hasAuthorship W4385266989A5081887838 @default.
• W4385266989 hasAuthorship W4385266989A5086000459 @default.
• W4385266989 hasAuthorship W4385266989A5092544768 @default.
• W4385266989 hasAuthorship W4385266989A5092544769 @default.
• W4385266989 hasAuthorship W4385266989A5092544770 @default.
• W4385266989 hasConcept C126322002 @default.
• W4385266989 hasConcept C164705383 @default.
• W4385266989 hasConcept C197934379 @default.

• next